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Scientists find genetic marker that indicates a person's risk for tachycardia-induced cardiomyopathy

Scientists in Japan have found a potential marker to identify which people with abnormally fast heartbeats are at high risk of developing heart failure.

9 Aug 2018

Study identifies key role of TLK1 and TLK2 enzymes in DNA replication

During cell growth, cells copy their DNA through a process called DNA replication. For this process to be accurate, the genetic and epigenetic information must be copied flawlessly.

9 Aug 2018

ETH scientists discover new cancer-specific molecular changes in tumor tissues

A research team led by Gunnar Raetsch, Professor of Biomedical Informatics at ETH Zurich, has evaluated the largest set of genetic data in cancer medicine: The Cancer Genome Atlas in the United States.

9 Aug 2018

Study finds false negatives in common tests used to determine ROS1 status in lung cancer

Drugs like crizotinib are used to treat patients with ROS1-positive lung cancer. But which patients are ROS1-positive? A University of Colorado Cancer Center study published in the Journal of Thoracic Oncology shows that common laboratory tests used to determine ROS1 status all have inherent limitations that can lead to false-negative results.

9 Aug 2018

RNA and DNA sequencing platform matches broader swath of drugs to late-stage cancer patients

A comprehensive RNA and DNA sequencing platform benefits late-stage and drug-resistant multiple myeloma patients by determining which drugs would work best for them, according to results from a clinical trial published in JCO Precision Oncology in August.

9 Aug 2018

New AI algorithm helps predict medication response in patients with complex mood disorder

Mood disorders like major depressive disorder and bipolar disorder are often complex and hard to diagnose, especially among youth when the illness is just evolving.

9 Aug 2018

Cancer cells release biological 'drones' to assist in the fight against immune system

Cancer cells are more than a lump of cells growing out of control; they participate in active combat with the immune system for their own survival. Being able to evade the immune system is a hallmark of cancer.

9 Aug 2018

New method evaluates effectiveness of interventions in mitigating spread of HIV

Using genetic sequencing to understand the evolutionary relationships among pathogens, an international team of researchers - including several from the Center for Drug Use and HIV/HCV Research at New York University - has developed a new method to determine how effective interventions are against the spread of infectious diseases like HIV.

9 Aug 2018

New drug delivery system delivers anticancer drugs that reduce tumor size

Cancer tissue cells are divided into two major groups: cancer cells and cancer stem cells. CSCs are related to cancer progression and dissemination, so it's necessary to eradicate CSCs in order to cure cancer.

9 Aug 2018

Scientists identify drug that could reverse pulmonary arterial hypertension

Scientists at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago took a major step toward developing a new treatment for pulmonary arterial hypertension, a severe lung disease with a five-year survival rate of 50 percent.

9 Aug 2018

FDA approves potassium chloride oral solution as first generic drug to receive CGT designation

The U.S. Food and Drug Administration today approved several strengths of potassium chloride oral solution as the first generic drugs to receive a Competitive Generic Therapy designation.

9 Aug 2018

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

The U.S. Food and Drug Administration today approved Poteligeo (mogamulizumab-kpkc) injection for intravenous use for the treatment of adult patients with relapsed or refractory mycosis fungoides or Sézary syndrome after at least one prior systemic therapy.

8 Aug 2018

New sensor allows scientists to measure cancer cell's response to chemotherapy drug

MIT chemical engineers have developed a new sensor that lets them see inside cancer cells and determine whether the cells are responding to a particular type of chemotherapy drug.

8 Aug 2018

Taking cholesterol-busting pills can effectively treat brutal PAP

Researchers report in Nature Communications they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary Alveolar Proteinosis, and they show taking cholesterol-busting pills called statins can effectively treat the disease.

7 Aug 2018

Extended-release naltrexone appears to help HIV-positive patients reduce heavy drinking

Extended-release naltrexone -- an injection that decreases heavy drinking in the general population when taken in conjunction with counseling -- appears to help HIV-positive individuals reduce their number of heavy drinking days too, say Yale researchers.

7 Aug 2018

New CAR T-cell immunotherapy trial targets solid tumors

Seattle Children's has opened a chimeric antigen receptor (CAR) T-cell immunotherapy trial for children and young adults with relapsed or refractory non-central nervous system EGFR-expressing solid tumors. In the phase 1 trial, STRIvE-01, cancer-fighting CAR T cells will target the EGFR protein expressed in many childhood sarcoma, kidney and neuroblastoma tumors.

7 Aug 2018

Therapy News and Research

Scientists find genetic marker that indicates a person's risk for tachycardia-induced cardiomyopathy

Study identifies key role of TLK1 and TLK2 enzymes in DNA replication

ETH scientists discover new cancer-specific molecular changes in tumor tissues

Study finds false negatives in common tests used to determine ROS1 status in lung cancer

RNA and DNA sequencing platform matches broader swath of drugs to late-stage cancer patients

New AI algorithm helps predict medication response in patients with complex mood disorder

Cancer cells release biological 'drones' to assist in the fight against immune system

New method evaluates effectiveness of interventions in mitigating spread of HIV

New drug delivery system delivers anticancer drugs that reduce tumor size

Scientists identify drug that could reverse pulmonary arterial hypertension

FDA approves potassium chloride oral solution as first generic drug to receive CGT designation

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

New sensor allows scientists to measure cancer cell's response to chemotherapy drug

Taking cholesterol-busting pills can effectively treat brutal PAP

Extended-release naltrexone appears to help HIV-positive patients reduce heavy drinking

New CAR T-cell immunotherapy trial targets solid tumors

Scientists develop a way to deliver curcumin as an anti-cancer agent

New test method offers more reliable diagnosis of diabetes insipidus

Study: Potential new class of drugs may lower heart disease risk by targeting gut microbes

Researchers identify role of infection-fighting cells in inflamed and damaged tissue

Industry Focus eBook - Cell biology (5th edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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