Cytology News and Research

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Cytology is the study of cells using a microscope.

Two interconnected signaling pathways drive papillary thyroid carcinoma progression

A new research perspective was published in Volume 13 of Oncoscience on June 3, 2026, titled "The dual axis of tumorigenesis: MAPK and PI3K/AKT pathways in papillary thyroid carcinoma."

24 Jul 2026

New microfluidic device improves tumor cell enrichment from pleural effusions

Pleural effusion cytology is already used in cancer diagnosis, especially in metastatic settings, but its sensitivity can be limited.

20 Apr 2026

Molecular test shows high sensitivity in detecting bile duct cancer

When patients develop a narrowing or blockage in the bile ducts – the tubes connecting the liver, gallbladder and intestines – physicians must determine whether the cause is cancer or a benign condition.

27 Mar 2026

One in five US women prefer at-home HPV screening

National data shows women who experience healthcare discrimination favor at-home HPV testing, raising questions about trust and access in screening guidelines.

11 Feb 2026

Menstrual blood HPV testing accurately detects cervical precancer

A study reveals menstrual blood can effectively screen for HPV, matching clinician-collected samples in accuracy, enhancing cervical cancer detection globally.

9 Feb 2026

Self-collected HPV tests match clinical screening

New data shows universal access to self-collected HPV testing boosts cervical cancer screening uptake, especially among underserved populations in Australia.

4 Feb 2026

New federal guidelines shift cervical cancer screening to HPV testing

New cervical cancer screening guidelines emphasize self-collection and hrHPV testing, aiming to increase screening rates and improve women's health outcomes.

8 Jan 2026

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Learn how digital connectivity and the PathoVerse are improving pathology workflows and accelerating access to expert diagnostics.

From PathPresenter 12 Dec 2025

Urine cfDNA patterns emerge as a promising tool for diagnosing bladder cancer

Researchers have discovered that analyzing specific patterns of cell-free DNA (cfDNA) fragmentation in a simple urine sample can effectively diagnose and stage bladder cancer, offering a much-needed alternative to invasive procedures like cystoscopies.

4 Dec 2025

Simple, affordable HPV test delivers results in less than an hour

A team of researchers led by Rice University, in collaboration with colleagues in Mozambique and The University of Texas MD Anderson Cancer Center, has developed a simple, affordable human papillomavirus (HPV) test that delivers results in less than an hour with no specialized laboratory required.

29 Sep 2025

Blocking iron-regulating enzyme triggers cancer cell death in multiple myeloma

Researchers at Duke University have shown that blocking an enzyme involved in iron regulation not only kills multiple myeloma cancer cells, but also increases the effectiveness of current therapies against the disease.

24 Sep 2025

Multi-analyte test accurately identifies brain cancers using cerebrospinal fluid

A novel, multi-analyte test developed by researchers at the Johns Hopkins Kimmel Cancer Center, its Ludwig Center and the Johns Hopkins Department of Neurosurgery can accurately identify brain cancers using small samples of cerebrospinal fluid (CSF), offering a promising new tool to guide clinical decision-making.

27 Aug 2025

Advancing diagnostic accuracy in soft tissue cytopathology through WHO guidelines

Soft tissue cytopathology plays a vital role in the diagnosis and management of soft tissue neoplasms, necessitating a standardized classification system to improve diagnostic accuracy and guide clinical decision-making.

18 Jul 2025

EAGLE model predicts key lung cancer mutations from routine biopsy

With EAGLE, lung cancer biopsy analysis is expedited, accurately predicting EGFR mutations and streamlining the diagnostic process for better patient outcomes.

14 Jul 2025

AI and deep learning transform diagnosis of oral potentially malignant disorders

Oral cancer remains a serious global health concern due to its high morbidity and mortality rates, primarily caused by late-stage diagnosis.

26 Feb 2025

Early detection of tumor spread improves treatment outcomes

A group led by the Department of Neurosurgery, Brain Research Institute, Niigata University succeeded in the diagnosis of leptomeningeal disease in diffuse midline gliomas by detecting H3K27M-mutant droplets from circulating tumor DNA of cerebrospinal fluid taken from these patients.

27 Jan 2025