Flow Cytometry News and Research

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Flow cytometry is a technique for counting and examining microscopic particles suspended in a stream of fluid. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus.

Celastrol reduces cholestatic liver injury by inhibiting specific protein

Cholestasis occurs when bile formation, secretion, or flow is impaired, causing toxic bile acids to accumulate and trigger inflammation and liver-cell damage.

17 Sep 2026

Immunotherapy combined with BCG vaccine drastically lowers tuberculosis relapse risk

Tuberculosis (TB) remains one of the world's leading causes of death, and preventing post-treatment relapse continues to be a major worldwide health challenge.

17 Sep 2026

Study shows mRNA vaccines trigger more diverse flu antibody responses

Influenza remains a major global health challenge as continual antigenic drift can limit the breadth and durability of vaccine-induced antibody responses, requiring frequent vaccine updates.

11 Sep 2026

Gut infection leaves long-lasting immune ‘memories’ at the brain’s borders in mice

In mice, intestinal infections reshaped dural CD4+ T-cell populations and seeded the brain’s outer meningeal border with antigen-specific memory cells that persisted for months and mounted rapid recall responses to bloodborne antigens. Oral priming was associated with reduced Salmonella spread to the brain and modest cross-protection in an engineered shared-antigen Candida model, although the researchers could not definitively prove that dural CD4+ T cells alone caused the protection.

9 Sep 2026

Retinal immune cell gateway may unlock targeted uveitis treatments

As part of an effort to understand the molecules and mechanisms that regulate transendothelial migration in different vascular beds of the body, researchers focused on the blood vessels of the retina, part of the blood-brain barrier.

8 Sep 2026

Scientists traced a hidden immune route that may worsen tau-linked brain damage

In a mouse model of tauopathy, conventional type 1 dendritic cells (cDC1s) cross-presented brain-derived antigens in deep cervical lymph nodes, priming CD8+ T cells that accumulated in the brain and promoted neurodegeneration. Disrupting cDC1s or their cross-presentation activity reduced CD8+ T-cell infiltration and protected against neuronal loss, while human primary tauopathy samples also showed increased brain CD8+ T cells, although cDC1 involvement in humans remains unconfirmed.

6 Sep 2026

New drug class shows major promise for shrinking nerve tumors

A scientist at Cincinnati Children's who has hunted for decades for ways to shrink the painful and disfiguring nerve tumors caused by neurofibromatosis type 1 (NF1) has made a new breakthrough in the quest.

2 Sep 2026

Advanced tools and new leadership drive Single Cell Genomics Center into the future

Bigelow Laboratory for Ocean Sciences is excited to announce the appointment of new leadership - as well as new tools, analytical services, and a bold vision for the future - for the Single Cell Genomics Center.

2 Sep 2026

Could the type of fiber children eat matter for their developing gut microbiome?

A recent study found that different dietary fibers can shape the composition and activity of the gut microbiome during early childhood, with xyloglucan, arabinoxylan, and pectin increasing short-chain fatty acid production in laboratory fermentation experiments. Some fibers also supported gut barrier measures and altered inflammatory responses, while observational data linked higher pectin intake with greater microbial diversity in young children.

31 Aug 2026

Cannabis compounds may weaken glioblastoma response to chemotherapy and radiation

Several cannabinoids reduced chemotherapy- and radiation-induced apoptosis in glioblastoma cell models, with effects linked to reduced apoptotic priming, increased pro-survival signaling, and G1 cell-cycle arrest. The findings raise concern that cannabinoid exposure could interfere with some cancer treatments, although the results are limited to laboratory models and require in vivo and clinical validation.

12 Aug 2026

Blood filtration method helps clear circulating lipids and toxic microplastics

The machine is not new. Some version of it has run in hospital treatment rooms for about four decades, drawing blood from one arm, separating out the plasma, passing it across a filter or an adsorber, and returning it to the other arm.

4 Aug 2026

Cigarette smoke extract primes airway cells for greater nanoplastic damage

Researchers found that cigarette smoke extract weakened epithelial barriers and increased the proportion of human airway cells that were polystyrene nanoparticle-positive. Sequential treatment caused greater metabolic disruption and increased mucus-producing cells, suggesting heightened epithelial vulnerability, although the findings are limited to in vitro models.

30 Jul 2026

Thymulin curbs age-related inflammation and slows breast tumors in mice

Thymulin reduced age-associated inflammatory myeloid cells and slowed breast-tumor growth in aged mice by suppressing NF-κB signaling. The peptide also restored anti-PD-L1 responsiveness in aged mouse models, while human cell and tumor data supported an age-linked inflammatory myeloid profile.

23 Jul 2026

Thymus hormone identified as key player in reversing age-related inflammation

Chronic, low-grade inflammation in the body-a phenomenon known as "inflammaging" because it increases with age-has been linked to many of today's leading causes of illness and death, including cancer, heart disease, metabolic conditions and neurodegenerative diseases.

21 Jul 2026

Targeted nanoparticles destroy tumor cells by triggering cuproptosis

A promising cancer treatment strategy called cuproptosis, which uses copper-dependent cell death to eliminate tumor cells, faces a major challenge: many approaches require adding external copper, potentially increasing toxicity beyond the tumor.

15 Jul 2026

Cold-exposed mothers pass metabolic protection to male rat offspring through milk

Maternal cold exposure during early pregnancy improved glucose control and reduced liver fat in male rat offspring, with benefits persisting into late adulthood. The findings implicate a breast milk LCA, gut microbiota, and Th17 immune pathway, while human cohort data showed an observational link between winter conception and lower MASLD risk.

12 Jul 2026

Unusual CD34+ dysplastic giant platelets complicate myelodysplastic syndrome diagnosis

Myelodysplastic syndromes (MDS) are a group of hematopoietic disorders characterized by ineffective hematopoiesis, with manifestations of cytopenias in one, two, or three lineages.

28 Jun 2026

Study reveals early immune clues to predict active tuberculosis risk

An early view of the immune response to bacteria in the lungs provides clues as to why some people keep TB in check, while others develop disease, suggesting new ways to intervene earlier and stop TB.

24 Jun 2026

New project aims to systematically map billion cellular interactions

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23 Jun 2026

Collagen exists as liquid droplets inside living cells, study reveals

Collagen, the protein that builds skin, bones, tendons and organs, exists inside cells as a liquid-like droplet rather than the long, rigid rod seen in textbooks over the last half century, according to a new study from the Centre for Genomic Regulation (CRG) in Barcelona.

11 Jun 2026