Cell Biology

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Scientific research articles show that imipridones target mitochondrial function in cancer cells

Oncoceutics, Inc. announced the publication of two scientific research articles demonstrating that members of the imipridone family ONC201 and ONC212 directly activate a mitochondrial protease called caseinolytic protease P.

7 May 2019

Unexpected role of junk RNA in cancer opens new way for treatment of the disease

In an article just published by Trends in Cancer online, Dr. Alan Herbert, founder at InsideOutBio, highlights how the way cancer cells solve the problem of junk RNA makes them vulnerable to a new type of cancer therapy.

7 May 2019

Research into cancer signaling network reveals new roadmap to tumor control

In this advanced age of molecular sleuthing, a research team led by Georgetown Lombardi Comprehensive Cancer Center have findings that suggest tumors will eventually become resistant to drug inhibitors of a common cancer pathway (dubbed YAP/TAZ), now in preclinical development.

7 May 2019

Form drives function in cancer proliferation, UTSW study finds

A new study finds that the protein responsible for the crawling movements of cells also drives the ability of cancer cells to grow when under stress.

6 May 2019

Creating biologically functional tissue using 3D printing techniques

The future of medicine is biological - and scientists hope we will soon be using 3D-printed biologically functional tissue to replace irreparably damaged tissue in the body.

6 May 2019

Messenger cells hold key to better bone healing

How do bones heal, and how could they heal better? The answer to these questions may lie in a newly discovered population of "messenger" cells, according to a recent USC Stem Cell study published in the journal eLife.

6 May 2019

MIT researchers develop novel method for analyzing massive cell datasets

Data-sampling method makes "sketches" of unwieldy biological datasets while still capturing the full diversity of cell types.

3 May 2019

Study finding promises new perspectives for treatment of Type 2 endometrial cancer

Brazilian scientists identify the predominant presence of a truncated variant of the p53 protein in amyloid aggregates in endometrial cancer cells. Such structures are related to the progression of this tumor.

3 May 2019

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

The discovery of the first small-molecule inhibitors of the Streptococcus pyogenes Cas9 (SpCas9) protein could enable more precise control over CRISPR-Cas9-based genome editing, researchers report May 2 in the journal Cell.

3 May 2019

Pathogenic bacteria find safe harbor deep in the gastric glands to maintain colonization

Scientists have long tried to understand how pathogenic bacteria like Helicobacter pylori, a risk factor for stomach ulcers and cancer, survive in the harsh environment of the stomach.

3 May 2019

Scientists describe how cells 'decide' between pluripotency and differentiation

Induced pluripotent stem cells can turn into any type of cell in the body or remain in their original form. In the current edition of Molecular Cell, scientists from the Helmholtz Zentrum München describe how cells “decide” which of these two directions to take.

3 May 2019

Novel chemical probe enables live imaging of brain immune cells

Researchers in South Korea and Singapore have, for the first time, developed a chemical probe that enables live-imaging of a type of immune cells in the brain, known as microglia, in a live animal brain.

3 May 2019

Potential stem cell therapies moving from lab bench to clinical application

Stem cell research is leading to potential new therapies to treat disease, with several applications in clinical trials or expected to enter trials in the coming months.

3 May 2019

Scientists unravel mechanism of action of antitumor drug used to treat glioblastoma

Glioblastoma is an incurable type of brain tumor that is frequently associated with mutations in the epidermal growth factor receptor.

3 May 2019

Researchers use 3D printer to make paper organs

Long before scientists test new medicines in animals or people, they study the effects of the substances on cells growing in Petri dishes.

1 May 2019

Army research may help improve cancer treatments and treat combat wounds

Army research is the first to develop computational models using a microbiology procedure that may be used to improve novel cancer treatments and treat combat wounds.

1 May 2019

Researchers gain new insight into Alzheimer's using organoids that resemble mini brains

In the majority of cases, dementia can be traced back to Alzheimer's disease. Its causes are not really understood yet. What is known is that plaques form from misfolded proteins and that there is an increase in neuronal cell death levels in the brain. However, the plaques don't necessarily go hand in hand with any symptoms.

30 Apr 2019

Scientists develop small fluorophores for tracking metabolites in living cells

Living cells can react to disturbances with a changed metabolism, but direct observation of trafficking metabolites in live cells is difficult.

30 Apr 2019

Researchers use structural biology techniques to understand how lipids bind proteins

Normal cells have a complex system of checks and balances that regulate cell division.

30 Apr 2019

How proteins in outer membrane of bacteria stick to and populate in human body

The discovery, published today in Nature Communications by researchers from La Trobe University and the University of Queensland, provides details on how proteins in the outer membrane of bacteria - the bacteria's 'superglue' - are able to stick to and populate parts of the human body.

30 Apr 2019

Cell Biology

Scientific research articles show that imipridones target mitochondrial function in cancer cells

Unexpected role of junk RNA in cancer opens new way for treatment of the disease

Research into cancer signaling network reveals new roadmap to tumor control

Form drives function in cancer proliferation, UTSW study finds

Creating biologically functional tissue using 3D printing techniques

Messenger cells hold key to better bone healing

MIT researchers develop novel method for analyzing massive cell datasets

Study finding promises new perspectives for treatment of Type 2 endometrial cancer

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

Pathogenic bacteria find safe harbor deep in the gastric glands to maintain colonization

Scientists describe how cells 'decide' between pluripotency and differentiation

Novel chemical probe enables live imaging of brain immune cells

Potential stem cell therapies moving from lab bench to clinical application

Scientists unravel mechanism of action of antitumor drug used to treat glioblastoma

Researchers use 3D printer to make paper organs

Army research may help improve cancer treatments and treat combat wounds

Researchers gain new insight into Alzheimer's using organoids that resemble mini brains

Scientists develop small fluorophores for tracking metabolites in living cells

Researchers use structural biology techniques to understand how lipids bind proteins

How proteins in outer membrane of bacteria stick to and populate in human body

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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