Cell Biology

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Mast cells found to capture and employ neutrophils during allergic reactions

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system.

2 Aug 2024

Study reveals how coinfecting phages impede each other’s entry into bacterial cells

The process by which phages - viruses that infect and replicate within bacteria - enter cells has been studied for over 50 years.

2 Aug 2024

Single-cell RNA sequencing sheds light on stroke-induced brain damage

Strokes lead to irreversible damage to the brain and are one of the most common causes of dependency or death.

1 Aug 2024

Novel anti-tuberculosis compound targets bacterial membrane protein

Researchers from Heinrich Heine University Düsseldorf (HHU) and the University of Duisburg-Essen (UDE) have together succeeded in identifying and synthesizing a group of molecules that can act against the cause of tuberculosis in a new way. In the scientific journal Cell Chemical Biology, they describe that the so-called callyaerins act against the infectious disease by employing a fundamentally different mechanism compared to antibiotic agents used to date.

1 Aug 2024

Microbes play key role in carcinogenesis

At any given time, over 10 trillion microbes call our guts their home. From breaking down nutrients in our food to strengthening our immunity against pathogens, these microbes play an essential role in how we interact with the world. This includes – as shown in a new study by EMBL researchers and collaborators at the University of Split, Croatia – the way the body responds to carcinogens and develops cancer.

1 Aug 2024

Salk Institute receives CIRM funding for stem cell research on aging and neurodegeneration

The Salk Institute was awarded $3.6 million by the California Institute for Regenerative Medicine (CIRM), one of the world's largest institutions dedicated to regenerative medicine.

31 Jul 2024

MD Anderson and collaborators initiate space project to explore T cell behavior in microgravity

The University of Texas MD Anderson Cancer Center and collaborators are initiating a research project that will send T cells to the International Space Station (ISS) to study the effects of prolonged microgravity on cell differentiation, activation, memory and exhaustion.

31 Jul 2024

Innovative tissue slicing method for improved clinical outcomes

In a pioneering development for the biomedical field, a research team led by Yuanjin Zhao from Nanjing Drum Tower Hospital, China, has published a research article in Engineering. The article, titled "Controllable Histotomy Based on Hierarchical Magnetic Microneedle Array Robots," introduces a novel technique for tissue slicing and cultivation that could revolutionize the way primary tissues are handled in clinical settings.

30 Jul 2024

ACE technology enhances single-cell protein detection with advanced signal amplification

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals.

30 Jul 2024

Study unveils dual roles of TNF-α receptors in tissue regeneration and cell death

A study published in The EMBO Journal opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work.

29 Jul 2024

Scientists explore early life factors contributing to SMA

Spinal muscular atrophy (SMA) is a severe neurological disease for which there is presently no cure, although current therapies can alleviate symptoms. In the search for better treatment options, scientists at DZNE and the Dresden University of Technology are now drawing attention to previously unnoticed abnormalities in embryonic development. They base their argument on studies of so-called organoids: Laboratory-grown tissue cultures that can reconstruct disease processes. Their findings are published in the journal Cell Reports Medicine.

27 Jul 2024

Breakthrough therapy heals spinal cord injuries

In November 2021, Northwestern University researchers introduced an injectable new therapy, which harnessed fast-moving "dancing molecules," to repair tissues and reverse paralysis after severe spinal cord injuries.

27 Jul 2024

Unraveling the microbial dynamics of spontaneous fermentation

Shibazuke is a traditional Japanese eggplant pickle produced by the process of fermentation using lactic acid bacteria (LAB). LAB which is commonly present in vegetables causes the spontaneous fermentation of vegetables, resulting in the distinctive acidic flavor of pickles. While LAB is beneficial, other species of bacteria and microbes that may be present in the food source can affect the food quality and safety. Advancements in the areas of food technology and nutrition have allowed the large-scale fermentation of pickles via industrial fermenters, where conditions that affect fermentation like temperature, pH-acid levels, and salt content are closely monitored.

27 Jul 2024

INTEGRA Biosciences and Parse Biosciences offer affordable, automated single cell RNA sequencing

INTEGRA Biosciences and Parse Biosciences have partnered to automate single cell RNA sequencing (scRNA-seq) on the ASSIST PLUS pipetting robot.

From INTEGRA Biosciences 26 Jul 2024

Electrical currents could supercharge cancer-killing immune cells, study finds

Scientists have discovered that electrical currents may make Natural Killer (NK) cells – our very own cancer-killing immune cells – even better killers, which could have significant implications for treating some cancers.

25 Jul 2024

Stanford's muscle chips reveal microgravity's impact on muscle regeneration

A gentle rumble ran under Ngan Huang's feet as a rocket carrying her research - live, human muscle cells grown on scaffolds fixed on tiny chips - lifted off, climbed, and disappeared into the sky to the International Space Station National Laboratory.

25 Jul 2024

Study highlights infection as major post-CAR-T therapy challenge

In patients with diffuse large B-cell non-Hodgkin lymphoma (DLBCL), the two hallmark post-chimeric antigen receptor (CAR)-T therapy toxicities are extremely rare after two weeks, supporting a shorter, more flexible toxicity monitoring period, according to a study published in Blood Advances.

25 Jul 2024

Cell Biology

Mast cells found to capture and employ neutrophils during allergic reactions

Study reveals how coinfecting phages impede each other’s entry into bacterial cells

Single-cell RNA sequencing sheds light on stroke-induced brain damage

Novel anti-tuberculosis compound targets bacterial membrane protein

Microbes play key role in carcinogenesis

Salk Institute receives CIRM funding for stem cell research on aging and neurodegeneration

MD Anderson and collaborators initiate space project to explore T cell behavior in microgravity

Innovative tissue slicing method for improved clinical outcomes

ACE technology enhances single-cell protein detection with advanced signal amplification

Study unveils dual roles of TNF-α receptors in tissue regeneration and cell death

Scientists explore early life factors contributing to SMA

Breakthrough therapy heals spinal cord injuries

Unraveling the microbial dynamics of spontaneous fermentation

INTEGRA Biosciences and Parse Biosciences offer affordable, automated single cell RNA sequencing

Electrical currents could supercharge cancer-killing immune cells, study finds

Stanford's muscle chips reveal microgravity's impact on muscle regeneration

Study highlights infection as major post-CAR-T therapy challenge

Unprecedented brain cell mapping sheds light on Alzheimer's

New insights into p16 protein could lead to advances in cancer diagnosis and treatment

Cryo-electron microscopy reveals how membrane microdomains respond to mechanical stress

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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