Cell Biology

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McGill discovery offers hope for targeted stem cell treatments

A new technique developed by McGill researchers for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential.

13 Aug 2024

Cell adhesion and starvation found to be key drivers of pattern formation in keratinocytes

Cell-cell adhesion-induced patterning in keratinocytes can be explained by just starvation and strong adhesion, Hokkaido University researchers find.

12 Aug 2024

New research identifies key protein complex in cellular quality control

Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease.

12 Aug 2024

Cell nuclei found to control tissue architecture in eye and brain development

In work conducted both at UC Santa Barbara and the Physics of Life Excellence Cluster of TU Dresden, biophysicist Otger Campàs and his research group have found that cell nuclei control the architecture and mechanics of eye and brain tissues during embryonic development.

12 Aug 2024

Study reveals how light-activated macrophages increase their appetite for cancer cells

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer.

12 Aug 2024

New histone tag discovery offers hope for myelin repair in neurodegenerative diseases

In a groundbreaking study, researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have identified a distinct histone tag in adult oligodendrocyte progenitor cells (OPCs) that may pave the way for innovative therapies targeting myelin repair, a critical target for several neurodegenerative and psychiatric disorders, including multiple sclerosis, Alzheimer's disease, and schizophrenia.

12 Aug 2024

Mechanisms of tissue shape transformation revealed through fruit fly wing development

A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development.

9 Aug 2024

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

A discovery by a three-member Albert Einstein College of Medicine research team may boost the effectiveness of stem-cell transplants, commonly used for patients with cancer, blood disorders, or autoimmune diseases caused by defective stem cells, which produce all the body's different blood cells.

8 Aug 2024

ProDOL revolutionizes protein quantification in living cells

Scientists have developed a new way of counting labeled proteins in living cells that could become a standard and valuable tool in the field of biomedical research.

8 Aug 2024

How C. elegans uses smell to preemptively guard against pathogen attacks

Many organisms react to the smell of deadly pathogens by reflexively avoiding them. But a recent study from the University of California, Berkeley, shows that the nematode C. elegans also reacts to the odor of pathogenic bacteria by preparing its intestinal cells to withstand a potential onslaught.

7 Aug 2024

New treatment boosts pluripotent stem cell production in mice

Researchers at the Centre for Genomic Regulation (CRG) have discovered a treatment which accelerates the production and quality of pluripotent stem cells in mice.

7 Aug 2024

Breakthrough study highlights ATM activation by DNA single-strand breaks

New research from a team of genome scientists and DNA damage response experts breaks new ground in understanding the function of a protein currently limited in clinical trials for cancer treatments.

7 Aug 2024

Ribosomes in cells play a crucial role in protein folding

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature.

7 Aug 2024

Understanding the age gap in leukemia survival rates

Acute lymphoblastic leukemia (ALL) affects both children and adults, but children have better chances to be cured, with long-term survival rates over 85% compared to 50-75% in adults. Scientists at St. Jude Children's Research Hospital conducted a comprehensive study to understand the biological causes driving this difference. The work, published today in the Journal of Clinical Oncology, provides a blueprint for understanding B-cell acute lymphoblastic leukemia (B-ALL), the most common form of the disease.

7 Aug 2024

METRNL protein identified as key player in cancer progression

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins University School of Medicine and the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Finding ways to block the effects of METRNL signaling on tumor-infiltrating T cells may allow these immune cells to regain the energy necessary to eliminate tumors.

7 Aug 2024

The interplay of liver cancer stem cells and immune cells in tumor microenvironment

The complex dynamics between liver cancer stem cells (CSCs) and immune cells within the tumor microenvironment (TME) are central to the progression of liver cancer. These interactions are critical in creating an immunosuppressive setting that significantly impacts the response to immunotherapy. Liver CSCs, responsible for tumor initiation, metastasis, therapeutic resistance, and recurrence, exhibit heterogeneity and are characterized by various surface markers that contribute to their stemness and metastatic potential.

7 Aug 2024

Measuring blood plasma viscosity in COVID-19 using Brillouin light scattering spectroscopy

A research team led by MedUni Vienna has shown in a study that purely optical measurements of the viscosity of blood plasma may provide information about the severity and progression of COVID-19.

6 Aug 2024

Revolutionary real-time microscopy unveils secrets of motor protein behavior

A team led by Professor Seo Dae-ha of the Department of Physics and Chemistry at DGIST (President Lee Kun-woo) has developed new real-time microscopy technology and successfully observed the behavior of "motor proteins", which may hold the key to unraveling the efficient material transport strategy of cells.

2 Aug 2024

Advanced imaging techniques shed light on single cells

Every plant, animal, and person is a rich microcosm of tiny, specialized cells. These cells are worlds unto themselves, each with their own unique parts and processes that elude the naked eye.

2 Aug 2024

How machine learning is accelerating research in structural biology

For Lucas Farnung, there is no question more fascinating than how a single fertilized egg develops into a fully-functioning human.

2 Aug 2024

Cell Biology

McGill discovery offers hope for targeted stem cell treatments

Cell adhesion and starvation found to be key drivers of pattern formation in keratinocytes

New research identifies key protein complex in cellular quality control

Cell nuclei found to control tissue architecture in eye and brain development

Study reveals how light-activated macrophages increase their appetite for cancer cells

New histone tag discovery offers hope for myelin repair in neurodegenerative diseases

Mechanisms of tissue shape transformation revealed through fruit fly wing development

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

ProDOL revolutionizes protein quantification in living cells

How C. elegans uses smell to preemptively guard against pathogen attacks

New treatment boosts pluripotent stem cell production in mice

Breakthrough study highlights ATM activation by DNA single-strand breaks

Ribosomes in cells play a crucial role in protein folding

Understanding the age gap in leukemia survival rates

METRNL protein identified as key player in cancer progression

The interplay of liver cancer stem cells and immune cells in tumor microenvironment

Measuring blood plasma viscosity in COVID-19 using Brillouin light scattering spectroscopy

Revolutionary real-time microscopy unveils secrets of motor protein behavior

Advanced imaging techniques shed light on single cells

How machine learning is accelerating research in structural biology

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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