Cell Biology

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The surprising role of RNA in immune interactions

In a groundbreaking exploration of cell surface biology, Ryan Flynn has uncovered a surprising role for RNA outside the confines of the cell. Flynn's research, which focuses on the biology of cell surface RNA, led to the discovery that certain RNAs are chemically linked to glycans - complex carbohydrate polymers found on the cell surface.

22 Aug 2024

The critical role of PGK1 in Parkinson's disease

An enzyme called PGK1 has an unexpectedly critical role in the production of chemical energy in brain cells, according to a preclinical study led by researchers at Weill Cornell Medicine. The investigators found that boosting its activity may help the brain resist the energy deficits that can lead to Parkinson's disease.

21 Aug 2024

New discovery reveals how DNA regulates inheritance of disease mutations

University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.

21 Aug 2024

Hair follicles use unique sensor system to clean up dead cells

Billions of our cells die every day to make way for the growth of new ones. Most of these goners are cleaned up by phagocytes - mobile immune cells that migrate where needed to engulf problematic substances.

21 Aug 2024

Study reveals how avian flu adapts to mammalian cells

In recent years, public health measures, surveillance, and vaccination have helped bring about significant progress in reducing the impact of seasonal flu epidemics, caused by human influenza viruses A and B.

19 Aug 2024

Researchers identify possible candidates for multipotent stem cells in the sea anemone

The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists led by Ulrich Technau from the University of Vienna have now identified possible candidates for multipotent stem cells in the sea anemone for the first time.

19 Aug 2024

New Springer textbook provides a comprehensive overview of aging science

A new textbook provides an overview on the present understanding of aging - from the basic biology of aging to age-related diseases and to the role of lifestyle and the environment.

19 Aug 2024

Breakthrough in tissue engineering using bacteria

A research team at the Technical University of Denmark, led by Alireza Dolatshahi-Pirouz, has recently uncovered new ground in tissue engineering and cell therapy by harnessing the healing power of bacteria.

19 Aug 2024

PINNACLE AI model advances protein analysis in real-world contexts

A fish on land still waves its fins, but the results are markedly different when that fish is in water. Attributed to renowned computer scientist Alan Kay, the analogy is used to illustrate the power of context in illuminating questions under investigation.

16 Aug 2024

Understanding host immune responses through cell death pathways

A new review was published as the cover paper of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 15, entitled, "Types of cell death and their relations to host immunological pathways".

16 Aug 2024

Simplifying cell movement analysis with CellTracksColab

Studying cell migration is vital because it plays a crucial role in many biological processes, including immune response, wound healing, and cancer metastasis.

16 Aug 2024

Scientists discover brain's 'future map'

Researchers from the RIKEN Center for Brain Science (CBS) in Japan have discovered a region of the brain that encodes where an animal is planning to be in the near future. Linked to internal maps of spatial locations and past movements, activity in the newly discovered grid cells accurately predicts future locations as an animal travels around its environment. Published in Science on August 15th, 2024, the study helps explain how planned spatial navigation is possible.

16 Aug 2024

Exploring the mechanics of cell migration and growth

The National Institute of General Medical Sciences, a branch of the National Institutes of Health (NIH), has awarded Yubing Sun, associate professor of mechanical and industrial engineering at the University of Massachusetts Amherst, a $1.9 million Maximizing Investigators' Research Award to support the exploration of the fundamental principles behind the process that close gaps caused by injury or growth between cells. This research has the potential to push forward advances in our understanding of wound healing, cellular regeneration therapies and embryonic development.

16 Aug 2024

Quantum leap in single cell genomics: Scale Bio launches groundbreaking ‘100 Million Cell Challenge’ in collaboration with Ultima Genomics and NVIDIA

Scale Biosciences (Scale Bio), a leader in innovative and scalable single cell analysis solutions, today announced the launch of the “100 Million Cell Challenge,” a global initiative aimed at pushing the boundaries of single-cell genomics research.

16 Aug 2024

Understanding the complexities of epigenetic aging clocks in health research

A new editorial was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 14 on July 17, 2024, entitled, "Recalibrate concepts of epigenetic aging clocks in human health."

14 Aug 2024

DeNovix releases new CellDrop model and applications

DeNovix announces the release of the new CellDrop FLi Automated Cell Counter, the latest update to the popular CellDrop range.

From DeNovix Inc. 14 Aug 2024

New targets for improved cancer immunotherapy

In the past two decades, immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, showing promising results against various solid tumors. This study reviews recent developments in ICIs, focusing on new targets like T cell immunoreceptors with Ig and ITIM domains (TIGIT), T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), and lymphocyte activation gene-3 (LAG-3). These targets aim to overcome resistance mechanisms limiting the effectiveness of current therapies, such as anti-PD-1 and anti-CTLA-4. By identifying and developing these new ICIs, researchers hope to improve treatment outcomes and provide new therapeutic options for cancer patients.

14 Aug 2024

Researchers discover a novel pathway to wake up dormant neural stem cells

Scientists from Duke-NUS Medical School and the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) have discovered a novel pathway to wake up dormant neural stem cells, offering potential new therapies for neurodevelopmental disorders such as autism, learning disabilities, and cerebral palsy.

13 Aug 2024

New insights into lipid-induced senescence in dopaminergic neurons

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 14 on July 19, 2024, entitled, "Lipid accumulation drives cellular senescence in dopaminergic neurons."

13 Aug 2024

Mrc1 protein identified as key to maintaining cell identity during division

In a major scientific breakthrough, researchers have found that a protein called Mrc1 plays a crucial role in ensuring that cells keep their identity as they divide and grow.

13 Aug 2024