Cell Biology

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Artificial intelligence differentiates cancer cells and detects early viral infections

Researchers at the Centre for Genomic Regulation (CRG), the University of the Basque Country (UPV/EHU), Donostia International Physics Center (DIPC) and the Fundación Biofisica Bizkaia (FBB, located in Biofisika Institute) have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells.

27 Aug 2024

Study illuminates CDCA7's role in DNA methylation

DNA methylation, a process by which methyl groups are added to DNA molecules, is essential for the maintenance of DNA and the overall health of an organism.

27 Aug 2024

Novel approach reverses age-related cognitive decline

The authors investigate the physiological functions of Terc-53 by creating transgenic mice that overexpress this noncoding RNA. They observe that Terc-53 overexpression affects normal aging in mammals, contributing to cognitive decline and shortened lifespan.

27 Aug 2024

Stem cell study identifies unique glial contributions to multiple sclerosis

A team of scientists from The New York Stem Cell Foundation (NYSCF) Research Institute and Case Western Reserve University has created the largest reported collection of stem cell models from multiple sclerosis (MS) patients and used them to identify unique ways in which glia – integral support cells in the brain – contribute to the disease.

26 Aug 2024

Strength training triggers key mechanisms for cellular waste clearance

The elimination of damaged cell components is essential for the maintenance of the body's tissues and organs.

23 Aug 2024

Understanding nucleosome behavior during mitosis

Individual cells divide through a process called mitosis, during which the cell's copied DNA is separated between two resulting daughter cells.

23 Aug 2024

Temperature changes influence meiotic crossovers and chromosome organization in yeast

This study is led by Prof. Shunxin Wang (State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University) and Prof. Liangran Zhang (Advanced Medical Research Institute, Shandong University).

23 Aug 2024

Discovery of TLNRD1 protein could help better understand Cerebral Cavernous Malformations disease

Researchers have discovered a crucial protein, TLNRD1, that could help us better understand and treat Cerebral Cavernous Malformations (CCM) disease.

23 Aug 2024

The impact of stem cells on the epigenetic clock

How old are you, really? Your chronological age is the number of years you have been alive. Your biological age is how old your cells are which scientists believe may better assess one's age-related health and disease risk. People biologically age at different rates, depending on genetic and environmental factors, so that a person's chronological age does not necessarily match their biological age. In recent years, direct-to-consumer biological age tests have become increasingly accessible and popular as interest has increased in this nascent science.

23 Aug 2024

Immune cells' two-pronged approach to maintaining acetyl-CoA reserves

Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists.

23 Aug 2024

Ingenza announces partnership with Cellugy to investigate the potential of biofabricated cellulose

Industrial biotech specialist Ingenza is delighted to announce that it is collaborating with Cellugy to accelerate the development of its innovative platform for producing biofabricated cellulose.

From Ingenza Ltd 23 Aug 2024

Virginia Tech leads national initiative to predict and prevent future pandemics

Viruses like SARS-CoV-2 don't respect boundaries, moving between species and continents and leaving destruction as they go. Beating the next pathogen with pandemic potential means getting good at crossing borders ourselves - between fields of study, between research universities, and between scientists and the wider community.

23 Aug 2024

T cells influence memory of innate immune cells, research shows

Research from Radboud University Medical Center reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells.

22 Aug 2024

Study sheds light on the dual nature of cellular senescence

Scientists at Sanford Burnham Prebys and the La Jolla Institute for Immunology have revealed a new secret regarding senescence, a cellular state similar to sleep that is more likely to affect aged cells.

22 Aug 2024

Study shows frequent mitochondrial DNA insertion in the brain cells

As direct descendants of ancient bacteria, mitochondria have always been a little alien.

22 Aug 2024

Asgard archaea's role in eukaryotic immunity revealed

When you get infected with a virus, some of the first weapons your body deploys to fight it were passed down to us from our microbial ancestors billions of years ago.

22 Aug 2024

Research shows predation drives evolution of virulence in bacteria

Opportunistic pathogens are typically benign microbes that can sometimes cause infections in individuals with weakened immune systems or when they gain access to sterile areas of the body.

22 Aug 2024

Research unveils how HMGA2 regulates stress responses in stem cells

Kumamoto University researchers have made a groundbreaking discovery that sheds light on how the HMGA2 gene - an essential transcriptional activator involved in chromatin modification - regulates stress responses in hematopoietic stem cells (HSCs), thereby enhancing blood cell production recovery.

22 Aug 2024

mRNA therapy shows promise for maple syrup urine disease

Researchers from the University of Pennsylvania, Perelman School of Medicine, Gene Therapy Program, and Moderna, have shown that repeated administration of lipid nanoparticle-encapsulated mRNA therapy significantly extended survival and reduced serum leucine levels in a mouse model of maple syrup urine disease (MSUD).

22 Aug 2024

The surprising role of RNA in immune interactions

In a groundbreaking exploration of cell surface biology, Ryan Flynn has uncovered a surprising role for RNA outside the confines of the cell. Flynn's research, which focuses on the biology of cell surface RNA, led to the discovery that certain RNAs are chemically linked to glycans - complex carbohydrate polymers found on the cell surface.

22 Aug 2024