Cell Biology

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Could a blood test predict how cancer spreads in children?

Traditionally, we use biopsies to try to predict how cancer spreads. There are a number of molecular markers that are used, but biopsy is a limited approach. Now, the current trend is to use liquid biopsy, which is basically a blood sample.

21 Jun 2017

MIT biologists identify how the immune system eliminates genetically imbalanced cells

Most living cells have a defined number of chromosomes: Human cells, for example, have 23 pairs. As cells divide, they can make errors that lead to a gain or loss of chromosomes, which is usually very harmful.

20 Jun 2017

Francis Crick Institute selects Livecyte cell analysis system from Phasefocus

Phasefocus provides a range of products and services based on its proprietary Ptychographic Quantitative Phase Imaging (QPI) technology to provide a wide range of analytical applications including label-free cell imaging and quantitative electron phase microscopy. Here, they report on the Light Microscopy Science Technology Platform at the Francis Crick Institute’s selection of the Livecyte® label-free cell analysis system.

From Phase Focus Limited 19 Jun 2017

Mutations identified that enable human transmission of avian flu

A systematic mutation analysis has shown that changes in just three amino acids of the avian influenza H7N9 virus receptor binding protein confers specificity for human cells.

16 Jun 2017

Developing synthetic mediums for growing organoids

Organoids are bits of tissue grown in vitro, in a near-physiological 3D setting. The particularity consists in the fact that organoids retain features of the patient they are derived from, even when cultured outside of the human body. This is very different from what traditional, conventional cell culture has been able to do over the past 50 years or so.

13 Jun 2017

Salk scientist uses mathematical framework to better understand how cell types divide work

Despite advances in neuroscience, the brain is still very much a black box--no one even knows how many different types of neurons exist.

7 Jun 2017

Molecular biologists identify enzyme that activates and ‘supercharges’ cellular machinery

St. Jude Children's Research Hospital molecular biologists have identified an enzyme that activates and "supercharges" cellular machinery that controls how cells become specialized cells in the body.

7 Jun 2017

New protocol offers faster and more effective way to obtain astrocytes from stem cells

Neurons have long enjoyed the spotlight in neuroscience--and for good reason: they are incredibly important cellular actors. But, increasingly, star-shaped support cells called astrocytes are being seen as more than bit players in the brain's rich pageant.

6 Jun 2017

Scientists reveal 12-hour autonomous biological clock that coordinates bodily functions

Some bodily activities, sleeping, for instance, mostly occur once every 24 hours; they follow a circadian rhythm. Other bodily functions, such as body temperature, cognitive performance and blood pressure, present an additional 12-hour cycle, but little is known about the biological basis of their rhythm.

6 Jun 2017

Scientists locate crucial off-switch for central cell control

As the cell's molecular control center, the mTor kinase regulates cellular metabolism, growth and division. However, in cells affected by pathological change, the regulation goes array.

2 Jun 2017

Study unravels mystery of how nerve cells are damaged in neurodegenerative diseases

A new study has uncovered a molecular mechanism in the prion protein, a protein responsible for neurodegenerative diseases, which may explain why nerve cells degenerate in these disorders.

25 May 2017

Leica introduces new DMi8 S solution for fast, versatile microscopic imaging of living cells

Leica introduces the DMi8 S, a new complete solution designed to give researchers the ultimate tool for fast, versatile microscopic imaging of living cells allowing scientists to find, observe and interact with living cells like never before.

From Leica Microsystems GmbH 25 May 2017

Feinstein Institute honors Sir Paul Nurse with Cerami Award for cancer research

Northwell Health's Feinstein Institute for Medical Research and Molecular Medicine announced today that the seventh Anthony Cerami Award in Translational Medicine will be awarded to Sir Paul Nurse, PhD, director of The Francis Crick Institute.

24 May 2017

U-M research reveals important clues about invasion of polyomaviruses

Every cell in our body runs like a tiny factory that makes specialized products, using the carefully guarded instructions kept in the CEO's office.

24 May 2017

Research into cellular senescence may lead to new ways of treating age-related disorders

One of the things that happens to our bodies as we age is that certain cells start to accumulate. So-called senescent cells – cells that "retire" and stop dividing but refuse to die – are always present, and they even serve some important functions, such as in wound repair.

18 May 2017

Researchers discover innovative way to produce hematopoietic stem cells

A study published on May 17 in Nature, discovers an innovative method to produce infinite supply of healthy blood cells from the readily available cells that line blood vessels. This achievement by the researchers at Weill Cornell Medicine marks the first time that any research group has generated such blood-forming stem cells.

18 May 2017

Tumor mutation load in patient's biopsy varies by age and type of cancer

A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that the tumor mutation load, or TML, in a patient's cancer biopsy varied by age and the type of cancer, along with several other factors.

18 May 2017

Mother cells pass on DNA damage to offspring, study shows

A new University of Colorado Boulder study has shown that some dividing human cells are "kicking the can down the road," passing on low-level DNA damage to offspring, causing daughter cells to pause in a quiescent, or dormant, state previously thought to be random in origin.

17 May 2017

Scientists unravel mystery of T cell signaling process vital to immune response

The immune system cells known as T cells play a central role in the body's ability to fight infections and cancer. For decades, however, details of the molecular signaling process that leads to T cell activation have remained a mystery.

16 May 2017

Breast cancer cells undergo stiffening state prior to becoming malignant, study shows

A study published now on Nature Communications shows that breast cancer cells undergo a stiffening state prior to acquiring malignant features and becoming invasive.

16 May 2017

Cell Biology

Could a blood test predict how cancer spreads in children?

MIT biologists identify how the immune system eliminates genetically imbalanced cells

Francis Crick Institute selects Livecyte cell analysis system from Phasefocus

Mutations identified that enable human transmission of avian flu

Developing synthetic mediums for growing organoids

Salk scientist uses mathematical framework to better understand how cell types divide work

Molecular biologists identify enzyme that activates and ‘supercharges’ cellular machinery

New protocol offers faster and more effective way to obtain astrocytes from stem cells

Scientists reveal 12-hour autonomous biological clock that coordinates bodily functions

Scientists locate crucial off-switch for central cell control

Study unravels mystery of how nerve cells are damaged in neurodegenerative diseases

Leica introduces new DMi8 S solution for fast, versatile microscopic imaging of living cells

Feinstein Institute honors Sir Paul Nurse with Cerami Award for cancer research

U-M research reveals important clues about invasion of polyomaviruses

Research into cellular senescence may lead to new ways of treating age-related disorders

Researchers discover innovative way to produce hematopoietic stem cells

Tumor mutation load in patient's biopsy varies by age and type of cancer

Mother cells pass on DNA damage to offspring, study shows

Scientists unravel mystery of T cell signaling process vital to immune response

Breast cancer cells undergo stiffening state prior to becoming malignant, study shows

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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