Disease/Infection News

RSS

Study provides resource for investigating diabetes-linked transcription factors

Scientists have generated a comprehensive map of the gene targets regulated by the transcription factors HNF4A and HNF1A in human pancreatic beta cells and liver cells. Published in the journal Nature Communications, the study revealed common and tissue-specific molecular pathways regulated by HNF4A and HNF1A, two proteins that possess important functions governing the development and function of the pancreas and liver.

26 Jun 2024

AI-powered wristband or fingertip clip may revolutionize sleep apnea diagnosis

West Virginia University researchers will put a sleep apnea detection device at the fingertips or wrists of patients facilitating early diagnosis and treatment of the disease with support from a National Science Foundation grant.

26 Jun 2024

Open-source platform enables high-definition spatial transcriptomics

An open-source platform developed by researchers in Nikolaus Rajewsky's lab at the Max Delbrück Center creates molecular maps from patient tissue samples with subcellular precision, enabling detailed study and potentially enhancing routine clinical pathology. The study was published in "Cell."

25 Jun 2024

MicroRNAs shed light on aggressive youthful type 2 diabetes

Type 2 diabetes in young people ages 10 to19 has more than doubled in the past 20 years, yet it remains difficult for physicians to predict who will be diagnosed and who will improve with treatment. A newly published study from the University of Oklahoma shows that measuring the circulating abundance of microRNAs – which affect insulin-producing beta cells in the pancreas – is likely as effective as measuring the level of sugar in the blood for determining how a young person with the condition will fare.

25 Jun 2024

Study links gene regulation to allergic airway inflammation

Asthma patients experience respiratory distress due to allergens like house dust mites or pollen. However, the various triggers for asthma share a common pathway involving the release of proteins called type-2 cytokines by Type-2 helper T (Th2) cells and group-2 innate lymphoid cells (ILC2s). Both Th2 and ILC2 require high amounts of GATA-binding protein 3 (GATA3) for their maturation.

25 Jun 2024

Innovative fingerprint technique detects TB antibiotics with high accuracy

A fingerprint may soon be all a doctor needs to check whether tuberculosis patients are taking their antibiotics – thanks to a new study led by the University of Surrey.

24 Jun 2024

Study reveals cannabis and tobacco users face higher COVID-19 hospitalization and adverse outcomes

Researchers found that cannabis and tobacco use significantly increase the risk of hospitalization and adverse outcomes in COVID-19 patients, even when controlling for other factors.

24 Jun 2024

Study reveals early immune responses to SARS-CoV-2, offering insights for future COVID-19 treatments

Researchers analyzed early immune responses to SARS-CoV-2 using single-cell multi-omics, revealing key cellular states associated with different infection outcomes.

24 Jun 2024

Brazilian researchers identify possible biomarkers associated with recurrence of vivax malaria

The most common type of malaria in Brazil is caused by the parasite Plasmodium vivax. Although vivax malaria is milder than the variant caused by P. falciparum, the ability of P. vivax to produce dormant forms in the host's liver that can be reactivated months after the end of treatment makes it very hard to control.

24 Jun 2024

Will it soon be possible for doctors to use AI to detect and diagnose cancer?

Researchers developed binary and multiclass machine learning models to distinguish cancer from non-cancerous tissue samples.

24 Jun 2024

Healthy gut bacteria linked to fewer infection-related hospitalizations, study finds

The association between gut microbiota composition and risk of infection-related hospitalization.

24 Jun 2024

New study warns of potential pandemic risk from α-H1N2 swine flu virus

The α-H1N2 influenza virus in swine poses a higher pandemic risk due to its ability to evade human immunity and transmit between species, highlighting the need for vigilant monitoring.

23 Jun 2024

New fingerprint test could ensure TB patients are taking their antibiotics

Scientists can now detect antibiotics in your fingerprints – aiding the fight against drug-resistant TB.

22 Jun 2024

Low-cost CRISPR-based paper strip test offers rapid influenza diagnosis

Fewer than one percent of people who get the flu every year get tested, in part because most tests require trained personnel and expensive equipment.

21 Jun 2024

Cannabis use tied to increased risk of severe COVID-19

As the deadly disease that came to be known as COVID-19 started spreading in late 2019, scientists rushed to answer a critical question: Who is most at risk?

21 Jun 2024

How micro- and nanoplastics may worsen non-communicable diseases

Researchers review and assess the potential exacerbation of non-communicable diseases by micro- and nanoplastics.

21 Jun 2024

Can cocoa lower your heart disease risk?

Researchers review the effects of cocoa consumption on the risk of cardiovascular disease.

21 Jun 2024

Human fleas found to be a culprit in plague outbreaks

The plague might be most commonly associated with the devastating European pandemic of the 1300s known as the "Black Death".

21 Jun 2024

Research finds stem-like T cells are associated with pathogenesis in ulcerative colitis

Researchers investigated whether stem-like T lymphocytes are involved in ulcerative colitis pathogenesis.

21 Jun 2024

WHO commends Chad for eradicating sleeping sickness

The World Health Organization (WHO) congratulates Chad for having eliminated the gambiense form of human African trypanosomiasis, also known as sleeping sickness, as a public health problem.

20 Jun 2024