Drug Discovery & Pharmaceuticals

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New small molecules offer promising new way to treat autoinflammatory diseases

EPFL scientists have discovered two small-molecule compound series that can effectively block a central pathway of the innate immune system, offering a promising new way for treating autoinflammatory diseases.

4 Jul 2018

Innovative synthetic technique opens door to new world of cutting-edge medicinal compounds

In pharmacology, not all molecular structures are created equal. Some frameworks are overrepresented in nature, making them especially attractive to scientists on the hunt for more effective drugs.

4 Jul 2018

Lonza launches new website to support bioresearch, drug discovery scientists

Lonza Bioscience is inviting visitors to explore its new dedicated website: bioscience.lonza.com. Filled with detailed application and product information, the website has been designed to support the work of scientists across the bioresearch, drug discovery and pharmaceutical manufacturing fields.

From Lonza 3 Jul 2018

New medication may treat chemotherapy, radiotherapy-induced oral mucositis

Researchers from the University of Granada have developed new medication which could help to treat and prevent chemotherapy and radiotherapy-induced oral mucositis in head and neck cancer patients.

30 Jun 2018

URI researchers working to develop novel medication to treat alcohol use disorder

Alcohol abuse is among the leading causes of preventable death in the United States, killing more than 88,000 people a year, according to the Centers for Disease Control.

28 Jun 2018

DNA methylation predicts survival outcome in patients with glioma

A new study has shown that survival rates among patients with glioma double if the tumor carries a methylated MGMT gene.

28 Jun 2018

LUMICKS partners with AstraZeneca, University of Cambridge to establish new 'Center of Excellence for Dynamic Single-Molecule Analysis for Accelerated Drug Discovery and Biology'

The center will be based around LUMICKS’ C-Trap™ optical tweezers–fluorescence microscope, which for the first time enables real-time observation and probing of biomolecular interactions. The approach will be pioneered in several pharmacology and biology assays with the aim of accelerating the discovery of potential new drugs.

From Lumicks 28 Jun 2018

Scientists create microparticles that mimic human T cells

Researchers have developed synthetic microparticles with properties and behaviors that closely mimic human T cells.

27 Jun 2018

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

AbbVie , a research-based global biopharmaceutical company, and Calibr, a nonprofit drug discovery division of Scripps Research, today announced a collaboration to develop T-cell therapies aimed primarily at cancer, including solid tumors.

25 Jun 2018

Researchers discover drug compound that inhibits movement of cancer cells

Fighting cancer means killing cancer cells. However, oncologists know that it's also important to halt the movement of cancer cells before they spread throughout the body.

22 Jun 2018

Minakem's new high-class production facility extends capacity to develop and manufacture HPAPI compounds

Minakem, the CDMO division of Minafin, specialized in custom development and manufacturing of building blocks, GMP intermediates and Active Pharmaceutical Ingredients, today announces it is in the final qualification run to open a new closed-controlled environment high containment production facility in August.

22 Jun 2018

Chemists find new way to make enzymes do a non-natural reaction

Princeton chemists have found a way to make a naturally occurring enzyme take on a new, artificial role, which has significant implications for modern chemistry, including pharmaceutical production.

22 Jun 2018

Scientists discover the molecular trigger of necroptosis

Researchers have uncovered a trigger for an immune-related cell death pathway called necroptosis. The discovery could be used to develop new treatments for cancer and immune disorders.

21 Jun 2018

Protein Data Bank at Rutgers impacts research, education and drug discovery

When Jimmy Carter was diagnosed with end-stage metastatic melanoma in 2015, he began taking a drug developed in part using 3D molecular data.

21 Jun 2018

Distek, Inc. launches new product that extends the capabilities of the symphony 7100

Distek, Inc. announced today the release of their small volume conversion kit for the symphony 7100 bathless dissolution tester,

20 Jun 2018

Microbiotica partners with University of Adelaide to develop defined bacterial product for ulcerative colitis

Microbiotica, a leading player in microbiome-based therapeutics, today announced that it has entered into an agreement with University of Adelaide as part of its program to develop a defined bacterial product for ulcerative colitis (UC). Financial details have not been disclosed.

19 Jun 2018

Chemists invent new method for remote chiral induction

Chemists at Scripps Research have addressed one of the most formidable challenges in synthetic chemistry by inventing a method for "enantioselective remote meta-CH activation," which enables the making of chiral molecules that were previously difficult or impossible to synthesize.

19 Jun 2018

Scientists could build better drugs by learning from bacteria-derived molecules

Bacteria found in soil may harbor a potential game-changer for drug design. A new study by Scripps Research, published today in Nature Communications, suggests scientists could build better drugs by learning from bacteria-derived molecules called thiocarboxylic acids.

19 Jun 2018

Novel compound as effective as FDA-approved antibiotics for treating deadly infections

Purdue University researchers have identified a new compound that in preliminary testing has shown itself to be as effective as antibiotics approved by the Food and Drug Administration to treat life-threatening infections while also appearing to be less susceptible to bacterial resistance.

18 Jun 2018

Award granted to Neem Biotech to develop antimicrobial intervention for chronic lung infections

Neem are working on a novel approach to antimicrobial resistance, which involves preventing the formation of and disrupts mature biofilms that are produced by bacteria such as Pseudomonas aeruginosa and Staphylococcus aureus.

From Neem Biotech 18 Jun 2018

Drug Discovery & Pharmaceuticals

New small molecules offer promising new way to treat autoinflammatory diseases

Innovative synthetic technique opens door to new world of cutting-edge medicinal compounds

Lonza launches new website to support bioresearch, drug discovery scientists

New medication may treat chemotherapy, radiotherapy-induced oral mucositis

URI researchers working to develop novel medication to treat alcohol use disorder

DNA methylation predicts survival outcome in patients with glioma

LUMICKS partners with AstraZeneca, University of Cambridge to establish new 'Center of Excellence for Dynamic Single-Molecule Analysis for Accelerated Drug Discovery and Biology'

Scientists create microparticles that mimic human T cells

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

Researchers discover drug compound that inhibits movement of cancer cells

Minakem's new high-class production facility extends capacity to develop and manufacture HPAPI compounds

Chemists find new way to make enzymes do a non-natural reaction

Scientists discover the molecular trigger of necroptosis

Protein Data Bank at Rutgers impacts research, education and drug discovery

Distek, Inc. launches new product that extends the capabilities of the symphony 7100

Microbiotica partners with University of Adelaide to develop defined bacterial product for ulcerative colitis

Chemists invent new method for remote chiral induction

Scientists could build better drugs by learning from bacteria-derived molecules

Novel compound as effective as FDA-approved antibiotics for treating deadly infections

Award granted to Neem Biotech to develop antimicrobial intervention for chronic lung infections

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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