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Majority of people in the UK would consider taking part in a clinical trial, survey reveals

The majority of people in the UK (68%) would consider taking part in a clinical trial, it has been revealed today (19 May), while half of Brits would also be willing to take part in an early phase clinical trial.

18 May 2023

Clinical trial shows efficacy and safety of brepocitinib for treating adults with psoriatic arthritis

Brepocitinib is an oral drug that inhibits certain enzymes involved in inflammation - called tyrosine kinase 2 and Janus kinase 1 - and is being tested for the treatment of several immunological diseases.

17 May 2023

Nemours Children's Health selected to conduct first gene therapy clinical trial for Morquio A syndrome

As part of the Foundation for the National Institutes of Health Accelerating Medicines Partnership Bespoke Gene Therapy Consortium, Nemours Children's Health has been chosen to conduct a first-of-its-kind gene therapy clinical trial for Morquio A syndrome.

16 May 2023

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

A new international study published in Nature Medicine and presented as a late-breaking abstract at the American Association of Neurological Surgeons annual conference, shows great promise for patients with glioblastoma.

15 May 2023

Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

A clinical trial of an experimental universal influenza vaccine developed by researchers at the National Institute of Allergy and Infectious Diseases' (NIAID) Vaccine Research Center (VRC), part of the National Institutes of Health, has begun enrolling volunteers at Duke University in Durham, North Carolina.

15 May 2023

Cyclical estrogen/anti-estrogen therapy could be a promising strategy to treat metastatic ER+ breast cancer

Advanced or metastatic estrogen receptor-positive (ER+) breast cancer is commonly treated with drugs that block the estrogen receptor.

15 May 2023

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto.

15 May 2023

Study aims to optimize radiotherapy treatment for patients with anal cancer

Reducing the dose and duration of radiotherapy treatments for anal cancer may result in fewer side effects, recent clinical trial results have shown.

15 May 2023

First-in-human clinical trial tests experimental oral drug for removing radioactive contaminants

A first-in-human clinical trial of an experimental oral drug for removing radioactive contaminants from inside the body has begun.

15 May 2023

The safety and efficacy of FINLAY-FR-2/1A, a new protein-based COVID-19 vaccine

Research paper reports the results of a phase 3 clinical trial evaluating the efficacy and safety of the FINLAY-FR-2 and FINLAY-FR-1A vaccines in Iranian adults.

7 May 2023

Combination treatment shows promise for aggressive subtype of non-Hodgkin lymphoma

Nearly 90 percent of patients with an aggressive subtype of non-Hodgkin lymphoma had their cancer go into remission in a small phase 2 clinical trial testing a treatment aimed at making chemotherapy more effective, according to Weill Cornell Medicine and NewYork-Presbyterian investigators.

5 May 2023

High-dose drug for erectile dysfunction improves long-term blood sugar levels in diabetes patients

A small group of patients with type 2 diabetes significantly improved their long-term blood sugar levels when treated with high-dose tadalafil, a medication used to treat erectile dysfunction.

5 May 2023

Eli Lilly trial reveals Alzheimer's drug that significantly slows cognitive decline

Study examined the safety and efficacy of the study drug donanemab in participants with early Alzheimer's disease (AD).

4 May 2023

Researchers report positive results from Phase 2 clinical trial of investigational treatment against long COVID fatigue

Researchers from the University of Oxford have reported findings from a Phase 2 clinical trial investigating the efficacy of an investigational treatment against long COVID fatigue.

3 May 2023

Novel immunotherapy appears to be safe, well tolerated by children with relapsed brain tumors

The first in-human-study of a new immunotherapy that blocks a natural enzyme tumors commandeer for their protection was well tolerated by children with relapsed brain tumors and enabled many to have unexpected months of a more normal life, researchers say.

25 Apr 2023

Antibody combination strongly protects high-risk people with early COVID-19 symptoms, trial shows

A treatment combining two antibodies against the coronavirus SARS-CoV-2 strongly protected high-risk people with early COVID-19 symptoms from hospitalization and death in an international Phase 2/3 clinical trial conducted in the first half of 2021 and co-led by researchers at Weill Cornell Medicine and NewYork-Presbyterian.

20 Apr 2023

First-in-human clinical study begins investigating the duoCAR T-cell therapy for treatment of HIV

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Drug Trial News

Majority of people in the UK would consider taking part in a clinical trial, survey reveals

Clinical trial shows efficacy and safety of brepocitinib for treating adults with psoriatic arthritis

Nemours Children's Health selected to conduct first gene therapy clinical trial for Morquio A syndrome

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

Cyclical estrogen/anti-estrogen therapy could be a promising strategy to treat metastatic ER+ breast cancer

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Study aims to optimize radiotherapy treatment for patients with anal cancer

First-in-human clinical trial tests experimental oral drug for removing radioactive contaminants

The safety and efficacy of FINLAY-FR-2/1A, a new protein-based COVID-19 vaccine

Combination treatment shows promise for aggressive subtype of non-Hodgkin lymphoma

High-dose drug for erectile dysfunction improves long-term blood sugar levels in diabetes patients

Eli Lilly trial reveals Alzheimer's drug that significantly slows cognitive decline

Researchers report positive results from Phase 2 clinical trial of investigational treatment against long COVID fatigue

Novel immunotherapy appears to be safe, well tolerated by children with relapsed brain tumors

Antibody combination strongly protects high-risk people with early COVID-19 symptoms, trial shows

First-in-human clinical study begins investigating the duoCAR T-cell therapy for treatment of HIV

GW one of 18 clinical trial sites across the United States testing monkeypox vaccine in adolescents

SWOG investigators report results from DART clinical trial of immunotherapy combination for rare gynecologic cancers

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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