Genomics

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Researchers recommend strategies for improving the accuracy of polygenic risk scores

As the consumer genetics industry rapidly expands, more and more people are turning to DNA-based services to learn their risk of developing a wide range of diseases.

5 Dec 2020

CRISPR-based test could provide rapid, low-cost testing to help control COVID-19 spread

Imagine swabbing your nostrils, putting the swab in a device, and getting a read-out on your phone in 15 to 30 minutes that tells you if you are infected with the COVID-19 virus.

5 Dec 2020

Researchers develop a promising fix to CRISPR-Cas9's unwanted changes problem

A group of researchers developed a promising fix to CRISPR-Cas9's problem with unwanted genetic changes using a method that allows them to turn off gene-editing until it reaches key cell cycle phases where more accurate repairs are likely to happen.

4 Dec 2020

New CRISPR-Cas9 variant improves efficiency of gene editing tool

Using a new variant to repair DNA will improve both safety and effectiveness of the much-touted CRISPR-Cas9 tool in genetic research, Michigan Medicine researchers say.

3 Dec 2020

Multiple gene substitution in tomatoes helps improve yield, nutrient content

Cooked, fresh, sun-dried, or juiced, whichever way you prefer them, tomatoes are arguably one of the most versatile fruits on the planet--and yes, despite mainly being used in savory dishes, tomatoes really are a fruit.

2 Dec 2020

SARS-CoV-2's microRNAs may have promoted its jump to humans

A new study uses machine learning to explore the small microRNAs (or miRNAs) of SARS-CoV-2 that may determine the virus's ability to successfully infect humans by altering the course of transcriptional events.

1 Dec 2020

Molecular techniques explain how the Great Barrier Reef corals survived tough conditions

In a ground-breaking new study, scientists used innovative molecular techniques to explain how corals on the east coast of Australia survived previous tough conditions--enabling the Great Barrier Reef to become the vast reef it is today.

1 Dec 2020

Researchers find way for customized programming of human stem cells

Induced pluripotent stem cells (iPS) have the potential to convert into a wide variety of cell types and tissues for drug testing and cell replacement therapies. However, the "recipes" for this conversion are often complicated and difficult to implement.

30 Nov 2020

New selective method for DNA sequencing could enable quicker diagnosis of rare diseases

Scientists at the University of Nottingham have made a major breakthrough in genome sequencing, which will enable them to search for the underlying causes of diseases in human DNA quicker than ever before.

30 Nov 2020

Scientists use 3D mapping techniques to unravel mystery of blood stem cells

Princess Margaret scientists have revealed how stem cells are able to generate new blood cells throughout our life by looking at vast, uncharted regions of our genetic material that hold important clues to subtle biological changes in these cells.

25 Nov 2020

Research sheds new light on how the CRISPR immune system evolved

With new insights into how the genetic tool CRISPR - which allows direct editing of our genes - evolved and adapted, we are now one step closer to understanding the basis of the constant struggle for survival that takes place in nature. The results can be used in future biotechnologies.

25 Nov 2020

Study: None of the SARS-CoV-2 mutations appear to increase transmissibility in humans

None of the mutations currently documented in the SARS-CoV-2 virus appear to increase its transmissibility in humans, according to a study led by UCL researchers.

25 Nov 2020

Study reveals a gene responsible for anthraquinone synthesis in plants

Anthraquinones are a class of naturally occurring compounds prized for their medicinal properties, as well as for other applications, including ecologically friendly dyes.

25 Nov 2020

Mother's protein found to be involved in genomic imprinting process

Mothers leave their mark on their children in many ways - and Australian researchers have discovered a protein called SMCHD1 is involved in this 'imprinting' process.

24 Nov 2020

New findings could pave the way for more effective, safer and cheaper gene therapy

In a promising advance for affordable, personalized medicine, researchers have used metal-organic frameworks to successfully deliver the genetic snipping tool CRISPR/Cas9 into human cancer cells.

20 Nov 2020

Specific bacterial sRNA plays key role in symbiosis between Vibrio fischeri and squid

Bacteria living symbiotically within the Hawaiian bobtail squid can direct the host squid to change its normal gene-expression program to make a more inviting home, according to a new study published in PLoS Biology by researchers at the University of Hawai'i (UH) at Mānoa School of Ocean and Earth Science and Technology (SOEST).

20 Nov 2020

Researchers identify CLCN6 as disease gene for severe lysosomal neurodegenerative disorder

A mutation in the CLCN6 gene is associated with a novel, particularly severe neurodegenerative disorder. Scientists from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie and the Max Delbrück Center für Molekulare Medizin, together with an international team of researchers, have now analyzed the effect of a point mutation that was found in three unrelated affected children.

19 Nov 2020

Genomics

Researchers recommend strategies for improving the accuracy of polygenic risk scores

CRISPR-based test could provide rapid, low-cost testing to help control COVID-19 spread

Researchers develop a promising fix to CRISPR-Cas9's unwanted changes problem

New CRISPR-Cas9 variant improves efficiency of gene editing tool

Multiple gene substitution in tomatoes helps improve yield, nutrient content

SARS-CoV-2's microRNAs may have promoted its jump to humans

Molecular techniques explain how the Great Barrier Reef corals survived tough conditions

Researchers find way for customized programming of human stem cells

New selective method for DNA sequencing could enable quicker diagnosis of rare diseases

Scientists use 3D mapping techniques to unravel mystery of blood stem cells

Research sheds new light on how the CRISPR immune system evolved

Study: None of the SARS-CoV-2 mutations appear to increase transmissibility in humans

Study reveals a gene responsible for anthraquinone synthesis in plants

Mother's protein found to be involved in genomic imprinting process

New findings could pave the way for more effective, safer and cheaper gene therapy

Specific bacterial sRNA plays key role in symbiosis between Vibrio fischeri and squid

Researchers identify CLCN6 as disease gene for severe lysosomal neurodegenerative disorder

Research shows sexual lineage plays crucial role in transgenerational plasticity

Researchers use proteogenomics to better understand the biological complexity of breast cancer

Finding ways to mitigate food allergies at the source

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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