Genomics

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New dual-plasmid editing system for DNA-based information rewriting in vivo

DNA-based information is a new interdisciplinary field linking information technology and biotechnology.

5 Aug 2022

Tibbiyah-BGI Almanahil JV will provide highly specialized clinical laboratory testing services

Arabian International Healthcare Holding Company ("Tibbiyah"), a leading integrated healthcare solutions provider in Saudi Arabia, today announced a definitive Joint Venture Agreement with BGI Almanahil Health for Medical Services, a subsidiary company of BGI Health (HK) Co., Ltd, in the formation and operation of a limited liability company to be called Saudi Advanced Medical Lab LIMITED ("SAMLL") in Saudi Arabia.

5 Aug 2022

Baboons at Amboseli offer clues to the costs of the hybridization, study says

New genetic analyses of wild baboons in southern Kenya reveals that most of them carry traces of hybridization in their DNA. As a result of interbreeding, about a third of their genetic makeup consists of genes from another, closely-related species.

5 Aug 2022

Research highlights the crucial role of other living primates as models for understanding human evolution

A new study based in Africa reveals hidden selection against interspecies breeding in wild baboon species in a strikingly similar way to what has been described for archaic hominins. The findings, based on coupled genomic and long-term field data, highlight the crucial role of other living primates as models for understanding human evolution, particularly for phenomena that are impossible to study in our lineage alone.

5 Aug 2022

Study reveals the effects of an atypical mode of chromosome arrangement on genome architecture and evolution

A research team led by André Marques at the Max Planck Institute for Plant Breeding Research in Cologne, Germany, has uncovered the profound effects of an atypical mode of chromosome arrangement on genome organization and evolution.

4 Aug 2022

Researchers uncover genomic characteristics of breast cancers associated with PTEN hamartoma tumor syndrome

Cleveland Clinic researchers have uncovered genomic characteristics of breast cancers associated with PTEN hamartoma tumor syndrome (PHTS) that differentiate them from sporadic breast cancers.

4 Aug 2022

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Mitochondria are organelles found within most cells, best known for generating the chemical energy required to power cellular functions.

4 Aug 2022

Analysis of monkeypox virus genomes suggests that it spread early and cryptically

A new study reports the identification of a cluster of monkeypox virus A.2 lineage genomes.

3 Aug 2022

Study: Genes involved in coronary heart disease may be nearly the same for everyone

The genes involved in coronary heart disease, the most common form of heart disease, appear to be nearly the same for everyone, according to a VA study.

3 Aug 2022

UCI researchers develop novel test that detects specific SARS-CoV-2 variants with 100% accuracy

University of California, Irvine researchers have developed a COVID-19 test that detects and identifies specific SARS-CoV-2 variants with 100% accuracy.

3 Aug 2022

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

Investigators from Cedars-Sinai Cancer have identified genetic signatures that could predict whether tumors in patients with bladder and other cancers will respond to immunotherapy.

3 Aug 2022

'RNA fishing' technique identifies several proteins involved in the progression of melanoma

Researchers at the Centre for Genomic Regulation have identified several proteins involved in the progression of melanoma, the deadliest form of skin cancer.

3 Aug 2022

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

A fruit fly genome is not a just made up of fruit fly DNA – at least for one fruit fly species. New research from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) shows that one fruit fly species contains whole genomes of a kind of bacteria, making this finding the largest bacteria-to-animal transfer of genetic material ever discovered. The new research also sheds light on how this happens.

3 Aug 2022

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

A multidisciplinary study led by Vanja Nagy (LBI-RUD/CeMM/Medical University of Vienna) and Josef Penninger (UBC/IMBA) characterized a novel gene, known as FIBCD1, to be likely causative of a new and rare neurodevelopmental disorder.

2 Aug 2022

IRB Barcelona researchers discover genetic drivers of clonal hematopoiesis

Clonal hematopoiesis is a biological process in which a blood stem cell (the population that gives rise to a variety of blood cell types) acquires an advantageous mutation and outgrows neighboring cells.

2 Aug 2022

Asexual reproduction results in more harmful genetic mutations than sexual reproduction

A team led by biologists at The University of Texas at Arlington has published a study supporting the theory that species that reproduce asexually have more harmful genetic mutations than those utilizing sexual reproduction.

1 Aug 2022

SLAS; Connecting the Life Sciences to Accelerate Research

As part of our SLAS Europe 2022 coverage, we speak to Vicki Louise, CEO of SLAS, about the importance of collaboration in accelerating life sciences research.

From Society for Laboratory Automation and Screening (SLAS) 1 Aug 2022

Study shows cellular differences in brain development between modern humans and Neanderthals

Dresden and Leipzig researchers find that stem cells in the developing brain of modern humans take longer to divide and make fewer errors when distributing their chromosomes to their daughter cells, compared to those of Neanderthals.

29 Jul 2022

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

NSF grant awarded to Zhang for producing muscle fiber with synthetic biology approach

Fuzhong Zhang, professor of energy, environmental and chemical engineering at the McKelvey School of Engineering, has developed a synthetic biology platform to produce muscle fibers that are strong, tough and can absorb energy in ways very similar to the real thing.

29 Jul 2022

Genomics

New dual-plasmid editing system for DNA-based information rewriting in vivo

Tibbiyah-BGI Almanahil JV will provide highly specialized clinical laboratory testing services

Baboons at Amboseli offer clues to the costs of the hybridization, study says

Research highlights the crucial role of other living primates as models for understanding human evolution

Study reveals the effects of an atypical mode of chromosome arrangement on genome architecture and evolution

Researchers uncover genomic characteristics of breast cancers associated with PTEN hamartoma tumor syndrome

Mitochondrial DNA mutations are associated with an increased risk of atherosclerosis

Analysis of monkeypox virus genomes suggests that it spread early and cryptically

Study: Genes involved in coronary heart disease may be nearly the same for everyone

UCI researchers develop novel test that detects specific SARS-CoV-2 variants with 100% accuracy

Genetic signatures may help predict immunotherapy response in patients with bladder cancer

'RNA fishing' technique identifies several proteins involved in the progression of melanoma

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

IRB Barcelona researchers discover genetic drivers of clonal hematopoiesis

Asexual reproduction results in more harmful genetic mutations than sexual reproduction

SLAS; Connecting the Life Sciences to Accelerate Research

Study shows cellular differences in brain development between modern humans and Neanderthals

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

NSF grant awarded to Zhang for producing muscle fiber with synthetic biology approach

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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