Genomics

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Disrupting a virus’s genome packaging can halt replication, study finds

Like savvy international travelers, viruses know exactly how to pack. With the genetic instructions for the next generation folded just so, snuggled into a custom-made outer covering studded with cell-grabbing proteins, these tiny invaders quest for new digs on the reg.

30 Aug 2022

Study reveals a 'stealing' mechanism that contributes to antibody diversity

A few years ago, Professor Kathrin de la Rosa and her colleagues in the lab of the Swiss immunologist Antonio Lanzavecchia made an unusual discovery.

29 Aug 2022

Single mutation in Kcnc3 gene causes learning deficits in mice

A single mutation in a gene, Kcnc3, which encodes a potassium channel in neurons, causes learning deficits in mice, UT Southwestern researchers report in a new study in PNAS.

29 Aug 2022

Researchers identify multiple genes and rare variants linked with Crohn's disease susceptibility

An international consortium of researchers has identified genetic variants in 10 genes that elevate a person's susceptibility to Crohn's disease, a form of inflammatory bowel disease.

29 Aug 2022

EPFL scientists uncover key mechanisms underlying the formation of protein tangles in the brain

Neurodegenerative disorders such as Alzheimer's and Parkinson's disease are associated with atypical proteins that form tangles in the brain, killing neurons.

29 Aug 2022

NRL fungal experiment to launch as part of NASA's scheduled Artemis I mission

An experiment prepared by the U.S. Naval Research Laboratory (NRL) will launch as part of NASA's scheduled Artemis I mission to orbit the moon Aug. 29.

26 Aug 2022

Cornell research offers insights into CRISPR RNA-guided Caspase system

New research from Cornell offers insights into a line of CRISPR systems, which could lead to promising antiviral and tissue engineering tools in animal and plants.

25 Aug 2022

Using the power of CRISPR to engineer better, stronger, longer-lived T cells

T cells used in immunotherapy treatments can get exhausted by the task of fighting cancer cells or get shutdown as they enter tumors.

24 Aug 2022

CRISPR genome-editing technology can be used as a tool to discover RNA therapeutics for lung cancer

An international team of scientists have demonstrated for the first time that CRISPR genome-editing technology can be used as a tool to find new gene therapies for lung cancer.

24 Aug 2022

Strong facial similarity in people is linked with shared genetic variants

A collection of photos of genetically unrelated lookalikes, along with DNA analysis, revealed that strong facial similarity is associated with shared genetic variants.

23 Aug 2022

UCI study uncovers key insights into 'parasitic genes'

They are considered "parasitic genes." Even though they comprise over half of human DNA, much remains to be learned about them.

23 Aug 2022

Researchers discover how the hearts of neonatal marsupials retain regenerative capacity

Wataru Kimura and colleagues at the RIKEN Center for Biosystems Dynamics Research in Japan have discovered how the hearts of newborn marsupials retain the ability to regenerate for several weeks.

23 Aug 2022

Super-resolution imaging reveals how disease causes cells to reorder their DNA incorrectly

Imagine you're trying to do a job and all of the information you need to do it is in a few books at the library.

22 Aug 2022

Researchers discover how patients with mutations in a DNA sequence develop pancreatic malformations

Researchers at the Centre for Genomic Regulation have identified a DNA sequence that is crucial for pancreatic differentiation and function – and for the first time – describe how it works.

22 Aug 2022

Scientists discover a mechanism used by insects in the development and regeneration of wings

The first mutation of the wingless gene was found by accident in Drosophila in the 1970s, following the observation of flies that did not possess wings, hence its name.

22 Aug 2022

Re-defining the limits of single batch assay stabilisation

In response to increasing demand for stabilised molecular diagnostic assays, we have significantly increased our single batch lyophilised reagent bead manufacturing throughput to 300,000 reactions per freeze drying run and are now progressing towards a capacity of 100 million tests per annum.

From Biofortuna Limited 22 Aug 2022

New resource can help researchers to assess how key genes control the differentiation of developing embryos

Years of work by developmental biologists from Trinity College Dublin, working with colleagues at the University of Edinburgh's MRC Human Genetics Unit, has yielded a resource of unparalleled detail that will help researchers assess how key genes control the differentiation of tissues and organs of developing embryos.

19 Aug 2022

Genomics

Disrupting a virus’s genome packaging can halt replication, study finds

Study reveals a 'stealing' mechanism that contributes to antibody diversity

Single mutation in Kcnc3 gene causes learning deficits in mice

Researchers identify multiple genes and rare variants linked with Crohn's disease susceptibility

EPFL scientists uncover key mechanisms underlying the formation of protein tangles in the brain

NRL fungal experiment to launch as part of NASA's scheduled Artemis I mission

Cornell research offers insights into CRISPR RNA-guided Caspase system

Using the power of CRISPR to engineer better, stronger, longer-lived T cells

CRISPR genome-editing technology can be used as a tool to discover RNA therapeutics for lung cancer

Strong facial similarity in people is linked with shared genetic variants

UCI study uncovers key insights into 'parasitic genes'

Researchers discover how the hearts of neonatal marsupials retain regenerative capacity

Super-resolution imaging reveals how disease causes cells to reorder their DNA incorrectly

Researchers discover how patients with mutations in a DNA sequence develop pancreatic malformations

Scientists discover a mechanism used by insects in the development and regeneration of wings

Re-defining the limits of single batch assay stabilisation

New resource can help researchers to assess how key genes control the differentiation of developing embryos

Researchers receive grant to develop purification membranes for large-scale manufacturing of viral vectors

Study reveals the unique and unconventional way mosquitoes process odors

Key gene sheds light on how people develop tolerance to pain-relievers over time

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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