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Scientists define key underlying process implicated in multiple sclerosis

Scientists at the Gladstone Institutes have defined for the first time a key underlying process implicated in multiple sclerosis (MS)-a disease that causes progressive and irreversible damage to nerve cells in the brain and spinal cord. This discovery offers new hope for the millions who suffer from this debilitating disease for which there is no cure.

30 Nov 2012

Tips to prevent holiday headaches

Holidays are a time for family, friends, and happy memories. But those joyful moments can be associated with stress – from marathon shopping, preparing for celebrations, and traveling. Stress and other stimuli may trigger or increase your headaches.

30 Nov 2012

Epizyme to present data from DOT1L and EZH2 inhibitor programs at 54th ASH annual meeting

Epizyme, Inc., a biopharmaceutical company leading the creation of personalized therapeutics to treat patients with genetically defined cancers, today announced the presentation of data evaluating the preclinical safety and efficacy of two of the Company's novel, potent and selective small molecule inhibitors. These inhibitors individually target DOT1L and EZH2, members of a class of epigenic enzymes called histone methyltransferases (HMTs).

30 Nov 2012

Modified vitamin D receptor may reduce risk of osteoporosis

Osteoporosis, or reduced bone mineral density that can increase the risk of fractures, may affect as many as 30% of women and 12% of men worldwide. One risk factor for osteoporosis is vitamin D deficiency.

30 Nov 2012

Exelixis announces FDA approval of COMETRIQ for treatment of medullary thyroid cancer

Exelixis, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved COMETRIQ (cabozantinib) for the treatment of progressive, metastatic medullary thyroid cancer (MTC).

30 Nov 2012

Varian's TrueBeam receives Indian AERB clearance for use in advanced radiosurgical treatments

Varian Medical Systems has received regulatory clearance from the Indian Atomic Energy Regulatory Board for the use of its unique TrueBeam High Intensity Mode for advanced radiosurgical treatments.

29 Nov 2012

European Medicines Agency accepts Exelixis’ COMETRIQ MAA for review

Exelixis, Inc. today announced the European Medicines Agency (EMA) has accepted for review the Marketing Authorization Application (MAA) for COMETRIQ (cabozantinib) for the proposed indication of treatment of progressive, unresectable, locally advanced, or metastatic medullary thyroid cancer (MTC).

29 Nov 2012

LP-211 compound shows promise against Fragile X syndrome

A potential new therapeutic strategy for treating Fragile X syndrome is detailed in a new report appearing in the current issue of Biological Psychiatry, from researchers led by Dr. Lucia Ciranna at University of Catania in Italy.

29 Nov 2012

AstraZeneca receives FDA approval for Cometriq to treat medullary thyroid cancer

The U.S. Food and Drug Administration today approved Cometriq (cabozantinib) to treat medullary thyroid cancer that has spread to other parts of the body (metastasized).

29 Nov 2012

InSite Vision completes enrollment in BromSite Phase 3 trial for reduction of pain, inflammation

InSite Vision Incorporated today announced that patient enrollment has been completed in the first Phase 3 clinical trial of BromSite (ISV-303) for the reduction of pain and inflammation after cataract surgery.

29 Nov 2012

Longer looks: Are 'pods' the solution to our long-term care crisis?; A Liver transplant in the nick of time; Pro-life activists and the abortion drop

In November 2006, when Clara Marshall began suffering from the effects of dementia, her family moved her into ... an assisted living home in Vancouver, Wash. ... just five months into her stay, Ms. Marshall, 81, was found dead in her room apparently strangled after getting her neck caught in side rails used to prevent her from rolling out of bed.

29 Nov 2012

Ponatinib thwarts T315I gene mutation in chronic myeloid leukemia

A previously invincible mutation in chronic myeloid leukemia (CML) has been thwarted by an investigational drug in a phase I clinical trial reported in the current edition of The New England Journal of Medicine.

29 Nov 2012

Study shows how PTPN22 variant linked with T1D influences susceptibility to autoimmunity

As part of their ongoing research on the role of genes in the development of type 1 diabetes, Joslin Diabetes Center scientists, in collaboration with scientists at the University of Würzburg, have demonstrated how a genetic variant associated with type 1 diabetes and other autoimmune diseases influences susceptibility to autoimmunity. The findings appear in the upcoming issue of Diabetes.

29 Nov 2012

Combination of blood test and whole-genome sequencing technology could screen cancers

Scientists at the Johns Hopkins Kimmel Cancer Center have combined the ability to detect cancer DNA in the blood with genome sequencing technology in a test that could be used to screen for cancers, monitor cancer patients for recurrence and find residual cancer left after surgery.

29 Nov 2012

DLKI-DIO3 miRNA cluster suppresses spread of cancer from its primary site

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the spread of cancer from its primary site.

29 Nov 2012

University of Cincinnati to lead Belatacept Early Steroid withdrawal Trial

The University of Cincinnati will lead a $5.2 million national trial studying removal of both corticosteroids and common immunosuppression treatments from the post-transplant drug regimen for kidney transplant patients.

29 Nov 2012

Yale and Mainz University Medical Center to extend collaboration

The University Medical Center at Johannes Gutenberg University Mainz, Germany and the renowned School of Medicine at Yale University, USA have agreed upon a future collaboration. This strategic partnership promises to provide an innovative stimulus for the Research Unit Translational Neurosciences at the Mainz University Medical Center. The resulting regular exchange will benefit both basic research and the training of young researchers.

29 Nov 2012

Mental health amongst top reasons why young people attend GPs in Mid West Ireland

A recent study of primary care support for youth mental health in the Mid West was undertaken by researchers at the Centre for Interventions in Infection, Inflammation & Immunity (4i), Graduate Entry Medical School, UL (www.4i.ie). The researchers surveyed physicians in Limerick, Clare, and North Tipperary and found mental health and family conflict represented the most frequent reasons why young people attended GPs.

29 Nov 2012

Combining statin treatment with better fitness improves survival in people with dyslipidaemia

Taking statins or being even modestly physically fit markedly improves survival in people with dyslipidaemia (abnormal levels of harmful blood fats/cholesterol), according to new research published Online First in The Lancet. But combining statin treatment with better fitness may do more to ward off death than either intervention alone.

29 Nov 2012

Blood test and gene sequencing combined to detect cancer

29 Nov 2012

Medical Condition News

Scientists define key underlying process implicated in multiple sclerosis

Tips to prevent holiday headaches

Epizyme to present data from DOT1L and EZH2 inhibitor programs at 54th ASH annual meeting

Modified vitamin D receptor may reduce risk of osteoporosis

Exelixis announces FDA approval of COMETRIQ for treatment of medullary thyroid cancer

Varian's TrueBeam receives Indian AERB clearance for use in advanced radiosurgical treatments

European Medicines Agency accepts Exelixis’ COMETRIQ MAA for review

LP-211 compound shows promise against Fragile X syndrome

AstraZeneca receives FDA approval for Cometriq to treat medullary thyroid cancer

InSite Vision completes enrollment in BromSite Phase 3 trial for reduction of pain, inflammation

Longer looks: Are 'pods' the solution to our long-term care crisis?; A Liver transplant in the nick of time; Pro-life activists and the abortion drop

Ponatinib thwarts T315I gene mutation in chronic myeloid leukemia

Study shows how PTPN22 variant linked with T1D influences susceptibility to autoimmunity

Combination of blood test and whole-genome sequencing technology could screen cancers

DLKI-DIO3 miRNA cluster suppresses spread of cancer from its primary site

University of Cincinnati to lead Belatacept Early Steroid withdrawal Trial

Yale and Mainz University Medical Center to extend collaboration

Mental health amongst top reasons why young people attend GPs in Mid West Ireland

Combining statin treatment with better fitness improves survival in people with dyslipidaemia

Blood test and gene sequencing combined to detect cancer

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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