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Trovagene, MD Anderson partner to detect transrenal BRAF mutations in metastatic cancers

Trovagene, Inc., a developer of transrenal molecular diagnostics, announced that it has entered into a clinical collaboration with The University of Texas MD Anderson Cancer Center to detect transrenal BRAF mutations in the urine of patients with advanced or metastatic cancers.

3 Jan 2013

A little extra fat could be protective

A review of almost 100 studies found that people who were overweight or slightly obese had a lower risk of dying compared to those considered "normal" weight.

3 Jan 2013

$Bayer, Onyx announce data from Nexavar Phase 3 trial on RAI-refractory differentiated thyroid cancer$

Bayer, Onyx announce data from Nexavar Phase 3 trial on RAI-refractory differentiated thyroid cancer

Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals, Inc. today announced that a Phase 3 trial of Nexavar (sorafenib) tablets in patients with locally advanced or metastatic radioactive iodine-refractory (RAI) differentiated thyroid cancer has met its primary endpoint of a statistically significant improvement of progression-free survival.

3 Jan 2013

18F-FDG PET/CT may become important distant staging modality in patients with breast cancer

New research published in the January issue of The Journal of Nuclear Medicine shows that 18F-fludeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) imaging offers significant prognostic stratification information at initial staging for patients with locally advanced breast cancer. When compared to conventional imaging, 18F-FDG PET/CT more accurately showed lesions in the chest, abdomen and bones in a single session, changing management for more than 50 percent of the patients in the study.

3 Jan 2013

Aerobic better than resistance training when it comes to weight and fat loss

A new study led by North Carolina researchers has found that when it comes to weight- and fat loss, aerobic training is better than resistance training. The study is believed to the largest randomized trial to directly compare changes in body composition induced by comparable amounts of time spent doing aerobic and resistant training, or both in combination, among previously inactive overweight or obese non-diabetic adults.

3 Jan 2013

Psychiatric patients at risk of hospitalization due to protected records

Medical centers that elect to keep psychiatric files private and separate from the rest of a person's medical record may be doing their patients a disservice, a Johns Hopkins study concludes.

3 Jan 2013

Gut bacterial communities play an integral role in protecting against human intestinal disorders

Instability in the composition of gut bacterial communities (dysbiosis) has been linked to common human intestinal disorders, including inflammatory bowel disease and colorectal cancer; however, it is unclear if dysbiosis can instigate disease or if it is a consequence of the underlying disorder.

3 Jan 2013

No significant difference in patient outcomes with RBC transfusions using lower threshold levels

The level at which red blood cells are transfused, a common treatment in clinical practice, is often deliberated among physicians. Guidelines for blood transfusion levels were only recently issued in March 2012 diminishing some of the debate. Today, in a new section called JAMA Clinical Evidence Synopsis, the Journal of the American Medical Association (JAMA), published a summary of the systematic review of the 19 clinical trials that compare higher versus lower hemoglobin thresholds in red blood cell transfusion.

3 Jan 2013

Improving research on BPA chemical may lead to better guidelines for human health

Following a three-year study using more than 2,800 mice, a University of Missouri researcher was not able to replicate a series of previous studies by another research group investigating the controversial chemical BPA. The MU study is not claiming that BPA is safe, but that the previous series of studies are not reproducible.

3 Jan 2013

Kareus announces start of KU-046 Phase I study in Alzheimer's

Kareus Therapeutics SA, the private biotechnology company focused on the development of novel therapeutics for the unmet treatment of age-related and chronic diseases, today announces the start of a Phase I clinical study following the Investigational New Drug (IND) approval from the US Food and Drug Administration for the development of KU-046, a first-in-class disease modifying new chemical entity discovered for the treatment of Alzheimer's disease using Kareus' proprietary bioenergetics and KARLECT platforms.

3 Jan 2013

Electroconvulsive therapy releases opiate-like substances

Researchers used electricity on certain regions in the brain of a patient with chronic, severe facial pain to release an opiate-like substance that's considered one of the body's most powerful painkillers.

3 Jan 2013

Deimination restores inner retinal visual function in murine demyelinating disease

Demyelinating diseases, such as multiple sclerosis (MS), are frequently associated with the progressive loss of vision. The retinal nerve damage is thought to be caused by immune system-mediated inflammation; however, other demyelinating disorders, such as Pelizaeus-Merzbacher disease, do not involve the immune system, suggesting that there are other causes of retinal nerve damage.

3 Jan 2013

Johns Hopkins scientists uncover itch-specific nerve cells in skin

Johns Hopkins researchers have uncovered strong evidence that mice have a specific set of nerve cells that signal itch but not pain, a finding that may settle a decades-long debate about these sensations, and, if confirmed in humans, help in developing treatments for chronic itch, including itch caused by life-saving medications.

3 Jan 2013

Prenatal brain development may be important influence on psychiatric risk later in life

Some brain changes that are found in adults with common gene variants linked to disorders such as Alzheimer's disease, schizophrenia, and autism can also be seen in the brain scans of newborns.

3 Jan 2013

UMDNJ-School of Osteopathic Medicine establishes Biomarker Discovery Center

Following recent discoveries by its researchers that could significantly change the diagnosis and treatment of a number of diseases, the University of Medicine and Dentistry of New Jersey (UMDNJ)-School of Osteopathic Medicine has established the Biomarker Discovery Center on its Stratford campus.

3 Jan 2013

Adrenomed creates Adrecizumab to decrease death rates from sepsis

The German corporation Adrenomed AG today announced its intentions to contribute to the reduction of mortality from sepsis and septic shock. Sepsis is an advanced systemic infection that travels via the blood stream to many of the body's vital organs, which can lead to death and disability.

3 Jan 2013

TFP5 molecule restores memory in mice with Alzheimer's

A new ray of hope has broken through the clouded outcomes associated with Alzheimer's disease. A new research report published in January 2013 print issue of the FASEB Journal by scientists from the National Institutes of Health shows that when a molecule called TFP5 is injected into mice with disease that is the equivalent of human Alzheimer's, symptoms are reversed and memory is restored-without obvious toxic side effects.

3 Jan 2013

Ineffective communication contributes to poor drug adherence

Even the best medicines in the world can be rendered ineffective if they are not taken as prescribed. The problem known as medication "non-adherence" is a major health issue in the United States, contributing to worse outcomes for people who have diabetes and other chronic diseases.

3 Jan 2013

Bisexual men more likely to conceal their sexual orientation

Bisexual men are less likely to disclose and more likely to conceal their sexual orientation than gay men. In the first study to look at the mental health of this population, researchers at Columbia University's Mailman School of Public Health found that greater concealment of homosexual behavior was associated with more symptoms of depression and anxiety.

3 Jan 2013

Heart attack patients may benefit from mild to moderate sleep-disordered breathing

People who suffer from breathing disorders such as sleep apnea are usually at higher risk for cardiovascular disease. But an intriguing new study from Technion-Israel Institute of Technology scientists suggests that some heart attack patients with these conditions may actually benefit from mild to moderate sleep-disordered breathing.

3 Jan 2013

Medical Condition News

Trovagene, MD Anderson partner to detect transrenal BRAF mutations in metastatic cancers

A little extra fat could be protective

Bayer, Onyx announce data from Nexavar Phase 3 trial on RAI-refractory differentiated thyroid cancer

18F-FDG PET/CT may become important distant staging modality in patients with breast cancer

Aerobic better than resistance training when it comes to weight and fat loss

Psychiatric patients at risk of hospitalization due to protected records

Gut bacterial communities play an integral role in protecting against human intestinal disorders

No significant difference in patient outcomes with RBC transfusions using lower threshold levels

Improving research on BPA chemical may lead to better guidelines for human health

Kareus announces start of KU-046 Phase I study in Alzheimer's

Electroconvulsive therapy releases opiate-like substances

Deimination restores inner retinal visual function in murine demyelinating disease

Johns Hopkins scientists uncover itch-specific nerve cells in skin

Prenatal brain development may be important influence on psychiatric risk later in life

UMDNJ-School of Osteopathic Medicine establishes Biomarker Discovery Center

Adrenomed creates Adrecizumab to decrease death rates from sepsis

TFP5 molecule restores memory in mice with Alzheimer's

Ineffective communication contributes to poor drug adherence

Bisexual men more likely to conceal their sexual orientation

Heart attack patients may benefit from mild to moderate sleep-disordered breathing

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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