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$ACE-inhibitors, angiotensin receptor blockers can treat heart failure with preserved ejection fraction$

ACE-inhibitors, angiotensin receptor blockers can treat heart failure with preserved ejection fraction

A novel study from Karolinska Institutet in Sweden suggests that commonly used drugs to treat heart failure and high blood pressure may have a wider range of application than earlier known, and also can be used against so called HFPEF - a type of heart failure that until now has been impossible to treat.

29 Nov 2012

NovImmune commences NI-0101 Phase I clinical trial in arthritis

NovImmune SA initiated dosing in a Phase I clinical trial of NI-0101, a monoclonal antibody drug candidate targeting toll-like receptor-4 (TLR4).

29 Nov 2012

Cancer-related fatigue and exercise: an interview with Dr Fiona Cramp

It is likely that there is more than one reason why people with cancer experience fatigue. The causes are likely to include side effects of the treatment that people are receiving for cancer as well as the direct effects of the cancer.

28 Nov 2012

Macular pigment screener launched by Elektron Technology

Elektron Technology is launching a new, easy-to-use macular pigment screener (MPS II) that can quickly identify those most at risk of developing age-related macular degeneration (AMD).

28 Nov 2012

Chalmers researcher develops world's first implantable robotic arm controlled by thoughts

The world's first implantable robotic arm controlled by thoughts is being developed by Chalmers researcher Max Ortiz Catalan. The first operations on patients will take place this winter.

28 Nov 2012

Combination of mixed amphetamine salts and topiramate shows promise for cocaine dependence

Medication development efforts for cocaine dependence have yet to result in an FDA approved treatment. The powerful rewarding effects of cocaine, the profound disruptive impact of cocaine dependence on one's lifestyle, and the tendency of cocaine to attract people who make poor life choices and then exacerbate impulsive behavior all make cocaine a vexing clinical condition.

28 Nov 2012

Trovagene develops first molecular diagnostic test to detect KRAS mutations from urine samples

Trovagene, Inc. today announced successful development of its first molecular diagnostic test capable of detecting KRAS mutations from a urine specimen. Transfer of the transrenal KRAS test to the company's CLIA lab is expected to be completed in December 2012 with commercial availability expected in January 2013.

28 Nov 2012

Warfarin treatment after aortic valve replacement reduces risk of cardiovascular death

Although current guidelines recommend 3 months of anticoagulation treatment after bioprosthetic aortic valve replacement surgery, a study that included more than 4,000 patients found that patients who had warfarin therapy continued between 3 and 6 months after surgery had a lower rate of cardiovascular death, according to a study in the November 28 issue of JAMA.

28 Nov 2012

Engineered ICCs can improve pancreatic islet transplantation and cure diabetes mellitus

A study published in the current issue of Cell Transplantation, now freely available on-line, reports that a team of researchers in South Korea have successfully engineered islet cell clusters (ICCs) that will improve pancreatic islet transplantation and offer promise for curing diabetes mellitus.

28 Nov 2012

Injecting Wnt7a protein could prevent Duchenne muscular dystrophy

Scientists have discovered that injecting a novel human protein into muscle affected by Duchenne muscular dystrophy significantly increases its size and strength, findings that could lead to a therapy akin to the use of insulin by diabetics.

28 Nov 2012

Hebrew University of Jerusalem develops sonar vision device for congenitally blind people

A "sonar vision" system that enables people who are blind from birth to perceive the shape of a face, a house or even words and letters, is being developed by a team at the Hebrew University of Jerusalem.

28 Nov 2012

Link between high fructose corn syrup intake and diabetes prevalence

A new study by University of Southern California (USC) and University of Oxford researchers indicates that large amounts of high fructose corn syrup (HFCS) found in national food supplies across the world may be one explanation for the rising global epidemic of type 2 diabetes and resulting higher health care costs.

28 Nov 2012

French National Center for Scientific Research scientist wins American Epilepsy Society award

Richard Miles, Ph.D., Research Director, French National Center for Scientific Research, and Group Leader, Cortex and Epilepsy, Institute for the Brain and Spinal Cord, Centre Hospitalier Universtaire Pitie-Salpetriere, Paris, has been named recipient of the prestigious 2012 Epilepsy Research Recognition Award for Basic Science conferred by the American Epilepsy Society (AES).

28 Nov 2012

Researchers discover alternative mechanism for Ras protein activation

The protein Ras plays an important role in cellular growth control. Researchers have focused on the protein because mutations in its gene are found in more than 30 percent of all cancers, making it the most prevalent human oncogene.

28 Nov 2012

Bayer completes recruitment of first cohort for BAY 86-6150 Phase II/III study in hemophilia

Bayer's BAY 86-6150 is being investigated in a Phase II/III study called TRUST (TReatment with Unique recombinant rFVIIa STudy), and the recruitment of the first cohort is now complete.

28 Nov 2012

Yoga appears to be effective treatment for neck pain

According to published estimates, some 20 percent of the population suffers from chronic neck pain caused by a variety of structural dysfunctions in the neck, resulting in impaired quality of life and lost work time. A German study published in The Journal of Pain showed that yoga appears to be an effective treatment for neck pain and provides added benefits of improved psychological well being and quality of life.

28 Nov 2012

Florbetapir PET scans can detect brain amyloid deposits associated with Alzheimer’s

A test to detect brain amyloid deposits associated with Alzheimer disease (AD) provides doctors with useful information on treatment and further testing for patients with cognitive impairment, according to a study published online by the journal Alzheimer Disease & Associated Disorders.

28 Nov 2012

Prevalence of mental health diagnoses increases with long duration of opioid use

Most patients taking opioids for low back pain or other pain syndromes are prescribed low-to moderate doses, but a substantial number are given higher doses. Although there is no consensus on an absolute limit because tolerance varies over time among individual patients, what is known, however, is higher does are associated with elevated risks for side effects, addiction, overdoses and death.

28 Nov 2012

Off label atypical antipsychotic use lacks safety and effectiveness in patients over 40

In older adults, antipsychotic drugs are commonly prescribed off-label for a number of disorders outside of their Food and Drug Administration (FDA)-approved indications - schizophrenia and bipolar disorder. The largest number of antipsychotic prescriptions in older adults is for behavioral disturbances associated with dementia, some of which carry FDA warnings on prescription information for these drugs.

28 Nov 2012

The Neuro clinician-scientists to further research on HIV/AIDS, Parkinson's

Clinician-scientists take a unique, integrated approach that is essential to advancing science and medicine. Problems encountered in the clinic inspire research and new findings from the labs are directly applied to patients' needs.

28 Nov 2012

Medical Condition News

ACE-inhibitors, angiotensin receptor blockers can treat heart failure with preserved ejection fraction

NovImmune commences NI-0101 Phase I clinical trial in arthritis

Cancer-related fatigue and exercise: an interview with Dr Fiona Cramp

Macular pigment screener launched by Elektron Technology

Chalmers researcher develops world's first implantable robotic arm controlled by thoughts

Combination of mixed amphetamine salts and topiramate shows promise for cocaine dependence

Trovagene develops first molecular diagnostic test to detect KRAS mutations from urine samples

Warfarin treatment after aortic valve replacement reduces risk of cardiovascular death

Engineered ICCs can improve pancreatic islet transplantation and cure diabetes mellitus

Injecting Wnt7a protein could prevent Duchenne muscular dystrophy

Hebrew University of Jerusalem develops sonar vision device for congenitally blind people

Link between high fructose corn syrup intake and diabetes prevalence

French National Center for Scientific Research scientist wins American Epilepsy Society award

Researchers discover alternative mechanism for Ras protein activation

Bayer completes recruitment of first cohort for BAY 86-6150 Phase II/III study in hemophilia

Yoga appears to be effective treatment for neck pain

Florbetapir PET scans can detect brain amyloid deposits associated with Alzheimer’s

Prevalence of mental health diagnoses increases with long duration of opioid use

Off label atypical antipsychotic use lacks safety and effectiveness in patients over 40

The Neuro clinician-scientists to further research on HIV/AIDS, Parkinson's

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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