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Lipid Therapeutics to proceed with US LT-02 Phase III trial for mild-moderate ulcerative colitis

Lipid Therapeutics announces today that it has successfully filed its first US IND for its lead product LT-02 and is now in a position to proceed with a planned Phase III trial in the US in mild-moderate ulcerative colitis patients. The LT-02 IND was subject to the FDA's customary 30 day review period.

11 Apr 2013

CPAP treatment increases work productivity for people with sleep apnoea

Continuous positive airway pressure is effective at increasing work productivity, according to a new study.

11 Apr 2013

Omeros' GPCR platform unlocks new drug targets against multiple sclerosis

Omeros Corporation today announced positive data in the most commonly used model for studying the clinical and pathological features of multiple sclerosis (MS), further advancing its development program of GPR17-targeting compounds for the treatment of MS. Compounds previously discovered by Omeros that inhibit GPR17, an orphan G protein-coupled receptor (GPCR) unlocked by Omeros, significantly improved function from experimental autoimmune encephalomyelitis (EAE) in mice.

11 Apr 2013

Modulation of cerebral endocannabinoid system may help treat Fragile X chromosome syndrome

Researchers at the University of the Basque Country (UPV/EHU) and the Achucarro neurosciences centre have discovered a new therapy for the fragile X chromosome syndrome. This new therapy proposes the modulation of the cerebral endocannabinoid system in order to ameliorate the symptoms of the disease.

11 Apr 2013

Abbott's ARCHITECT Galectin-3 assay earns CE mark

Abbott today announced CE Marking (Conformite Europeenne) for the ARCHITECT Galectin-3 assay, a test to aid doctors in assessing the prognosis of patients diagnosed with chronic heart failure.

11 Apr 2013

Further research needed into therapeutic potential of rTMS for focal hand dystonia

Repetitive transcranial magnetic stimulation (rTMS) is being increasingly explored as a therapeutic tool for movement disorders associated with deficient inhibition throughout the central nervous system. This includes treatment of focal hand dystonia (FHD), characterized by involuntary movement of the fingers either curling into the palm or extending outward.

11 Apr 2013

Gold nano-bullets to defeat cancer

Cutting edge research into an experimental therapy that deploys nano-particles of gold in the fight against cancer earned an Alberta high school student, 16, top national honours today in the 2013 "Sanofi BioGENEius Challenge Canada" (SBCC).

11 Apr 2013

Decisions people make after being diagnosed with major health issue may lead to higher health risks

It may seem counter-intuitive to take health advice from a marketing professor, but when it comes to analyzing consumer data and its relationship to managing health issues such as diabetes, one University of Alberta researcher may have the right prescription.

11 Apr 2013

OncoMed highlights progress of anti-cancer biologics at AACR annual meeting

OncoMed Pharmaceuticals, Inc., a clinical-stage company developing novel therapeutics that target cancer stem cells (CSCs), or tumor-initiating cells, today summarized new data highlighting the progress of OncoMed's pipeline of anti-cancer biologics presented this week in an oral presentation and five posters at the Annual Meeting of the American Association of Cancer Research in Washington, DC.

11 Apr 2013

Conference on Malignant Hyperthermia to be held in Orlando

Learn the basics on how recognize, diagnose, and treat Malignant Hyperthermia by attending at the "MH Let's Save a Life" conference where patients sit side by side with healthcare professionals, students, and families learning about MH from experts affiliated with MHAUS on June 8, 2013 from 10 am - 4 pm at Orlando Regional Medical Center located in Orlando, FL.

11 Apr 2013

$Pharmacyclics presents positive results of ibrutinib Phase II trial in untreated, relapsed and refractory CLL patients$

Pharmacyclics presents positive results of ibrutinib Phase II trial in untreated, relapsed and refractory CLL patients

Pharmacyclics, Inc. today announced results from a Phase II trial of the investigational oral agent ibrutinib which demonstrated rapid and sustained disease control as a monotherapy in untreated, relapsed and refractory chronic lymphocytic leukemia (CLL) patients, irrespective of characteristics that predict poor outcomes to chemoimmunotherapy.

11 Apr 2013

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Scientists at The Scripps Research Institute have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the Alzheimer's process and how to prevent it.

11 Apr 2013

Cellectis CanCELL cell lines enable drug positioning in cancer pathways

CanCELL cell lines are featuring gene knock-outs of the major cancer relevant oncogenes and tumor suppressor genes. This new product line answers identified market needs in oncology research and drug discovery.

11 Apr 2013

German researchers evaluate short-term cognitive pain management techniques for acute pain

Those who accept their pain condition are best able to tolerate pain, while distraction can be the way to lower pain intensity, according to research reported in The Journal of Pain, the peer review publication of the American Pain Society.

11 Apr 2013

Study reports role of cytochrome c oxidase as prognostic marker in GBM patients' tumor tissues

Researchers may have discovered a more accurate way to predict how long patients with the deadliest form of brain cancer will live, according to an analysis by researchers from the University of Alabama at Birmingham published today in the journal PLOS ONE.

11 Apr 2013

New data on use of PBD dimers as warheads in ADCs presented at AACR annual meeting

Spirogen, a leading oncology-focused company developing DNA sequence targeted agents, and BioAtla LLC, a San Diego headquartered antibody therapeutics developer, today announced new data on the use of pyrrolobenzodiazepine (PBD) dimers as warheads in antibody drug conjugates (ADCs) at the annual meeting of the American Association for Cancer Research (AACR) in Washington, DC.

11 Apr 2013

SAGIC researchers aim to compile genetic, genomic and phenotypic data of sleep apnea patients

As more and more data indicate that sleep apnea is linked with cardiovascular disease, stroke, diabetes and even an increase in deaths related to car accidents, an international consortium spanning five continents is working together to unravel the genetic basis for the condition.

11 Apr 2013

Study reveals new method to restore grip function in people with tetraplegia

A new method in which a number of operations are performed simultaneously can provide people with tetraplegia with a better grip function and the ability to open their hand. This method also shortens the patient's rehabilitation period by at least three months, reveals a doctoral thesis from the Sahlgrenska Academy, University of Gothenburg, Sweden.

11 Apr 2013

Computational simulations can help understand, treat cardiac rhythm disorders

Computational models of the human heart can be very useful in studying not just the basic mechanisms of heart function, but also to analyze the heart in a diseased state, and come up with methods for diagnosis and therapy.

11 Apr 2013

Exposure to metabolic risks of cardiovascular disease increasing

Despite their greater life expectancy, the adults of today are less "metabolically" healthy than their counterparts of previous generations.

11 Apr 2013

Medical Condition News

Lipid Therapeutics to proceed with US LT-02 Phase III trial for mild-moderate ulcerative colitis

CPAP treatment increases work productivity for people with sleep apnoea

Omeros' GPCR platform unlocks new drug targets against multiple sclerosis

Modulation of cerebral endocannabinoid system may help treat Fragile X chromosome syndrome

Abbott's ARCHITECT Galectin-3 assay earns CE mark

Further research needed into therapeutic potential of rTMS for focal hand dystonia

Gold nano-bullets to defeat cancer

Decisions people make after being diagnosed with major health issue may lead to higher health risks

OncoMed highlights progress of anti-cancer biologics at AACR annual meeting

Conference on Malignant Hyperthermia to be held in Orlando

Pharmacyclics presents positive results of ibrutinib Phase II trial in untreated, relapsed and refractory CLL patients

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Cellectis CanCELL cell lines enable drug positioning in cancer pathways

German researchers evaluate short-term cognitive pain management techniques for acute pain

Study reports role of cytochrome c oxidase as prognostic marker in GBM patients' tumor tissues

New data on use of PBD dimers as warheads in ADCs presented at AACR annual meeting

SAGIC researchers aim to compile genetic, genomic and phenotypic data of sleep apnea patients

Study reveals new method to restore grip function in people with tetraplegia

Computational simulations can help understand, treat cardiac rhythm disorders

Exposure to metabolic risks of cardiovascular disease increasing

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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