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Automated prediction of Alzheimer's disease progression using speech and machine learning

Trying to figure out whether someone has Alzheimer's disease usually involves a battery of assessments - interviews, brain imaging, blood and cerebrospinal fluid tests.

25 Jun 2024

Genetic variation in people of African ancestry linked to increased risk of diabetes complications

A genetic variation common in people of African ancestry is associated with an increased risk of complications from diabetes, including diabetic retinopathy, according to a report published June 25 in the journal Nature Medicine.

25 Jun 2024

Nitrate from plant sources linked to lower risk of mortality

New research from Edith Cowan University (ECU) has found that nitrate from plant sources is associated with a lower risk of mortality while nitrate from other sources such as animal-based foods, processed meat and tap water, is linked to a higher risk of mortality.

25 Jun 2024

Wearable devices show how sleep patterns change with health conditions

Examine changes in the sleep phenotype of an individual over time and to determine if these changes in sleep patterns or phenotypes are informative about periods of acute illness.

25 Jun 2024

Research shows gut bacteria's role in mental resilience and reduced anxiety

Researchers characterized brain-gut microbiome (BGM) patterns related to stress resilience.

25 Jun 2024

Open-source platform enables high-definition spatial transcriptomics

An open-source platform developed by researchers in Nikolaus Rajewsky's lab at the Max Delbrück Center creates molecular maps from patient tissue samples with subcellular precision, enabling detailed study and potentially enhancing routine clinical pathology. The study was published in "Cell."

25 Jun 2024

Beyond genes, new research explores mechanics and calcium signaling

Using animals to study heart disease doesn't always translate well to human health outcomes, and human heart cells available for research don't work outside the human body.

25 Jun 2024

Multi-regional sampling uncovers hidden complexity in liver cancer

A study led by clinician-scientists and scientists from the National Cancer Centre Singapore (NCCS) and A*STAR's Genome Institute of Singapore (GIS) and funded by the National Research Foundation Singapore (NRF) has discovered unexpected molecular heterogeneity even within the same liver tumors. More than 40% of HCC harbors more than one molecular subtype within the same tumor and in these, the clinical outcomes for the patients are best predicted by the most aggressive subtype.

25 Jun 2024

RENEW system utilizes machine learning for rare disease diagnosis

At Mayo Clinic, the mission to solve the unsolvable is at the heart of every rare disease case. Each diagnosis is a testament to perseverance, innovation and the relentless pursuit of answers.

25 Jun 2024

New enzyme targets hold promise for cancer therapies

Researchers at Baylor College of Medicine and collaborating institutions have uncovered new potential therapeutic targets for cancer and new insights into existing cancer drug targets, expanding the breadth of possibilities for treating this disease. Using a comprehensive approach that included integrating proteomics, genomics and epigenomics data from 10 cancer types, the team identified protein and small protein or peptide targets in cancer tissues and validated many of them experimentally as promising candidates for therapeutic strategies. The study appeared in Cell.

25 Jun 2024

Teleneurology offers solution to neurologist shortage

One of the first studies to examine patient acceptability of teleneurology and determine factors influencing acceptability across neurological conditions, has found teleneurology was highly acceptable across the full range of patients with different neurological diagnoses, including headache, movement disorders and other neurological symptoms and diagnoses. The study also determined that the more medical complexity -- having additional diseases -- was associated with increased patient satisfaction with teleneurology.

25 Jun 2024

Global food collapse looms amid heat and water stress, warns new study

By 2050, global food production could decline by up to 14% due to heat and water stress, leading to 1.36 billion more people experiencing severe food insecurity, highlighting the urgent need for climate change mitigation.

25 Jun 2024

UCL research reveals anxiety as a major risk factor for Parkinson's

The risk of developing Parkinson's is at least twice as high in people with anxiety compared to those without, finds a new study by UCL researchers.

24 Jun 2024

WEHI study reveals new methods in detecting necroptosis

Fully automated diagnostic techniques, including liquid handling robots, are poised to improve the lives of millions of people living with inflammatory diseases worldwide.

24 Jun 2024

Chronic loneliness linked to increased stroke risk in older adults

Chronic loneliness may significantly raise older adults' risk of stroke, according to a new study led by Harvard T.H. Chan School of Public Health.

24 Jun 2024

Enhancing adoptive T-cell therapy with nanowire innovation

Adoptive T-cell therapy has revolutionized medicine. A patient's T-cells - a type of white blood cell that is part of the body's immune system - are extracted and modified in a lab and then infused back into the body, to seek and destroy infection, or cancer cells.

24 Jun 2024

Study reveals cannabis and tobacco users face higher COVID-19 hospitalization and adverse outcomes

Researchers found that cannabis and tobacco use significantly increase the risk of hospitalization and adverse outcomes in COVID-19 patients, even when controlling for other factors.

24 Jun 2024

New study in rhesus macaques offers early intervention window for Alzheimer's

Research in nonhuman primates is opening the possibility of testing treatments for the early stages of Alzheimer's and similar diseases, before extensive brain cell death and dementia set in.

24 Jun 2024

Study reveals high rates of aspirin use for CVD prevention among older adults

A survey representing about 150 million adults annually suggests that aspirin use for primary prevention of cardiovascular disease (CVD) remains prevalent among older adults, contrary to recommendations from the American College of Cardiology and the American Heart Association.

24 Jun 2024

New ketamine slow-release tablet shows promise in treating severe depression

A new tablet form of ketamine has shown promise in treating severe depression, offering a potential alternative to existing clinic-based treatments that can be expensive and lacking in convenience for some patients.

24 Jun 2024