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Impact of CLK kinase inhibitors 1C8 and GPS167 on cancer cell proliferation and metastasis

A new research paper was published in Oncotarget's Volume 15 on May 16, 2024, entitled, "The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response."

20 May 2024

Donepezil fails to enhance cognitive abilities in breast cancer survivors: Phase III trial results

Many breast cancer survivors report cancer-related cognitive impairment following chemotherapy, although prevalence rates and severity vary.

20 May 2024

New CRISPR screen method reveals cellular drivers of neurological disorders

The brain is often referred to as a "black box" - one that's difficult to peer inside and determine what's happening at any given moment.

20 May 2024

Updated medical guidance reject 'excited delirium' to prevent misuse in police custody cases

Updated medical guidance on excited delirium, the controversial term accused of covering up deaths in police custody, including that of George Floyd, is being brought forward before its scheduled date of October 2025, reports The BMJ today.

20 May 2024

Taurine supplementation shows promise in reducing metabolic syndrome risk factors, study finds

A study in Nutrition & Diabetes meta-analyzed randomized clinical trials and found that taurine supplementation significantly reduces key risk factors for metabolic syndrome, such as high blood pressure, fasting blood glucose, and triglycerides, with no notable adverse effects.

20 May 2024

Study uncovers key biological pathways driving psoriasis inflammation

A certain biological pathway, a set of linked reactions in the body, drives the inflammation seen in the skin disease psoriasis, a new study finds.

20 May 2024

Low-fat diets significantly reduce lung cancer risk in older adults, study finds

Study found that adhering to low-fat diets significantly reduces lung cancer risk in older adults, with the most substantial benefits observed in current smokers. High consumption of saturated fats was linked to increased lung cancer risk, particularly for small-cell lung cancer.

20 May 2024

Ketogenic diets linked to cellular aging in vital organs, new study finds

Study reveals that ketogenic diets induce cellular senescence in mice, affecting organs like the kidneys and heart through AMPK and p53 pathways. These findings highlight potential long-term risks associated with ketogenic diets.

20 May 2024

Dupilumab shows promising results in Phase 3 trial for COPD with type 2 inflammation

Chronic obstructive pulmonary disease patients with type 2 inflammation may soon gain access to a new drug - dupilumab - that showed rapid and sustained improvements in patients in a pivotal Phase 3 clinical trial, researchers report in the New England Journal of Medicine.

20 May 2024

Researchers design new regenerative medicine therapy to accelerate diabetic wound repair

Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair.

20 May 2024

Early blood pressure control in ambulances shows no clear benefit for stroke patients, study finds

Study published in the New England Journal of Medicine evaluated the impact of early blood-pressure control in ambulances for acute stroke patients, finding no significant improvement in clinical outcomes compared to standard care.

20 May 2024

Study reveals increased risk of lung cancer in e-cigarette users after smoking cessation

Former cigarette smokers who use e-cigarettes or vaping devices may be at higher risk for lung cancer than those who don't vape, according to research published at the ATS 2024 International Conference.

20 May 2024

Transportation of cancer nanomedicines into solid tumors

A new study conducted by the Wilhelm Lab at the University of Oklahoma examines a promising development in biomedical nanoengineering.

20 May 2024

From research to practice: Closing the divide in obesity management

As research continues to produce evidence about the underlying causes of obesity and optimal strategies to treat and manage obesity have evolved, there are disparities in application of the latest scientific advances in the clinical care that people with obesity receive.

20 May 2024

Study identifies PI3K-beta as key target in overcoming chemotherapy resistance in glioblastoma

For many patients with a deadly type of brain cancer called glioblastoma, chemotherapy resistance is a big problem.

20 May 2024

Enhanced tumor treatment using antibody-loaded extracellular vesicles

Researchers at Karolinska Institutet in Sweden have succeeded in delivering targeted cancer treatment via small membrane bubbles that our cells use to communicate.

20 May 2024

Inherited iron defects uncovered in endemic Indian population

Although iron deficiency anemia is the most prevalent form of anemia globally, it may be underdiagnosed due to lack of awareness or methodical screening.

20 May 2024

New mechanism discovered for Chagas disease-induced heart damage

Jyothi Nagajyothi, Ph.D. and her laboratory at the Hackensack Meridian Center for Discovery and Innovation (CDI) have identified what may be the main mechanism for how chronic Chagas Disease, a parasitic infection affecting millions of people worldwide, can cause irreversible and potentially fatal heart damage.

20 May 2024

Disabling survival pathways could be a promising strategy for brain tumor treatment

When you disable the brakes on a race car, it quickly crashes. Dr. Barak Rotblat wants to do something similar to brain cancer cells.

20 May 2024

Internet-based CBT effectively reduces depression and insomnia, study shows

A new study at Hebrew University examined the effects of guided internet-based cognitive behavioral therapy for depression, focusing on the therapeutic alliance and attachment styles.

20 May 2024

Medical Condition News

Impact of CLK kinase inhibitors 1C8 and GPS167 on cancer cell proliferation and metastasis

Donepezil fails to enhance cognitive abilities in breast cancer survivors: Phase III trial results

New CRISPR screen method reveals cellular drivers of neurological disorders

Updated medical guidance reject 'excited delirium' to prevent misuse in police custody cases

Taurine supplementation shows promise in reducing metabolic syndrome risk factors, study finds

Study uncovers key biological pathways driving psoriasis inflammation

Low-fat diets significantly reduce lung cancer risk in older adults, study finds

Ketogenic diets linked to cellular aging in vital organs, new study finds

Dupilumab shows promising results in Phase 3 trial for COPD with type 2 inflammation

Researchers design new regenerative medicine therapy to accelerate diabetic wound repair

Early blood pressure control in ambulances shows no clear benefit for stroke patients, study finds

Study reveals increased risk of lung cancer in e-cigarette users after smoking cessation

Transportation of cancer nanomedicines into solid tumors

From research to practice: Closing the divide in obesity management

Study identifies PI3K-beta as key target in overcoming chemotherapy resistance in glioblastoma

Enhanced tumor treatment using antibody-loaded extracellular vesicles

Inherited iron defects uncovered in endemic Indian population

New mechanism discovered for Chagas disease-induced heart damage

Disabling survival pathways could be a promising strategy for brain tumor treatment

Internet-based CBT effectively reduces depression and insomnia, study shows

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