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Modulating PN aggregase pathway may offer hope for Alzheimer’s disease

Proteostasis Therapeutics announced today that modulating a key Proteostasis Network (PN) pathway may offer a novel approach to Alzheimer’s disease, a finding that was published in the journal Cell by its scientific founders Andrew Dillin, Ph.D., and Jeffery Kelly, Ph.D. The publication describes how regulation of an aggregase pathway reduced the neurodegenerative effects of beta amyloid aggregates that are a hallmark of the disease.

16 Dec 2009

VA and Department of Defense clinical practice guidelines for mTBI

The current issue of the Department of Veterans Affairs (VA's) Journal of Rehabilitation Research and Development (JRRD) features 19 timely scientific articles on traumatic brain injury (TBI), based on work by VA researchers and colleagues from a variety of disciplines. The papers were commissioned for a "state of the art" conference VA held last year to advance research in this area.

16 Dec 2009

EDP Biotech develops a simple blood test for detecting early-stage colon cancer

Medical researchers with EDP Biotech Corporation (EDP) have captured national attention with their revolutionary new technology for a simple blood test to detect early-stage colon cancer.

16 Dec 2009

Englerin A possesses high toxicity for kidney cancer cells, researchers discover

Englerin A, a natural product recently discovered in an African plant, possesses high toxicity for kidney cancer cells but low toxicity for other cells. Therefore this compound is potentially qualified for further evaluation toward an application in cancer therapy.

16 Dec 2009

ThromboGenics completes enrollment in second microplasmin Phase III trial

ThromboGenics NV, a biopharmaceutical company focused on the discovery and development of innovative treatments for eye disease, vascular disease and cancer, announces today that it has completed the enrolment of the second Phase III trial evaluating microplasmin for the non-surgical treatment of eye disease.

16 Dec 2009

Celebrities unveil Race for Life 2010 t-shirts to raise money for Cancer Research UK

A TRIO of celebrities including choreographer, Arlene Phillips; girlfriend of Arsenal star Theo Walcott, Melanie Slade; and fashion designer Tracey Boyd, have given the classic white tee a fun twist with a splash of colour as their new collection of Race for Life 2010 t-shirts is unveiled to raise money for Cancer Research UK.

16 Dec 2009

Preclinical study of Arno Therapeutics' drug candidate AR-42 presented at ASH 2009

Arno Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on oncology therapeutics, today announced the presentation of a poster at the annual American Society of Hematology (ASH) meeting that describes the preclinical activity of Arno’s drug candidate AR-42 against leukemia stem cells (LSCs).

16 Dec 2009

NEI study reports 66.4 percent increase in myopia in Americans

According to the American Academy of Ophthalmology, the 66.4 percent increase in myopia in Americans since the 1970s, as reported in the recent National Eye Institute (NEI) study, is significant and will impact healthcare costs as well as vision quality.

16 Dec 2009

Physicians need to utilize best practices to treat HAE patients in emergency settings

Hereditary Angioedema (HAE) is an autosomal dominant disease causing acute attacks of intense edema. These attacks can result in life-threatening complications, including asphyxiation.

16 Dec 2009

Nitric oxide opens up new treatment option for septic shock

Scientists at VIB and Ghent University in Flanders, Belgium have found an unexpected ally for the treatment of septic shock, the major cause of death in intensive care units.

16 Dec 2009

New top-line results for patient preference study evaluating Kristalose for Oral Solution announced

Cumberland Pharmaceuticals Inc. (CPIX) today announced new top-line results for a patient preference study evaluating Kristalose (lactulose) for Oral Solution, a prescription laxative packaged as a crystalline powder, compared to similar products in liquid forms.

16 Dec 2009

Higher leptin levels associated with lower incidence of AD and dementia

Persons with higher levels of leptin, a protein hormone produced by fat cells and involved in the regulation of appetite, may have an associated reduced incidence of Alzheimer disease and dementia, according to a study in the December 16 issue of JAMA.

16 Dec 2009

Study suggests physical activity influences depression and fatigue by increasing self-efficacy

Physical activity is known to reduce depression and fatigue in people struggling with chronic illness. A new study indicates that this effect stems from an individual's sense of mastery over - or belief in his or her ability to achieve - certain physical goals.

16 Dec 2009

Discovery may yield new treatments for hormone-resistant prostate cancer

Patients with advanced prostate cancer are often treated with hormones, but when the tumours start growing again they have more and different blood vessels, reveals a thesis from the Sahlgrenska Academy, at the University of Gothenburg, Sweden. This discovery paves the way for new treatments for hormone-resistant prostate cancer.

16 Dec 2009

University of Florida obtains stimulus grant to establish ataxia consortium

University of Florida neurologists are trying to change that with the help of a $1 million Challenge grant from the National Institute of Neurological Disorders and Stroke to establish a nationwide network of physician-scientists with expertise in clinical ataxia research.

16 Dec 2009

UCLA researchers find link between brain cancer and fatty acid synthesis

Inhibiting fatty acid synthesis in brain cancer cells may offer a new option to treat about 50 percent of deadly glioblastomas that are driven by amplified signaling of the epidermal growth factor receptor (EGFR), according to a first-of-its-kind study by researchers at UCLA's Jonsson Comprehensive Cancer Center.

16 Dec 2009

Repligen receives $731,000 to support ongoing development of new treatments for Friedreich's ataxia

Repligen Corporation today announced that the Company has received $731,000 in research funding to support the ongoing development of new treatments for Friedreich's ataxia from the Muscular Dystrophy Association (MDA).

16 Dec 2009

Binghamton University psychologist to provide new weapons to fight against childhood depression

Research by Binghamton University psychologist Brandon Gibb could provide new weapons for the fight against childhood depression. Working with colleagues around the country, he hopes to identify the causes of mental-health problems in kids and define trajectories of risk for depression.

16 Dec 2009

Nutrition education may help diabetes patients to adopt better dietary habits

Nine weeks of education about the glycemic index in foods is enough to encourage adults with type 2 diabetes to adopt better dietary habits that result in improvements to their health, recent research suggests.

16 Dec 2009

Low plasma CETP activity associated with increased risk of heart disease, says study

Although seen as a potential heart disease therapy, raising high-density lipoprotein (HDL) cholesterol levels by inhibiting activity of a transfer protein may not be effective, a new study suggests.

16 Dec 2009

Medical Condition News

Modulating PN aggregase pathway may offer hope for Alzheimer’s disease

VA and Department of Defense clinical practice guidelines for mTBI

EDP Biotech develops a simple blood test for detecting early-stage colon cancer

Englerin A possesses high toxicity for kidney cancer cells, researchers discover

ThromboGenics completes enrollment in second microplasmin Phase III trial

Celebrities unveil Race for Life 2010 t-shirts to raise money for Cancer Research UK

Preclinical study of Arno Therapeutics' drug candidate AR-42 presented at ASH 2009

NEI study reports 66.4 percent increase in myopia in Americans

Physicians need to utilize best practices to treat HAE patients in emergency settings

Nitric oxide opens up new treatment option for septic shock

New top-line results for patient preference study evaluating Kristalose for Oral Solution announced

Higher leptin levels associated with lower incidence of AD and dementia

Study suggests physical activity influences depression and fatigue by increasing self-efficacy

Discovery may yield new treatments for hormone-resistant prostate cancer

University of Florida obtains stimulus grant to establish ataxia consortium

UCLA researchers find link between brain cancer and fatty acid synthesis

Repligen receives $731,000 to support ongoing development of new treatments for Friedreich's ataxia

Binghamton University psychologist to provide new weapons to fight against childhood depression

Nutrition education may help diabetes patients to adopt better dietary habits

Low plasma CETP activity associated with increased risk of heart disease, says study

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