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Key molecular switch linked to HD identified

Scientists have identified a key molecular switch that may drive the onset of Huntington's disease (HD), an incurable neurodegenerative disorder that leads to severe disruptions in muscle coordination and cognitive function. The research, published by Cell Press in the December 24 issue of the journal Neuron, enhances the understanding of HD pathogenesis and may direct new strategies for treating this devastating brain disease.

24 Dec 2009

Potential new therapeutic option for prevention of PD-associated neuropathology

Scientists have identified a synergistic interaction that disrupts normal intracellular transport mechanisms and leads to the accumulation of neuron-damaging clumps of protein associated with Parkinson's disease (PD), a neurodegenerative disorder that is characterized by a specific loss of neurons in the midbrain and brainstem. The research, published by Cell Press in the December 24 issue of the journal Neuron, identifies a new potential therapeutic option for preventing PD-associated neuropathology.

24 Dec 2009

Tips to minimize injuries during winter season

As we try to get outside and make the most of these cold winter months, it's important to use basic safety tips that help minimize injury. The Minnesota Chiropractic Association (MCA) offers the following tips to help keep your family injury free.

24 Dec 2009

Study evaluates anemia treatment approaches adopted by different specialists

BioTrends Research Group, Inc. published a syndicated research report, "TreatmentTrends®: Anemia in the United States," based on primary research conducted with approximately 400 physicians in clinical practice.

24 Dec 2009

Colcrys Patient Assistance Program introduced by URL Pharma

URL Pharma, Inc. announced the launch of the Colcrys® (colchicine, USP) Patient Assistance Program, an initiative that will allow patients with limited means to save on Colcrys prescriptions. This program reflects URL Pharma's ongoing commitment to helping ensure that all patients who rely on the company's medications are able to access them, regardless of economic status. Colcrys is indicated for the prevention and treatment of gout flares and for the treatment of Familial Mediterranean Fever (FMF).

24 Dec 2009

Rethink Autism offers research-based intervention tools for children with autism disorder

According to a study recently released by the Center for Disease Control and Prevention (CDC) and the Autism and Developmental Disabilities Monitoring Network, it is estimated that approximately 673,000 children aged 3-21 have been diagnosed with autism nationwide.

24 Dec 2009

Interdisciplinary approach essential for treating men’s' sexual dysfunction

Modern, couple-oriented treatment for male sexual dysfunction takes the psychosocial aspects of sex into account, as well as focussing on the purely physical aspects of the problem.

24 Dec 2009

FDA issues Pfizer a Complete Response letter for Lyrica GAD monotherapy treatment

Pfizer Inc. announced today that the Food and Drug Administration (FDA) issued a Complete Response letter regarding the company’s New Drug Application (NDA) for Lyrica® (pregabalin) capsules CV as a monotherapy treatment for generalized anxiety disorder (GAD). The FDA determined that the data contained in the NDA were insufficient to support approval.

24 Dec 2009

New compound may halt drug-resistant lung cancer

The ability to make, test, and map the atomic structure of new anti-cancer agents has enabled a team of Dana-Farber Cancer Institute scientists to discover a compound capable of halting a common type of drug-resistant lung cancer.

24 Dec 2009

Anti-inflammatory coxib medications inhibit aspirin's protective qualities

A new study conducted at Ben-Gurion University of the Negev (BGU) reveals that Celebrex and other anti-inflammatory coxib medications may counter the positive effects of aspirin in preventing blood clots.

24 Dec 2009

Study: Protein channel aids nerve sensors in controlling blood pressure

University of Iowa researchers have shown that a protein channel helps nerve sensors in blood vessels keep blood pressure in check. Without the protein channel, known as ASIC2, the sensors are unable to send the brain the signals it needs to properly control blood pressure.

24 Dec 2009

New energy receptor theory of brain function

Dr. Mitchell Earl Gibson, best-selling author, board-certified physician, and CEO of Tybro Publications, has proposed a new energy receptor theory of brain function that might explain the efficacy of mantras and prayer in human illness.

24 Dec 2009

Intervention strategy brings positive changes in type 2 diabetic patients

South Dakota State University research showed an intervention strategy based on the Native American spiritual concept of the Medicine Wheel brought positive changes for diabetics.

24 Dec 2009

Merck discontinues MK-1903 niacin receptor agonist development program with Arena Pharmaceuticals

Arena Pharmaceuticals, Inc. announced today Merck and Co., Inc.'s decision (through an affiliate) to discontinue development of MK-1903, an investigational niacin receptor agonist to treat atherosclerosis being developed under its research collaboration with Arena. Merck also informed Arena that the company will not continue the collaboration.

24 Dec 2009

Discovery enables scientists to devise novel strategies to diagnose and treat brain cancer

A team of Columbia scientists have discovered two genes that, when simultaneously activated, are responsible for the most aggressive forms of human brain cancer.

23 Dec 2009

Synta Pharmaceuticals initiates STA-9090 Phase 2 clinical trial for GIST

Synta Pharmaceuticals Corp., a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today announced that it is initiating a Phase 2 clinical study of STA-9090 in patients with advanced gastrointestinal stromal tumors (GIST). This is the sixth clinical study of STA-9090, a potent, synthetic, small molecule Hsp90 inhibitor with a novel chemical structure.

23 Dec 2009

Achievements in lupus research, education and advocacy cause for celebration and hope

The year 2009 will be remembered as a year of many firsts for lupus, including the first successful phase III clinical trial of a potential new treatment for lupus, the launch of the first-ever Ad Council public awareness campaign for lupus, and the first comprehensive report on the barriers to lupus drug development. And it appears there are no signs of any slowing of momentum as we enter the New Year.

23 Dec 2009

Protective benefits of Alzheimer's and cancer may lead to new diagnostic treatments

People who have Alzheimer's disease may be less likely to develop cancer, and people who have cancer may be less likely to develop Alzheimer's disease, according to a new study published in the December 23, 2009, online issue of Neurology®, the medical journal of the American Academy of Neurology.

23 Dec 2009

Thyroid cancer on the rise

As seen on "NBC Nightly News" Monday, December 21, the thyroid cancer rate is rising rapidly, especially among women. The American Thyroid Association's members are working to educate more people about thyroid cancer as well as treat and cure it.

23 Dec 2009

Gene's role in immune system may suggest new treatments for childhood asthma

Pediatric researchers have identified a novel gene involved in childhood asthma, in one of the largest gene studies to date of the common respiratory disease. Because the gene, called DENND1B, affects cells and signaling molecules thought to be instrumental in the immune system overreaction that occurs in asthma, the discovery may have singled out an important target for new treatments.

23 Dec 2009

Medical Condition News

Key molecular switch linked to HD identified

Potential new therapeutic option for prevention of PD-associated neuropathology

Tips to minimize injuries during winter season

Study evaluates anemia treatment approaches adopted by different specialists

Colcrys Patient Assistance Program introduced by URL Pharma

Rethink Autism offers research-based intervention tools for children with autism disorder

Interdisciplinary approach essential for treating men’s' sexual dysfunction

FDA issues Pfizer a Complete Response letter for Lyrica GAD monotherapy treatment

New compound may halt drug-resistant lung cancer

Anti-inflammatory coxib medications inhibit aspirin's protective qualities

Study: Protein channel aids nerve sensors in controlling blood pressure

New energy receptor theory of brain function

Intervention strategy brings positive changes in type 2 diabetic patients

Merck discontinues MK-1903 niacin receptor agonist development program with Arena Pharmaceuticals

Discovery enables scientists to devise novel strategies to diagnose and treat brain cancer

Synta Pharmaceuticals initiates STA-9090 Phase 2 clinical trial for GIST

Achievements in lupus research, education and advocacy cause for celebration and hope

Protective benefits of Alzheimer's and cancer may lead to new diagnostic treatments

Thyroid cancer on the rise

Gene's role in immune system may suggest new treatments for childhood asthma

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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