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Insights and new directions in basic, clinical research into neurodegenerative diseases

A special supplement to the Journal of Alzheimer's Disease, published by IOS Press, presents insights and new directions in both basic and clinical research into neurodegenerative diseases.

28 Sep 2023

New approach could improve immune checkpoint inhibitor response in MTAP-deficient tumors

Loss of the "housekeeping" gene methylthioadenosine phosphorylase, or MTAP, is a common event in cancer.

28 Sep 2023

Social isolation linked to higher depression levels during the COVID-19 pandemic

Higher levels of depressive symptoms have been reported during the COVID-19 pandemic compared with other times in history, and as much as three times higher than prior to the pandemic.

28 Sep 2023

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

In some patients, infection with the pandemic virus SARS-CoV-2 can trigger a dangerous immune response in hardened fatty deposits (plaques) lining the heart's largest blood vessels, a new study shows.

28 Sep 2023

Study focuses on empowering minoritized patients with chronic pain to receive best care

A new study led by a U.S. Department of Veterans Affairs, Regenstrief Institute and Indiana University School of Medicine researcher focuses on empowering minoritized patients with chronic back and other musculoskeletal pain to receive care best suited to their individual values and preferences.

28 Sep 2023

Brain compensation may delay worsening of Parkinson's symptoms

In Parkinson's disease, the cerebral cortex can take over tasks from a deeper part of the brain that has been damaged, where cells that make dopamine have been lost.

28 Sep 2023

Acute kidney injury patients on dialysis may be overtreated

Patients with acute kidney injury requiring outpatient dialysis after hospital discharge receive the same care as those with the more common end-stage kidney disease, according to a study led by UC San Francisco.

28 Sep 2023

Poll: Majority of older adults oppose use of life expectancy in cancer screening guidelines

A majority of older adults disagree with the idea of using life expectancy as part of guidelines that say which patients should get cancer screenings such as mammograms and colonoscopies, a new poll finds.

28 Sep 2023

Hospitalized COVID patients displayed multiple organ abnormalities five months after infection

A study looking at the longer-term impact of COVID-19 has found that nearly a third of patients displayed abnormalities in multiple organs five months after infection, some of which have been shown through previous work to be evidence of tissue damage.

28 Sep 2023

SARS-CoV-2 infects coronary vessels, inducing plaque inflammation

SARS-CoV-2, the virus that causes COVID-19, can directly infect the arteries of the heart and cause the fatty plaque inside arteries to become highly inflamed, increasing the risk of heart attack and stroke, according to a study funded by the National Institutes of Health.

28 Sep 2023

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.

28 Sep 2023

Canadian adults with cannabis use disorder appear to have 60% higher risk of cardiovascular diseases

A new study has found that Canadian adults with cannabis use disorder appear to have an approximately 60% higher risk of experiencing their first heart attack, stroke, or other major cardiovascular event than those without cannabis use disorder.

28 Sep 2023

Study uncovers previously unknown compensatory mechanism in liver disease

A team of researchers has uncovered a previously unknown compensatory mechanism found in liver disease.

28 Sep 2023

US health care workers are at greater risk of suicide than non–health care workers

The risks of death by suicide for six healthcare worker (HCW).

28 Sep 2023

Examining the cardiac pathology in fatal cases of yellow fever

The characteristics of yellow fever (YF)-related myocardial damage.

28 Sep 2023

New multi-polygenic scores boost coronary heart disease prediction accuracy

Two multi-polygenic scores (muti-PGs) to predict coronary heart disease (CHD).

28 Sep 2023

Can AI outperform radiologists in detecting lung issues? New study weighs in

New study in Radiology evaluates the diagnostic accuracy of four AI tools in detecting common acute findings on chest radiographs. While AI tools showed moderate to high sensitivity and strong negative predictive values, they had higher false-positive rates compared to traditional radiology reports.

28 Sep 2023

Non-alcoholic fatty liver disease linked to higher risk of blood clots in healthy adults

Recent study in Scientific Reports finds a link between nonalcoholic fatty liver disease (NAFLD) and a higher risk of venous thromboembolism (VTE) among healthy Korean adults. The research suggests that NAFLD may contribute to a hypercoagulable state, increasing the risk of VTE.

27 Sep 2023

Yeast in the gut linked to Crohn's disease inflammation, opening new doors for treatment

New study in Nature Medicine links yeast cells in the gastrointestinal tract to abnormal immune responses causing inflammation in Crohn's disease patients. The research suggests that these yeast-reactive T-cells could be a potential therapeutic target, offering new avenues for treatment.

27 Sep 2023

Self‐administration of investigational intranasal spray may be a new option to treat rapid heartbeat

A fast-acting medication delivered as a nasal spray may someday allow patients with intermittent rapid heartbeats to treat it themselves as soon as they develop symptoms, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

27 Sep 2023

Medical Condition News

Insights and new directions in basic, clinical research into neurodegenerative diseases

New approach could improve immune checkpoint inhibitor response in MTAP-deficient tumors

Social isolation linked to higher depression levels during the COVID-19 pandemic

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

Study focuses on empowering minoritized patients with chronic pain to receive best care

Brain compensation may delay worsening of Parkinson's symptoms

Acute kidney injury patients on dialysis may be overtreated

Poll: Majority of older adults oppose use of life expectancy in cancer screening guidelines

Hospitalized COVID patients displayed multiple organ abnormalities five months after infection

SARS-CoV-2 infects coronary vessels, inducing plaque inflammation

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Canadian adults with cannabis use disorder appear to have 60% higher risk of cardiovascular diseases

Study uncovers previously unknown compensatory mechanism in liver disease

US health care workers are at greater risk of suicide than non–health care workers

Examining the cardiac pathology in fatal cases of yellow fever

New multi-polygenic scores boost coronary heart disease prediction accuracy

Can AI outperform radiologists in detecting lung issues? New study weighs in

Non-alcoholic fatty liver disease linked to higher risk of blood clots in healthy adults

Yeast in the gut linked to Crohn's disease inflammation, opening new doors for treatment

Self‐administration of investigational intranasal spray may be a new option to treat rapid heartbeat

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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