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Study reveals molecular mechanism behind new DOT1L-related disorder

A study from the laboratory of Dr. Hugo J. Bellen, a distinguished service professor at Baylor College of Medicine and a principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, has discovered that gain-of-function variants in the DOT1L gene cause a new disorder.

13 Oct 2023

Deep brain stimulation improves memory and promotes neuron growth in Rett mice

A recent study from the lab of Dr. Jianrong Tang, associate professor at Baylor College of Medicine and principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital shows that deep brain stimulation (DBS) of a specific brain region results in a significant and sustained improvement of memory in Rett mice.

13 Oct 2023

New insights into coronavirus E channel could lead to antiviral drugs

The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages tissues and contributes to the symptoms of Covid-19.

13 Oct 2023

Strong antibody response and nasal cytokines may protect young children from severe COVID-19

New research helps explain why young children have lower rates of severe COVID-19 than adults. A study of infants and young children found those who acquired SARS-CoV-2 had a strong, sustained antibody response to the virus and high levels of inflammatory proteins in the nose but not in the blood.

13 Oct 2023

Scientists discover feedback loop that controls itch and inflammation

It can be a relief to scratch the occasional itch, but when itch gets out of control, it can become a serious health problem. How does the body know when to stop?

13 Oct 2023

Calorie restriction may rejuvenate muscles and activate biological pathways for healthy aging

Reducing overall calorie intake may rejuvenate your muscles and activate biological pathways important for good health, according to researchers at the National Institutes of Health and their colleagues.

13 Oct 2023

New technique to control severe bleeding increases risk of death, study finds

A new technique used to control severe bleeding in injured patients has been found to increase the risk of death, according to new research from the University of Aberdeen, in Scotland, which was led by University of Alabama at Birmingham trauma surgeon and professor Jan Jansen, Ph.D. Jansen was a surgeon and researcher in Aberdeen before moving to the United States in 2017.

13 Oct 2023

Dementia risk factors have greater impact on minority ethnic groups

Factors that increase the risk of dementia have a greater impact on risk for people in minority ethnic groups, finds a new study led by UCL researchers.

13 Oct 2023

Societies need to give clearer, explicit support for breastfeeding in public, researchers say

International law supports women's right to breastfeed in the public. However, women report having been subjected to negative responses and judgmental looks when breastfeeding outside the home.

13 Oct 2023

Opioid prescribing limits may not worsen patient experience after common surgeries

Worries that surgery patients would have a tougher recovery if their doctors had to abide by a five-day limit on opioid pain medication prescriptions didn't play out as expected, a new study finds.

13 Oct 2023

Nongenetic mechanisms play a role in lung cancer treatment resistance

In a recent study led by Ravi Salgia, M.D., Ph.D., the Arthur & Rosalie Kaplan Chair in Medical Oncology, a team of researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, and other institutions found that nongenetic mechanisms are important in lung cancer patients who develop a resistance to one cancer therapy.

13 Oct 2023

Study provides insights into atrial fibrillation detected after stroke

Worldwide, millions of stroke survivors undergo prolonged cardiac monitoring, leading to the discovery of atrial fibrillation, or irregular heartbeats, in up to 1.5 million of these patients each year.

13 Oct 2023

Study sheds new light on the relationship between autism traits and mental health in middle childhood

A long-term study by UC Davis Health researchers sheds new light on the relationship between autism traits and mental health in middle childhood.

13 Oct 2023

Grit and self-control linked to better weight loss outcomes in couples

New research has underscored how characteristics of "grit" and self-control are associated with better weight loss and weight maintenance outcomes in a study focusing on couples.

13 Oct 2023

Traffic air pollution linked to serious neonatal complications

Exposure to traffic-related air pollution during pregnancy is associated with serious neonatal complications, according to a study by UT Southwestern Medical Center researchers that matched records from more than 60,000 births with air-monitoring data.

13 Oct 2023

Study indicates a very high level of resilience among Canadians with arthritis

A new study published by researchers at the University of Toronto indicates a very high level of resilience among Canadians with arthritis whose activities were restricted due to pain.

13 Oct 2023

Tumor debulking does not impact quality of life in metastatic colorectal cancer, study finds

New research in the October 2023 issue of JNCCN - Journal of the National Comprehensive Cancer Network finds that intensive local-regional treatment to remove as much tumor as possible (known as "debulking"), in addition to standard systemic therapy, does not impact overall quality of life significantly for people with metastatic colorectal cancer.

13 Oct 2023

New study shows higher lung cancer incidence in women than in men

Reversing historical patterns, new findings led by researchers at the American Cancer Society (ACS) show higher lung cancer incidence in women than in men has not only continued in adults younger than 50 years, but now extends to women 50 to 54 years of age in the United States.

13 Oct 2023