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Chest wall irradiation does not impact 10-year survival in intermediate-risk breast cancer

Patients with intermediate-risk breast cancer had similar rates of 10-year overall survival whether or not they underwent chest wall irradiation (CWI) after mastectomy, according to results from the BIG 2-04 MRC SUPREMO clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

12 Dec 2024

Active monitoring for low-risk DCIS results in similar quality of life as standard treatment

Patients with low-risk ductal carcinoma in situ (DCIS) who underwent active monitoring reported comparable physical, emotional, and psychological outcomes to patients who received upfront treatment, according to results from the COMET clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

12 Dec 2024

COMET trial shows active monitoring is noninferior to standard treatment for low-risk DCIS

Among patients with hormone receptor (HR)-positive, HER2-negative, low-risk ductal carcinoma in situ (DCIS), those who underwent active monitoring had similar two-year invasive ipsilateral breast cancer recurrence rates as those who underwent guideline-concordant treatment, according to results from the COMET clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

12 Dec 2024

Study links early-life tonsil removal to long-term risk of stress-related disorders

Researchers explore the potential association between tonsillectomy and adenoid removal in the risk of developing stress-related disorders in later life.

12 Dec 2024

Virus causes 20 million infections annually as study uncovers hidden drivers of its evolution

Researchers describe the evolutionary origins of hepatitis E virus in rodents.

12 Dec 2024

How added sugars and sweetened foods impact the risk of 7 cardiovascular diseases

Researchers examine the risk of seven different types of cardiovascular diseases associated with added and free sugar in foods and beverages.

12 Dec 2024

Study sheds light on how deep sleep supports memory formation

It has been known for nearly 20 years that slow, synchronous electrical waves in the brain during deep sleep support the formation of memories.

12 Dec 2024

Surrey research offers new hope for people suffering from immunodeficiencies

Several rare immune disorders are caused by mutations in the patient's DNA. The University of Surrey and its collaborators found that targeting the mutated pathways with new drugs offers new hope for people suffering from rare conditions such as immunodeficiencies.

12 Dec 2024

Gene therapy to prevent stillbirth and premature delivery developed

Researchers investigate the effectiveness of placental nano-based insulin-like 1 growth factor gene therapy to correct fetal growth restriction.

12 Dec 2024

Common brain network connected to heterogeneous patterns of brain atrophy in schizophrenia

A new study led by investigators from Mass General Brigham has identified a unique brain network that links varied patterns of brain atrophy, or shrinkage, associated with schizophrenia.

12 Dec 2024

Addressing inequities in cardiovascular drug access

A new study assessing provincial and territorial variations in reimbursement criteria of drug coverage for patients covered by Canada's public pharmacare programs for two common cardiovascular conditions revealed significant inequities and deficiencies in access to medications and treatment.

12 Dec 2024

Widening childhood vaccination inequality in England raises concerns

Inequalities in childhood vaccination are widening in England, with uptake rates of five key vaccines consistently lower in young children living in areas of higher deprivation from 2019 to 2023, finds a study published by The BMJ today.

11 Dec 2024

Modified chemotherapy regimen for Hodgkin lymphoma reduces long-term side effects

A simple change to the chemotherapy regimen for people with Hodgkin lymphoma could reduce the long-term health impacts that can result from treatment, according to researchers in Cambridge.

11 Dec 2024

Gut-targeted antidepressants: A novel approach to battling depression and anxiety

Most of us have experienced the effects of moods and emotions on our gastrointestinal tract, from "butterflies" in the stomach caused by nervousness to a loss of appetite when we're feeling blue.

11 Dec 2024

Early smoking causes structural and functional heart damage

Cigarette smoking from childhood into early adulthood is associated with an increased risk of premature cardiac injury, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

11 Dec 2024

New insights into accelerated aging in young sickle cell patients

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 21 on November 14, 2024, entitled, "Adolescents and young adults with sickle cell disease exhibit accelerated aging with elevated T-cell p16INK4a expression."

11 Dec 2024

Scientists reveal the secret of female orgasm

The secret of the female orgasm may have been revealed by scientists in a pioneering study.

11 Dec 2024

Exosomes: A double-edged sword in hepatocellular carcinoma

The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of tumorigenesis, the TIME attempts to eliminate abnormal cells through immune surveillance.

11 Dec 2024

Skin-friendly bacteria could revolutionize vaccination

Imagine a world in which a vaccine is a cream you rub onto your skin instead of a needle a health care worker pushes into your one of your muscles.

11 Dec 2024

Blood pressure fluctuations linked to problems with thinking and memory skills

Older adults whose blood pressure fluctuates over time may be more likely to have problems with thinking and memory skills, according to a study published in the December 11, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

11 Dec 2024

Medical Research News

Chest wall irradiation does not impact 10-year survival in intermediate-risk breast cancer

Active monitoring for low-risk DCIS results in similar quality of life as standard treatment

COMET trial shows active monitoring is noninferior to standard treatment for low-risk DCIS

Study links early-life tonsil removal to long-term risk of stress-related disorders

Virus causes 20 million infections annually as study uncovers hidden drivers of its evolution

How added sugars and sweetened foods impact the risk of 7 cardiovascular diseases

Study sheds light on how deep sleep supports memory formation

Surrey research offers new hope for people suffering from immunodeficiencies

Gene therapy to prevent stillbirth and premature delivery developed

Common brain network connected to heterogeneous patterns of brain atrophy in schizophrenia

Addressing inequities in cardiovascular drug access

Widening childhood vaccination inequality in England raises concerns

Modified chemotherapy regimen for Hodgkin lymphoma reduces long-term side effects

Gut-targeted antidepressants: A novel approach to battling depression and anxiety

Early smoking causes structural and functional heart damage

New insights into accelerated aging in young sickle cell patients

Scientists reveal the secret of female orgasm

Exosomes: A double-edged sword in hepatocellular carcinoma

Skin-friendly bacteria could revolutionize vaccination

Blood pressure fluctuations linked to problems with thinking and memory skills

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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