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Patterns of philopatry and longevity contribute to menopause, study suggests

The evolution of the menopause was 'kick-started' by a fluke of nature, but then boosted by the tendency for sons and grandsons to remain living close to home, a new study by Liverpool scientists suggests.

17 Feb 2016

New optogenetic technology could turn on immune cells to attack melanoma tumors

A new optogenetic technology developed at UMass Medical School, called optogenetic immunomodulation, is capable of turning on immune cells to attack melanoma tumors in mice. Using near-infrared light, UMMS researchers have shown they can selectively activate an immune response by controlling the flow of calcium ions into the cell. This breakthrough could lead to less invasive, and more controlled and selective, immunotherapies for cancer treatment.

17 Feb 2016

Study: Many school children avoid basic foods due to perceived hypersensitivity

A study on hypersensitivity to the basic foods milk, egg, fish and wheat among young school children showed that reported food hypersensitivity was eight times more common than allergies confirmed by allergy tests. This according to a new dissertation at Umeå University.

17 Feb 2016

NUS-led study reveals key player contributing to maintenance of hematopoietic stem cells

A study led by scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has uncovered a key player contributing to the maintenance of hematopoietic stem cells (HSCs), blood cell precursors which have the ability to become any type of blood cell in the body.

17 Feb 2016

FAU researchers find mechanism that promotes metastasis and causes tumours to resist treatment

Fast metastasis and resistance to treatment are characteristic of aggressive types of cancer such as pancreatic cancer and certain kinds of breast cancer. They are also the main causes of cancer-related death, as there is currently no specific treatment available that is able to stop tumours spreading throughout the whole body. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have recently made a discovery that could change this.

17 Feb 2016

Wistar researchers find potential way for using STAT3 inhibitors to stop cancer progression

Imagine developing a drug designed to inhibit a protein that helps cancer cells proliferate and survive only to find that the drug does not perform very well in the clinic. This was the dilemma faced by scientists researching inhibitors of signal transducer and activator of transcription (STAT3), a protein that controls transcription by the STAT3 gene.

17 Feb 2016

Small chemical change to existing antibacterial drug may result in better treatment for TB

Researchers with Vanderbilt University have discovered that one small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis.

17 Feb 2016

High salt and sodium intake persists in China: Study

Yongning Wu, Ph.D., of the China National Centre for Food Safety Risk Assessment, Beijing, China, and colleagues compared salt and sodium consumption in China in 2000 with 2009-2012. The study appears in the February 16 issue of JAMA.

17 Feb 2016

First-of-its-kind project focuses on farming communities and dementia

Dementia is a growing health problem, with an anticipated increase in the number of cases in the UK of 156 per cent between now and 2051, according to statistics from the Alzheimer's Society.

17 Feb 2016

Current evidence insufficient to assess benefits and harms of screening for ASD

The U.S. Preventive Services Task Force has concluded that the current evidence is insufficient to assess the balance of benefits and harms of screening for autism spectrum disorder (ASD) in children 18 to 30 months of age for whom no concerns of ASD have been raised by their parents or a clinician.

17 Feb 2016

Isomaltulose more suitable than table sugar for people with type 2 diabetes

Potsdam-Rehbruecke - Like sucrose (table sugar), the natural disaccharide isomaltulose (PalatinoseTM) consists of glucose and fructose, but it is apparently more suitable for people with type 2 diabetes with regard to regulating blood glucose levels.

17 Feb 2016

Small peptide TAxI holds promise for carrying biologic drugs into spinal cord

A small peptide dubbed TAxI is living up to its name. Recent studies show it to be an effective vehicle for shuttling functional proteins, such as active enzymes, into the spinal cord after a muscle injection.

17 Feb 2016

Study reveals another clue to workings of trachoma

Another clue to the workings of trachoma - the world's leading infectious cause of blindness - has been revealed in a new study published in BMC Infectious Diseases. Researchers identified markers of genetic regulation present in the early stages of infection that could predispose children to developing the condition in its long-term, severe form.

17 Feb 2016

New study could help explain critical shortcomings in stem cell-driven therapies for heart disease

With every heart attack, billions of cardiomyocytes, the contracting heart muscle cells that make the heart pump time after time over a lifetime, are lost which can lead to heart failure or injury. Stem cell-based replacement strategies could open new and much needed therapeutic avenues.

17 Feb 2016

Overcrowding appears to contribute to adverse events in Israeli inpatient psychiatric wards

Overcrowding is a common problem in Israeli inpatient psychiatric wards, and appears to contribute to higher rates of problem incidents--including falls and aggressive behavior, reports a study in the March issue of Medical Care.

17 Feb 2016

Green tea compound has high potential as treatment for rheumatoid arthritis

Researchers at Washington State University in Spokane have identified a potential new approach to combating the joint pain, inflammation and tissue damage caused by rheumatoid arthritis.

17 Feb 2016

Synthetic RNA and DNA could reverse protein deficiency that causes Friedreich's ataxia

Researchers at UT Southwestern Medical Center have identified synthetic RNA and DNA that reverses the protein deficiency causing Friedreich's ataxia, a neurological disease for which there is currently no cure.

17 Feb 2016

Physical therapy reduces urinary problems in postmenopausal women with osteoporosis

After menopause, women with osteoporosis struggle more with urinary incontinence than women with healthy bones do. But physical therapy that includes pelvic floor muscle training can produce dramatic improvements, shows a study published online today in Menopause, the journal of The North American Menopause Society.

17 Feb 2016

Photos and music can reduce anxiety for surgery patients

A new study found that viewing photographs combined with listening to music can less patients' anxiety before surgical operations and improve their physical and psychological well-being.

17 Feb 2016

Study shows new RNA letter as regulatory key to control gene expression

DNA, RNA, protein -- the end. Or is it? Until recently, the pattern used to encode genetic information into our cells was considered to be relatively straightforward: four letters (A,G,C,T) for DNA and four (A,G,C,U) for RNA. This equation, however, turned out to be oversimplified -- RNA was holding out.

17 Feb 2016

Medical Research News

Patterns of philopatry and longevity contribute to menopause, study suggests

New optogenetic technology could turn on immune cells to attack melanoma tumors

Study: Many school children avoid basic foods due to perceived hypersensitivity

NUS-led study reveals key player contributing to maintenance of hematopoietic stem cells

FAU researchers find mechanism that promotes metastasis and causes tumours to resist treatment

Wistar researchers find potential way for using STAT3 inhibitors to stop cancer progression

Small chemical change to existing antibacterial drug may result in better treatment for TB

High salt and sodium intake persists in China: Study

First-of-its-kind project focuses on farming communities and dementia

Current evidence insufficient to assess benefits and harms of screening for ASD

Isomaltulose more suitable than table sugar for people with type 2 diabetes

Small peptide TAxI holds promise for carrying biologic drugs into spinal cord

Study reveals another clue to workings of trachoma

New study could help explain critical shortcomings in stem cell-driven therapies for heart disease

Overcrowding appears to contribute to adverse events in Israeli inpatient psychiatric wards

Green tea compound has high potential as treatment for rheumatoid arthritis

Synthetic RNA and DNA could reverse protein deficiency that causes Friedreich's ataxia

Physical therapy reduces urinary problems in postmenopausal women with osteoporosis

Photos and music can reduce anxiety for surgery patients

Study shows new RNA letter as regulatory key to control gene expression

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