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Study shows how gut bacteria can affect normal brain activity

The hundred trillion bacteria living in an adult human--mostly in the intestines, making up the gut microbiome--have a significant impact on behavior and brain health. The many ways gut bacteria can impact normal brain activity and development, affect sleep and stress responses, play a role in a variety of diseases, and be modified through diet for therapeutic use are described in a comprehensive Review article in Journal of Medicinal Food, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

23 Jan 2015

New research could help pave way to new cancer therapies

New research from the Hebrew University of Jerusalem shows that the most common form of white blood cells, called neutrophils, contain many different subtypes, of which some fight the development of cancer and others promote its progression. The research could help pave the way to new therapies that fight cancer by increasing anti-tumor neutrophils while limiting pro-tumor neutrophils.

23 Jan 2015

Altered AHNAK gene may open door to improved treatment for keloid scars

Researchers at Henry Ford Hospital in Detroit have identified a gene that may offer a better understanding of how keloid scars develop and potentially open the door to improved treatment for the often painful, itchy and tender scars.

23 Jan 2015

Heptares Therapeutics announces recipients of Malcolm Campbell Memorial Prize for 2015

Heptares Therapeutics, the clinical-stage GPCR structure-guided drug discovery and development company, is delighted to announce that the Malcolm Campbell Memorial Prize for 2015 has been awarded to Miles Congreve (Vice President of Chemistry), Fiona Marshall (Chief Scientific Officer and co-founder) and Malcolm Weir (Chief Executive Officer and co-founder) for the seminal contributions to GPCR drug discovery made by Heptares Therapeutics since the company was founded in 2007.

23 Jan 2015

TxCell to highlight success factors in cell therapy research at Cell & Gene Therapy Forum 2015

TxCell SA, a biotechnology company developing innovative, cost-effective, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that Dr. Miguel Forte, Sr. VP Clinical Development and Regulatory Affairs, TxCell, will present at the Cell & Gene Therapy Forum 2015, January 26 - 28, 2015 at Grand Hayatt in Washington DC, United States.

23 Jan 2015

Cardiac regeneration strategies need to be based on severity of heart injury

A new study by researchers at Children's Hospital Los Angeles has shown that neonatal mouse hearts have varying regenerative capacities depending upon the severity of injury. Using cryoinjury - damaging the heart through exposure to extreme cold in order to mimic cellular injury caused by myocardial infarction - investigators found that neonatal mouse hearts can fully recover normal function following a mild injury, though fail to regenerate after a severe injury.

23 Jan 2015

Thyroid disease can affect woman's reproductive health

Thyroid disease can have significant effects on a woman's reproductive health and screening for women presenting with fertility problems and recurrent early pregnancy loss should be considered, suggests a new review published today (23 January) in The Obstetrician & Gynaecologist.

23 Jan 2015

Study uses 'systems genetics' approach to identify potential target for epilepsy

A single gene that coordinates a network of about 400 genes involved in epilepsy could be a target for new treatments, according to research.

23 Jan 2015

International study identifies genetic factors that influence the size of brain structures

An international study, which included researchers from NUI Galway, has identified significant genetic factors that influence the size of structures within the brain. It is hoped these new insights may help scientists better understand disorders such as schizophrenia, Alzheimer's disease and epilepsy.

23 Jan 2015

New Baylor research explores novel non-invasive technology for pediatric eye exams

Picture a toddler getting his first eye exam. He's seated in a strange room, with strange instruments and strange bright lights. He can't sit still or open his eyes long enough for that diagnostic poof of air - especially if he has trouble seeing anyway, as children with achromatopsia do.

23 Jan 2015

PKC enzymes categorized as cancer promoters are actually tumor suppressors

Upending decades-old dogma, a team of scientists at the University of California, San Diego School of Medicine say enzymes long categorized as promoting cancer are, in fact, tumor suppressors and that current clinical efforts to develop inhibitor-based drugs should instead focus on restoring the enzymes' activities.

23 Jan 2015

Scientists identify new molecular pathway that controls axonal degeneration following injury

Axons connect neurons with each other to form the neural networks that underpin the vital functions of perception, motility, cognition, and memory. In many neurodegenerative disorders, from traumatic injury or toxic damage to diseases such as Alzheimer's or Parkinson's disease, axonal degeneration represents an essential pathological feature.

23 Jan 2015

New discovery may help doctors develop better treatments for brain, spinal cord injuries

In a discovery that could dramatically affect the treatment of brain and spinal cord injuries, researchers have identified a previously unknown, beneficial immune response that occurs after injury to the central nervous system.

23 Jan 2015

Scientists identify gene that helps regulate development of central nervous system

Scientists have identified a gene that helps regulate how well nerves of the central nervous system are insulated, researchers at Washington University School of Medicine in St. Louis report.

23 Jan 2015

Study finds relationship between menopausal symptoms, bone health in postmenopausal women

The first large prospective cohort study to examine the relationship between menopausal symptoms and bone health in postmenopausal women has found that those who experience moderate to severe hot flashes and night sweats during menopause tend to have lower bone mineral density and higher rates of hip fracture than peers with no menopausal symptoms.

23 Jan 2015

Monell Center receives NIH grant to develop clinical tool that can predict anosmia

Monell Center scientist Kai Zhao, PhD, is principal investigator on a $1.5M 4-year grant from the National Institute on Deafness and Other Communication Disorders, part of the National Institutes of Health, to further develop clinical methodology that can predict the path of air flow through a person's nasal passages.

23 Jan 2015

UCLA researchers find new treatment that restores normal social behavior in autism mice model

Among the problems people with Autism spectrum disorders (ASD) struggle with are difficulties with social behavior and communication. That can translate to an inability to make friends, engage in routine conversations, or pick up on the social cues that are second nature to most people. Similarly, in a mouse model of ASD, the animals, like humans, show little interest in interacting or socializing with other mice.

23 Jan 2015

Voices of loved ones telling familiar stories can help awaken unconscious brain, speed coma recovery

"Can he hear me?" family members are desperate to know when a loved one with a traumatic brain injury is in a coma.

23 Jan 2015

Childbearing women who take painkillers may face increased risk of birth defects

More than one-fourth of privately-insured and one-third of Medicaid-enrolled women of childbearing age filled prescriptions for opioid-based (narcotic) painkillers between 2008 and 2012, according to a new analysis published today by the U.S. Centers for Disease Control and Prevention in its Morbidity and Mortality Weekly Report (MMWR).

23 Jan 2015

Findings could lead to new therapeutic approach to Parkinson's disease

E.. coli usually brings to mind food poisoning and beach closures, but researchers recently discovered a protein in E.. coli that inhibits the accumulation of potentially toxic amyloids--a hallmark of diseases such as Parkinson's.

23 Jan 2015

Medical Research News

Study shows how gut bacteria can affect normal brain activity

New research could help pave way to new cancer therapies

Altered AHNAK gene may open door to improved treatment for keloid scars

Heptares Therapeutics announces recipients of Malcolm Campbell Memorial Prize for 2015

TxCell to highlight success factors in cell therapy research at Cell & Gene Therapy Forum 2015

Cardiac regeneration strategies need to be based on severity of heart injury

Thyroid disease can affect woman's reproductive health

Study uses 'systems genetics' approach to identify potential target for epilepsy

International study identifies genetic factors that influence the size of brain structures

New Baylor research explores novel non-invasive technology for pediatric eye exams

PKC enzymes categorized as cancer promoters are actually tumor suppressors

Scientists identify new molecular pathway that controls axonal degeneration following injury

New discovery may help doctors develop better treatments for brain, spinal cord injuries

Scientists identify gene that helps regulate development of central nervous system

Study finds relationship between menopausal symptoms, bone health in postmenopausal women

Monell Center receives NIH grant to develop clinical tool that can predict anosmia

UCLA researchers find new treatment that restores normal social behavior in autism mice model

Voices of loved ones telling familiar stories can help awaken unconscious brain, speed coma recovery

Childbearing women who take painkillers may face increased risk of birth defects

Findings could lead to new therapeutic approach to Parkinson's disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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