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Herpes infections soar globally as new study reveals massive disease burden

Global estimates of HSV-1 and HSV-2 reveal a staggering disease burden, with 42.4 million new genital herpes cases and 8.8 billion GUD person-days in 2020, underscoring the urgent need for improved prevention strategies.

12 Dec 2024

Lipid imbalances hold the key to chronic inflammation in colon cancer

Scientists uncover how disrupted lipid metabolism fuels chronic inflammation in colorectal cancer, offering insights into new therapeutic strategies targeting pro-inflammatory and pro-resolving lipid imbalances.

12 Dec 2024

Metabolomic biomarkers improve diabetes risk prediction accuracy

Researchers developed a novel diabetes risk score integrating traditional factors with metabolomic biomarkers, achieving improved prediction accuracy for 10-year type 2 diabetes risk.

12 Dec 2024

Insilico Medicine gets first clinical milestone payment of $10 million for XL309

Insilico Medicine ('Insilico'), a clinical-stage generative artificial intelligence (AI)-driven drug discovery and development company, today announced that it has received the first clinical milestone payment of $10 million for XL309 (previously known as ISM3091) from Exelixis.

12 Dec 2024

Fatty acids disrupt glutamate transporter function in brain cells

Glutamate transporters pump glutamate from the synaptic cleft back into brain cells after its release during neurotransmission.

12 Dec 2024

New study challenges traditional view of how the genetic code evolved

Despite awe-inspiring diversity, nearly every lifeform – from bacteria to blue whales – shares the same genetic code. How and when this code came about has been the subject of much scientific controversy.

12 Dec 2024

New study identifies potential target for treating diabetic cardiomyopathy

Some patients with diabetes develop a serious condition known as diabetic cardiomyopathy, which is slow and cannot be directly attributed to hypertension or other cardiovascular disorders.

12 Dec 2024

Mediterranean plants show promise for cardiovascular disease treatment

A study initiated from a final degree project at the Universitat Autònoma de Barcelona, with the involvement of researchers from the INc-UAB, the University of Barcelona and Cuban and Chilean institutions, has resulted in an exhaustive bibliographic review of a group of Mediterranean plants, whose active principles are attributed pharmacological actions in the field of cardiovascular diseases most affecting the population.

12 Dec 2024

Study uncovers brain mechanism behind empathetic responses

A specific brain mechanism modulates how animals respond empathetically to others' emotions. This is the latest finding from the research unit Genetics of Cognition, led by Francesco Papaleo, Principal Investigator at the Istituto Italiano di Tecnologia (IIT - Italian Institute of Technology) and affiliated with IRCCS Ospedale Policlinico San Martino in Genova.

12 Dec 2024

Study links early-life tonsil removal to long-term risk of stress-related disorders

Researchers explore the potential association between tonsillectomy and adenoid removal in the risk of developing stress-related disorders in later life.

12 Dec 2024

Virus causes 20 million infections annually as study uncovers hidden drivers of its evolution

Researchers describe the evolutionary origins of hepatitis E virus in rodents.

12 Dec 2024

Deep Science Ventures and General Inception collaborate to create fibrosis-focused therapeutics company

Deep Science Ventures, a UK-based venture studio, and General Inception, a US-based venture studio, today announced a collaboration to create a company focused on developing novel treatments for fibrosis.

12 Dec 2024

How added sugars and sweetened foods impact the risk of 7 cardiovascular diseases

Researchers examine the risk of seven different types of cardiovascular diseases associated with added and free sugar in foods and beverages.

12 Dec 2024

Study sheds light on how deep sleep supports memory formation

It has been known for nearly 20 years that slow, synchronous electrical waves in the brain during deep sleep support the formation of memories.

12 Dec 2024

Surrey research offers new hope for people suffering from immunodeficiencies

Several rare immune disorders are caused by mutations in the patient's DNA. The University of Surrey and its collaborators found that targeting the mutated pathways with new drugs offers new hope for people suffering from rare conditions such as immunodeficiencies.

12 Dec 2024

Gene therapy to prevent stillbirth and premature delivery developed

Researchers investigate the effectiveness of placental nano-based insulin-like 1 growth factor gene therapy to correct fetal growth restriction.

12 Dec 2024

Common brain network connected to heterogeneous patterns of brain atrophy in schizophrenia

A new study led by investigators from Mass General Brigham has identified a unique brain network that links varied patterns of brain atrophy, or shrinkage, associated with schizophrenia.

12 Dec 2024

Implantable sensors aid in optimizing bone injury recovery

Tiny implantable sensors are helping University of Oregon researchers optimize the process of recovery from severe bone injuries.

12 Dec 2024

New hepatitis B vaccine offers superior protection for people with HIV

A newer vaccine against hepatitis B virus was clearly superior to an older vaccine type in inducing a protective antibody response among people living with HIV who didn't respond to prior vaccination, according to the results of an international study led by a Weill Cornell Medicine investigator.

11 Dec 2024

Gut-targeted antidepressants: A novel approach to battling depression and anxiety

Most of us have experienced the effects of moods and emotions on our gastrointestinal tract, from "butterflies" in the stomach caused by nervousness to a loss of appetite when we're feeling blue.

11 Dec 2024