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UVA researchers discover how blood pressure medications affect kidneys

University of Virginia School of Medicine researchers have discovered how long-term treatment of high blood pressure with commonly prescribed drugs can destroy the kidney's ability to filter and purify blood.

21 Nov 2024

Natural fat molecule shows promise for treating diabetic heart disease

Monash University drug discovery researchers have found that a natural fat molecule called ‘lipoxin A4’ (LXA4) could significantly reduce inflammation and improve function for diabetic hearts.

21 Nov 2024

Researchers reveal cellular foundations of functional brain networks in humans

Rutgers researchers at the Brain Health Institute (BHI) and Center for Advanced Human Brain Imaging Research (CAHBIR) have uncovered how different types of brain cells work together to form large-scale functional networks in the human brain – interconnected systems that support everything from sensory processing to complex decision-making – paving the way for new insights into brain health and disease.

21 Nov 2024

CU Boulder study sheds light on sex differences in sleep patterns

Females sleep less, wake up more often and get less restorative sleep than males, according to a new animal study by CU Boulder researchers.

21 Nov 2024

Exploring how biological clocks measure aging and predict mortality

This review was published by Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), in Volume 16, Issue 17, titled, "A systematic review of phenotypic and epigenetic clocks used for aging and mortality quantification in humans."

21 Nov 2024

Ingestible capsule releases a burst of drugs directly into the walls of the GI tract

Inspired by the way that squids use jets to propel themselves through the ocean and shoot ink clouds, researchers from MIT and Novo Nordisk have developed an ingestible capsule that releases a burst of drugs directly into the wall of the stomach or other organs of the digestive tract.

21 Nov 2024

Electrical stimulation may be essential for healthy tendons, study suggests

A new study by researchers at the University of Galway and the University of Limerick suggests that electrical stimulation might be essential for tendons to maintain their health, offering fresh possibilities in tendon repair and regeneration.

21 Nov 2024

Breakthrough discovery could lead to novel malaria vaccines and therapies

Malaria, particularly in its severe forms, remains a global health and economic burden. It causes the deaths of more than 600,000 people every year – most of them African children under five.

21 Nov 2024

Small brain-penetrating molecule offers hope for treating aggressive brain tumors

Gliocidin selectively kills glioblastoma cells by inhibiting nucleotide synthesis, showing potential as a therapeutic option in combination with temozolomide.

21 Nov 2024

Camouflage detection boosts neural networks for brain tumor diagnosis

Research shows that CNNs trained on camouflage detection improve brain tumor classification in MRI scans, highlighting the potential of unconventional training.

21 Nov 2024

Saliva microbes differ in pregnant women with stress and mental health symptoms

Research links oral cavity microbes to maternal mental health, revealing potential interventions during pregnancy to enhance psychological well-being.

21 Nov 2024

New molecule promotes gut healing and suppresses tumor growth in colorectal cancer

Researchers at Karolinska Institutet have found a molecule that can both help the intestines to heal after damage and suppress tumor growth in colorectal cancer.

21 Nov 2024

Study projects global antibiotic use to rise by over 50% by 2030

A study reveals a 20.9% rise in global antibiotic use from 2016 to 2023, with middle-income countries leading the increase and highlighting resistance issues.

21 Nov 2024

Rare genetic mutations in healthy women may be key to breast cancer origins

Researchers at the University of British Columbia (UBC), BC Cancer, Harvard Medical School and Memorial Sloan Kettering Cancer Center (MSK) have pinpointed what could be the early genetic origins of breast cancer - cancer-like mutations appearing in the cells of healthy women.

21 Nov 2024

New atlas maps 1.6 million human gut cells in unprecedented detail

The most comprehensive cell map of the human gut to date has been created by combining spatial and single-cell data from 1.6 million cells.

21 Nov 2024

Pcdh8 gene suppression critical for zebrafish notochord formation

Can a single protein-encoding gene determine whether a vertebrate embryo develops normally? Yes, according to Osaka Metropolitan University researchers, who found that suppression of Pcdh8 is essential for the notochord to elongate properly in zebrafish.

21 Nov 2024

Electrical stimulation of vagus nerve could combat inflammatory bowel disease

Researchers at Duke University School of Medicine have found that tapping into the nervous system could help reduce the gut inflammation that drives inflammatory bowel disease (IBD).

20 Nov 2024

Jaw muscle size linked to sarcopenia risk in older adults

As populations age, the prevalence of sarcopenia - a progressive loss of muscle mass and function - has become an increasingly urgent public health concern. Sarcopenia increases the risk of falls and frailty, reduces the quality of life for older adults, and heightens the likelihood of requiring long-term care. Preventing sarcopenia is, therefore, crucial for alleviating this healthcare burden.

20 Nov 2024

Rethinking dairy: Whole milk tied to healthier weight profiles

Whole milk intake is associated with lower body weight, BMI, and obesity risk in U.S. adults. This study challenges traditional low-fat dairy guidelines and highlights whole milk's potential role in healthy weight management.

20 Nov 2024

Decoding the genetic roots of stroke and heart attack

In a new study published in the European Heart Journal, researchers at Karolinska Institutet show that genetic traits influence the cellular composition of atherosclerotic plaques, which over time will affect the risk of such lesions to cause a stroke or heart attack. The new knowledge can be used to improve the risk assessment and treatment of patients with atherosclerosis in the future.

20 Nov 2024