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Researchers identify strategies to mitigate disturbed axonal transport in ALS patients

A team of researchers at VIB and KU Leuven used stem cell technology to generate motor neurons from ALS patients carrying mutations in FUS. They found disturbed axonal transport in these motor neurons, but also identified genetic and pharmacological strategies that mitigate this defect.

17 Oct 2017

USC study reveals how schizophrenia has biological effect on the entire brain

Some 40 years since CT scans first revealed abnormalities in the brains of schizophrenia patients, international scientists say the disorder is a systemic disruption to the brain's entire communication system.

17 Oct 2017

Discovery may lead to new approach for treating MS

Around 2.5 million people are affected by the autoimmune disease Multiple Sclerosis (MS), the commonest central nervous system disease among young adults.

17 Oct 2017

Novel gene expression signature assay could help enhance lymphoma management

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer and the most frequently diagnosed non-Hodgkin lymphoma worldwide (nearly 40% of cases). Recent advancements indicate that both the prognosis and choice of treatment of DLBCL may depend on identifying its molecular subtype.

17 Oct 2017

CHOP researchers discover key differences among gene fusions in childhood brain tumors

Researchers investigating pediatric low-grade gliomas, the most common type of brain tumor in children, have discovered key biological differences in how mutated genes combine with other genes to drive this childhood cancer.

17 Oct 2017

Dietary combination transforms lethal breast cancers into highly treatable form

Researchers at the University of Alabama at Birmingham have found a dietary combination that transforms the most lethal of all breast cancers into a highly treatable breast cancer.

17 Oct 2017

Scientists discover new non-genetic cause of resistance to anti-cancer therapies

The targeted anti-cancer therapies cetuximab and panitumumab are mainstays of treatment for advanced colorectal cancer, the second leading cause of cancer-related deaths in the United States.

16 Oct 2017

Findings reveal how seizures can have lasting detrimental effects on memory

Although it's been clear that seizures are linked to memory loss and other cognitive deficits in patients with Alzheimer's disease, how this happens has been puzzling. In a study published in the journal Nature Medicine, a team of researchers reveals a mechanism that can explain how even relatively infrequent seizures can lead to long-lasting cognitive deficits in animal models.

16 Oct 2017

Stress may just as harmful to our body as bad diet, BYU study finds

We all know that a poor diet is unhealthy, but a new BYU study finds that stress may just as harmful to our bodies as a really bad diet.

16 Oct 2017

BU researcher wins NIH award for research on molecular mechanism of senile cardiac amyloidosis

Lawreen H. Connors, PhD, associate professor of pathology and laboratory medicine and biochemistry at Boston University School of Medicine, is the recipient of a National Institutes of Health High Priority, Short-Term Project Award, for her research "molecular mechanism of senile cardiac amyloidosis."

16 Oct 2017

Einstein scientists share $9 million NIH grant for longevity research

Scientists now believe that the Fountain of Youth flows from our genes, or at least from the genes of people who live healthy lives to age 100 or later.

16 Oct 2017

Powering up fat cells could help acute myeloid leukemia patients

Killing cancer cells indirectly by powering up fat cells in the bone marrow could help acute myeloid leukemia patients, according to a new study from McMaster University.

16 Oct 2017

Study identifies new biomarker for depression in diabetes

A study published in the current issue of Psychotherapy and Psychosomatic has identified a biomarker for depression in diabetes. Findings of epidemiological studies have shown an overall 2-fold increased prevalence of depression in patients with type 2 diabetes compared with the general population worldwide.

16 Oct 2017

Endogenous infection marker can help guide antibiotic use

The endogenous infection marker procalcitonin can help to guide the use of antibiotics when treating infections. The course of antibiotic therapy is shortened, and its side effects and mortality rate also decrease, as researchers from the University of Basel and other colleagues report in the journal The Lancet Infectious Diseases.

16 Oct 2017

Anti-hypertensive treatments do not restore microvascular function

Treatments for high blood pressure do not totally reverse its damaging effects on the vascular rhythms that help circulation of the blood say researchers.

16 Oct 2017

Researchers to investigate cellular changes leading to development of glioblastoma

Glioblastoma is the most common of malign brain tumors in adults, and it currently has no cure. Now a research team led by Dr Claudia Barros, from the Plymouth University Peninsula Schools of Medicine and Dentistry and its Brain Tumour Research-funded Centre of Excellence, has secured funding from the Brain Research Trust, which will help to expose novel molecules and their modes of action responsible for the initiation and growth of the disease.

16 Oct 2017

Study finds link between sleep duration and measure of chromosomal health in sperm

A new study found a link between sleep duration and a measure of chromosomal health in sperm. The findings are published in the Journal of Sleep Research.

16 Oct 2017

Scientists validate biomarker indicative of brain cancer patient's prognosis and drug response

Scientists at the Icahn School of Medicine at Mount Sinai, Sema4, and collaborating institutions including Colorado State University and Fred Hutchinson Cancer Center reported results today from a glioblastoma study in which they validated a biomarker indicative of a patient's prognosis and likely response to specific therapies.

16 Oct 2017

Researchers identify several previously unknown antibiotic resistance genes

Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have found several previously unknown genes that make bacteria resistant to last-resort antibiotics.

16 Oct 2017

Researchers identify new molecular pathway that controls aging in worms

Investigators at Case Western Reserve University School of Medicine and University Hospitals Health System have identified a new molecular pathway that controls lifespan and healthspan in worms and mammals.

13 Oct 2017

Medical Science News

Researchers identify strategies to mitigate disturbed axonal transport in ALS patients

USC study reveals how schizophrenia has biological effect on the entire brain

Discovery may lead to new approach for treating MS

Novel gene expression signature assay could help enhance lymphoma management

CHOP researchers discover key differences among gene fusions in childhood brain tumors

Dietary combination transforms lethal breast cancers into highly treatable form

Scientists discover new non-genetic cause of resistance to anti-cancer therapies

Findings reveal how seizures can have lasting detrimental effects on memory

Stress may just as harmful to our body as bad diet, BYU study finds

BU researcher wins NIH award for research on molecular mechanism of senile cardiac amyloidosis

Einstein scientists share $9 million NIH grant for longevity research

Powering up fat cells could help acute myeloid leukemia patients

Study identifies new biomarker for depression in diabetes

Endogenous infection marker can help guide antibiotic use

Anti-hypertensive treatments do not restore microvascular function

Researchers to investigate cellular changes leading to development of glioblastoma

Study finds link between sleep duration and measure of chromosomal health in sperm

Scientists validate biomarker indicative of brain cancer patient's prognosis and drug response

Researchers identify several previously unknown antibiotic resistance genes

Researchers identify new molecular pathway that controls aging in worms

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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