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Mitochondrial Pyruvate Carrier could potentially be a new drug target to treat diabetes

High blood sugar is a defining characteristic of Type 2 diabetes and the cause of many of the condition's complications, including kidney failure, heart disease, and blindness. Most diabetes medications aim to maintain normal blood sugar (glucose) levels and prevent high blood sugar by controlling insulin.

3 Sep 2015

First ever SNP array optimized for Japanese population

A research group, led by Professor Masao Nagasaki and Senior Assistant Professor Yosuke Kawai at Tohoku University Tohoku Medical Megabank Organization, has successfully designed the first ever SNP array that has been optimized for the Japanese population.

3 Sep 2015

Valerion announces positive results from non-clinical pilot study of VAL-1221 for treatment of Pompe disease

Valerion Therapeutics, LLC yesterday announced positive results from a non-clinical "proof of concept" pilot study for a novel humanized antibody and acid alpha glucosidase (GAA) fusion candidate for the treatment of Pompe disease.

3 Sep 2015

Regulatory T cells may reduce susceptibility to allergies

Susceptibility to allergies reduced by increased production of regulatory T cells. This is the main finding of a current study being conducted at the Institute of Immunology at MedUni Vienna, headed up by Winfried F. Pickl. The initial results of this study by Alina Neunkirchner, which looks at the root cause of the development of allergies, are being presented at the European Congress of Immunology, which starts in Vienna this Sunday (6 - 9 September 2015, Austria Center Vienna).

3 Sep 2015

Cells expressing faulty CFTR channel to TNF-α can 'fix' cystic fibrosis cells

Scientific experiments examining what happens to the faulty channel protein that causes cystic fibrosis during inflammation have yielded unexpected and exciting results. The study, conducted by Sara Bitam and her colleagues at INSERM in France, has just passed peer review on open science publishing platform F1000Research.

3 Sep 2015

Preserving natural structure of dietary fibre during food production can help lower blood sugar levels

A new study led by scientists at King's College London shows that preserving the natural structure of dietary fibre during food production can help to slow the rise in blood sugar levels after a meal.

3 Sep 2015

Scientists identify new mechanism for severe early infant epilepsy

Scientists at Karolinska Institutet and Karolinska University Hospital in Sweden have discovered a new explanation for severe early infant epilepsy. Mutations in the gene encoding the protein KCC2 can cause the disease, hereby confirming an earlier theory.

3 Sep 2015

Scientists map genes responsible for early embryonic development in humans

An international team of scientists led from Sweden's Karolinska Institutet has for the first time mapped all the genes that are activated in the first few days of a fertilized human egg. The study, which is being published in the journal Nature Communications, provides an in-depth understanding of early embryonic development in human - and scientists now hope that the results will help finding for example new therapies against infertility.

3 Sep 2015

Research findings may help explain why drug treatments for addiction, depression are not always effective

New research may help explain why drug treatments for addiction and depression don't work for some patients. The conditions are linked to reward and aversion responses in the brain. Working in mice, researchers at Washington University School of Medicine in St. Louis have discovered brain pathways linked to reward and aversion behaviors are in such close proximity that they unintentionally could be activated at the same time.

3 Sep 2015

Diabetes may be linked to buildup of brain tangles associated with Alzheimer’s disease

Diabetes may be linked to the buildup of tangles or tau in the brain, separate from Alzheimer's disease, according to a new study published in the September 2, 2015, online version of Neurology, the medical journal of the American Academy of Neurology.

3 Sep 2015

Novel approach to reduce 'bad' lipids in blood circulation

Xian-Cheng Jiang, PhD, professor of cell biology at SUNY Downstate Medical Center, has led a study identifying a new approach for lowering "bad" lipids in blood circulation, a critical means to combat devastating cardiovascular diseases such as atherosclerosis. The research was published in the online edition of Gastroenterology.

3 Sep 2015

Study reveals new epigenetic mechanism underlying progression of cancer tumors

Aggressive cancer growth and alterations in gene activity without changes in DNA sequence (epigenetics) are associated with mutant p53 proteins, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

3 Sep 2015

Reducing SSB intake among children and adolescents associated with greater increase in HDL-C

In the first study to investigate blood lipid levels in association with consumption of sugar-sweetened beverages (SSBs) in a racially and ethnically diverse sample of Boston area schoolchildren, researchers found there was an inverse association between SSB intake changes and HDL-cholesterol increases (HDL-C is the "good cholesterol").

3 Sep 2015

ISU researcher examines how supplements, resistance training improve muscle strength in older adults

The loss of muscle strength and function, what's known as sarcopenia, is a natural part of aging. It's also a growing public health concern because of the risk for falls, injury and decline in quality of life. That's why an Iowa State University researcher is working to slow or reverse the progression of sarcopenia.

3 Sep 2015

Researchers create method to watch activity of motor neurons in real time

When you're taking a walk around the block, your body is mostly on autopilot--you don't have to consciously think about alternating which leg you step with or which muscles it takes to lift a foot and put it back down. That's thanks to a set of cells in your spinal cord that help translate messages between your brain and your motor neurons, which control muscles.

3 Sep 2015

University of Basel scientists identify genes that play central role in development of Alzheimer's disease

Genes are not only important for regular memory performance, but also for the development of Alzheimer's disease. Researchers at the University of Basel now identified a specific group of genes that plays a central role in both processes. This group of molecules controls the concentration of calcium ions inside the cell.

3 Sep 2015

Medical Science News

Mitochondrial Pyruvate Carrier could potentially be a new drug target to treat diabetes

First ever SNP array optimized for Japanese population

Valerion announces positive results from non-clinical pilot study of VAL-1221 for treatment of Pompe disease

Regulatory T cells may reduce susceptibility to allergies

Cells expressing faulty CFTR channel to TNF-α can 'fix' cystic fibrosis cells

Preserving natural structure of dietary fibre during food production can help lower blood sugar levels

Scientists identify new mechanism for severe early infant epilepsy

Scientists map genes responsible for early embryonic development in humans

Research findings may help explain why drug treatments for addiction, depression are not always effective

Diabetes may be linked to buildup of brain tangles associated with Alzheimer’s disease

Novel approach to reduce 'bad' lipids in blood circulation

Study reveals new epigenetic mechanism underlying progression of cancer tumors

Reducing SSB intake among children and adolescents associated with greater increase in HDL-C

ISU researcher examines how supplements, resistance training improve muscle strength in older adults

Researchers create method to watch activity of motor neurons in real time

University of Basel scientists identify genes that play central role in development of Alzheimer's disease

Scientists pinpoint neurons responsible for alcohol consumption

TMIGD1 protein could be a novel target for restoring kidney function from kidney disease

New study suggests potential use of targeted therapies for two subtypes of esophageal cancer

Researchers develop new method that can target drug delivery to the lung

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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