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MACC1 gene can help predict better treatment options for patients with Klatskin carcinoma

Bile duct cancer is rare and is usually detected too late. Often only extensive liver surgery can help or, in rare cases, liver transplantation. But which patients will benefit from surgery and which will not, because their risk of cancer recurrence is too high? With the oncogene MACC1 as a biomarker, physicians for the first time have a tool to decide which treatment option is best for patients with Klatskin carcinoma, one type of bile duct cancer.

1 Sep 2015

Multiple HIV-1 variants at the beginning of infection impact viral load setpoints

HIV-1 infection with multiple founder variants points to poorer clinical outcomes than infection with a single variant, according to a paper published today in the journal Nature Medicine.

1 Sep 2015

CUMC vision researchers discover gene that causes myopia

Vision researchers at Columbia University Medical Center have discovered a gene that causes myopia, but only in people who spend a lot of time in childhood reading or doing other "nearwork."

1 Sep 2015

Gene linked to sudden cardiac death in general population identified using ICD monitoring

A gene associated with sudden cardiac death in the general population has been identified using implantable cardioverter defibrillator (ICD) monitoring in research presented for the first time at ESC Congress today.

1 Sep 2015

Gene ZSCAN4 may help treat Down syndrome

For people with Down syndrome, news from Elixirgen, LLC may brighten their day. The biotechnology company, located in the Science + Technology Park at Johns Hopkins, has outlined one of the best potential therapies yet for people with Down syndrome and other chromosome disorders in a paper entitled, "Correction of Down syndrome and Edwards syndrome aneuploidies in human cell cultures," published in the journal DNA Research.

31 Aug 2015

Regen BioPharma develops novel means of delivering RGBP-248 gene silencing nucleic acid to liver tumors

Regen BioPharma, Inc. announced today development of a novel means of delivering its patented (US Patent 8,263,571) gene silencing nucleic acid, RGBP-248, to liver tumors utilizing a clinically approved formulation as delivery system. The product in development overcomes previous hurdles with gene silencing therapeutics in which the gene silencing drug had to be delivered throughout the whole body.

31 Aug 2015

Scientists identify new protein that regulates severity of tissue damage caused by RA

Scientists have identified a new protein (C5orf30) which regulates the severity of tissue damage caused by rheumatoid arthritis (RA), an autoimmune disease that causes inflammation, pain, stiffness and damage to the joints of the feet, hips, knees, and hands.

31 Aug 2015

Study shows food craving may be hard-wired into the brain of overweight patients

An international group of researchers have found that food craving activates different brain networks between obese and normal weight patients.

31 Aug 2015

Chapman University study provides complete analysis of skill development in traditional society

Chapman University's research on aging and skill development appears as the lead article in the latest issue of American Journal of Physical Anthropology. The study, called "Skill Ontogeny Among Tsimane Forager-Horticulturalists," provides the most complete analysis to date of skill development in a traditional society.

29 Aug 2015

Synthetic tissue environment enables spatial definition of cancer cells and macrophages

Tumors are notoriously difficult to study in their natural habitat - body tissues - but a new synthetic tissue environment may give cancer researchers the next-best look at tumor growth and behavior.

29 Aug 2015

ESC Guidelines recommend DNA analysis for post mortem assessment in young sudden death victims

ESC Guidelines published today recommend DNA analysis as a fundamental component of post mortem assessment in young sudden death victims. Identification of a genetic cause helps to quickly diagnose and protect relatives.

29 Aug 2015

Biocompatible scaffold enables beating heart cells to snap together like Velcro

Engineers at the University of Toronto just made assembling functional heart tissue as easy as fastening your shoes. The team has created a biocompatible scaffold that allows sheets of beating heart cells to snap together just like Velcro™.

29 Aug 2015

Novel chemical virus can cross double lipid layer surrounding cells to release drugs

Viruses are able to redirect the functioning of cells in order to infect them. Inspired by their mode of action, scientists from the CNRS and Université de Strasbourg have designed a "chemical virus" that can cross the double lipid layer that surrounds cells, and then disintegrate in the intracellular medium in order to release active compounds.

29 Aug 2015

Oysters play important role in persistence and transmission of norovirus

Oysters not only transmit human norovirus; they also serve as a major reservoir for these pathogens, according to research published August 28 in Applied and Environmental Microbiology, a journal of the American Society for Microbiology. "More than 80 percent of human norovirus genotypes were detected in oyster samples or oyster-related outbreaks," said corresponding author Yongjie Wang, PhD.

29 Aug 2015

Keratin 17 protein plays crucial role in degrading key tumor suppressor protein

Keratin 17 (K17), a protein previously believed to provide only mechanical support for cancer cells, appears to play a crucial role in degrading a key tumor suppressor protein in cancer cells named p27. This finding, published in the September 1 issue of Cancer Research, is based on the work of researchers in the Department of Pathology at Stony Brook University School of Medicine.

29 Aug 2015

People with BPD traits have lowered activity in brain regions that support empathy

Those with borderline personality disorder, or BPD, a mental illness marked by unstable moods, often experience trouble maintaining interpersonal relationships. New research from the University of Georgia indicates that this may have to do with lowered brain activity in regions important for empathy in individuals with borderline personality traits.

29 Aug 2015

Fetal microchimerism could be a subtle and dizzyingly complex puzzle

Parents go to great lengths to ensure the health and well-being of their developing offspring. The favor, however, may not always be returned.

29 Aug 2015

Moffitt researchers hope to improve pancreatic cancer survival rates by developing blood test to identify IPMNs

Pancreatic cancer is the fourth most common cause of cancer-related death in the United States and has a 5-year survival rate of only 6 percent, which is the lowest rate of all types of cancer according to the American Cancer Society.

29 Aug 2015

KAIST scientists predict how biological circuits sustain rhythms

Our bodies have a variety of biological clocks that follow rhythms or oscillations with periods ranging from seconds to days. For example, our hearts beat every second, and cells divide periodically. The circadian clock located in the hypothalamus generates twenty-four hour rhythms, timing our sleep and hormone release.

29 Aug 2015

New non-invasive image processing technique may improve IVF success rates

A collaboration between biologists and engineers at Monash University has led to the development of a new non-invasive image processing technique to visualise embryo formation. Researchers were able to see, for the first time, the movement of all of the cells in living mammalian embryos as they develop under the microscope.

29 Aug 2015

Medical Science News

MACC1 gene can help predict better treatment options for patients with Klatskin carcinoma

Multiple HIV-1 variants at the beginning of infection impact viral load setpoints

CUMC vision researchers discover gene that causes myopia

Gene linked to sudden cardiac death in general population identified using ICD monitoring

Gene ZSCAN4 may help treat Down syndrome

Regen BioPharma develops novel means of delivering RGBP-248 gene silencing nucleic acid to liver tumors

Scientists identify new protein that regulates severity of tissue damage caused by RA

Study shows food craving may be hard-wired into the brain of overweight patients

Chapman University study provides complete analysis of skill development in traditional society

Synthetic tissue environment enables spatial definition of cancer cells and macrophages

ESC Guidelines recommend DNA analysis for post mortem assessment in young sudden death victims

Biocompatible scaffold enables beating heart cells to snap together like Velcro

Novel chemical virus can cross double lipid layer surrounding cells to release drugs

Oysters play important role in persistence and transmission of norovirus

Keratin 17 protein plays crucial role in degrading key tumor suppressor protein

People with BPD traits have lowered activity in brain regions that support empathy

Fetal microchimerism could be a subtle and dizzyingly complex puzzle

Moffitt researchers hope to improve pancreatic cancer survival rates by developing blood test to identify IPMNs

KAIST scientists predict how biological circuits sustain rhythms

New non-invasive image processing technique may improve IVF success rates

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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