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Researchers reveal mechanisms of periodic paralysis in people with rare genetic disorder

A rare genetic disorder in which people are suddenly overcome with profound muscle weakness is caused by a hole in a membrane protein that allows sodium ions to leak across cell membranes, researchers at the University of Washington School of Medicine in Seattle have found.

21 May 2018

Researchers create tool to determine patient's response to immunotherapy drugs

Understanding that not all bladder cancers are the same, researchers at the University of North Carolina Lineberger Comprehensive Cancer Center have created a tool that may help them to uncover why only a fraction of patients respond to new immune-based treatments.

21 May 2018

Researchers discover new disease mechanism in chronic tobacco smokers

Research published in the journal Clinical Science suggests that an immune signaling protein called interleukin-26 is increased among chronic smokers with lung disease and this involvement reveals disease mechanisms of interest for developing more effective therapy for these hard-to-treat patients.

21 May 2018

Reducing exposure to hormone interfering chemicals may mitigate obesity risk

Everyday products carry environmental chemicals that may be making us fat by interfering with our hormones, according to research presented in Barcelona at the European Society of Endocrinology annual meeting, ECE 2018.

21 May 2018

Higher belly fat levels linked to greater risk of vitamin D deficiency

Higher levels of belly fat are associated with lower vitamin D levels in obese individuals, according to data presented in Barcelona at the European Society of Endocrinology annual meeting, ECE 2018.

21 May 2018

New technique allows researchers to control heart cells growing in a dish

Researchers at University of California San Diego School of Medicine and their collaborators have developed a technique that allows them to speed up or slow down human heart cells growing in a dish on command - simply by shining a light on them and varying its intensity.

21 May 2018

HCM mutation prevents the heart from increasing pumping force, study shows

Researchers from Washington State University have discovered how a genetic mutation linked to hypertrophic cardiomyopathy (HCM) disrupts the heart's normal function.

21 May 2018

Researchers use MR spectroscopy to investigate mechanisms behind targeted treatment for gliomas

Using a novel imaging method, a Massachusetts General Hospital research team is investigating the mechanisms behind a potential targeted treatment for a subtype of the deadly brains tumors called gliomas.

21 May 2018

Frontal cortical lesions moderate response to prism adaptation treatment after stroke

Stroke researchers have confirmed that the presence of frontal cortical lesions moderated response to prism adaptation treatment after right-brain stroke.

21 May 2018

3D simulation reveals beneficial impact of medically induced brain cooling

Fresh insight into how the brain responds to medically induced cooling could inform treatments for head injuries and conditions such as stroke.

18 May 2018

Natural antioxidant bilirubin may provide cardiovascular benefits

Bilirubin, a yellow-orange pigment, is formed after the breakdown of red blood cells and is eliminated by the liver. It's not only a sign of a bruise, it may provide cardiovascular benefits, according to a large-scale epidemiology study.

18 May 2018

Novel IR imaging offers rapid and reliable analysis of cancer tissues

Researchers at Ruhr-Universität Bochum have deployed a novel infrared (IR) microscope with quantum cascade lasers in order to analyze tissue samples taken during routine clinical procedures for colorectal cancer diagnosis.

From Daylight Solutions Inc 18 May 2018

Gene therapy that reverses blindness in dogs could also help treat humans

A Michigan State University veterinary ophthalmologist has modified a gene therapy that reverses blindness in dogs that have a certain form of a disease known as progressive retinal atrophy, or PRA, and is now looking to advance the treatment for human use.

18 May 2018

Scientists identify new potential target to combat acute myeloid leukemia

AML is not a single disease. It is a group of leukemias that develop in the bone marrow from progenitors of specialized blood cells, the so-called myeloid cells. Rapidly growing and dividing, these aberrant cells crowd the bone marrow and bloodstream, which can be fatal within weeks or months if the disease is left untreated.

18 May 2018