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Study identifies brain circuit that balances hunger-driven and pleasure-driven eating

People eat either because they are hungry or for pleasure, even in the absence of hunger. While hunger-driven eating is fundamental for survival, pleasure-driven feeding may accelerate the onset of obesity and associated metabolic disorders.

9 Aug 2024

Rare but real: The neurological risks associated with vaccines

Review highlights the rare neurological risks associated with vaccination, emphasizing the importance of accurate detection and management strategies, particularly in the context of the COVID-19 pandemic.

9 Aug 2024

Calorie reduction doesn't hinder exercise in mice, new research finds

A new UC Riverside study demonstrates that calorie restriction doesn't deter mice from exercising, challenging the belief that dieting drains workout energy.

9 Aug 2024

Discovery of progenitor exhausted T cells offers hope for cancer patients

Tumor immunotherapy leverages the body's immune system to target and eradicate cancer cells, offering a crucial treatment for patients unresponsive to surgery or conventional therapies. Despite its potential, the effectiveness of immunotherapy is often hindered by T cell exhaustion within the tumor microenvironment, leading to diminished immune response and tumor progression. Based on these challenges, exploring the role of progenitor exhausted T cells (Tpex) in overcoming immune resistance is essential for advancing immunotherapeutic strategies and improving clinical outcomes.

8 Aug 2024

Houston Methodist pioneers new technique for targeted drug delivery to the brain

Houston Methodist researchers have discovered a more accurate and timely way to deliver life-saving drug therapies to the brain, laying the groundwork for more effective treatment of brain tumors and other neurological diseases.

8 Aug 2024

New insights into topoisomerase I inhibition reveal potential pathways for cancer therapies

A research group at the University of Bologna has identified, for the first time, the specific location and genomic context where DNA breaks occur due to the inhibition of the topoisomerase I, a protein crucial for many biological processes in cells.

8 Aug 2024

Study reveals the Mediterranean diet's role in lowering perceived stress

Following the Mediterranean diet versus the traditional Western diet might make you feel like you're under less stress, according to new research conducted by a team from Binghamton University, State University of New York.

8 Aug 2024

Bran-enriched corn flour lowers LDL cholesterol in adults with elevated levels, study finds

Study found that bran-enriched corn flour significantly reduces LDL cholesterol levels in adults with elevated cholesterol, while having minimal impact on gut microbiota composition.

8 Aug 2024

Breakthrough discovery could boost stem-cell transplants by improving cell mobilization

A discovery by a three-member Albert Einstein College of Medicine research team may boost the effectiveness of stem-cell transplants, commonly used for patients with cancer, blood disorders, or autoimmune diseases caused by defective stem cells, which produce all the body's different blood cells.

8 Aug 2024

Gene activity can predict severe side effects from melanoma treatment

An activity pattern in certain genes responsible for building proteins known as spleen tyrosine kinases can predict which melanoma patients are likely to have severe side effects from immunotherapy designed to treat the most deadly skin cancer, a new study shows.

8 Aug 2024

Zebrafish model reveals how BCG vaccine triggers immune response in bladder cancer

Using zebrafish "Avatars", an animal model developed by the Cancer Development and Innate Immune Evasion lab at the Champalimaud Foundation (CF), led by Rita Fior, Mayra Martínez-López – a former PhD student at the lab now working at the Universidad de las Américas in Quito, Ecuador – and colleagues studied the initial steps of the Bacillus Calmette-Guérin (BCG) vaccine's action on bladder cancer cells.

8 Aug 2024

Review of fasting-mimicking diets in cancer treatment

Researchers present the role of cyclic fasting and fasting-mimicking diets (FMD) in cancer therapy.

8 Aug 2024

A third of NHS shakes and soups diet participants achieve diabetes remission

Researchers assessed insulin-independent diabetes remission by total dietary replacement in England.

8 Aug 2024

New method advances the creation of implantable human organs

Growing functional human organs outside the body is a long-sought "holy grail" of organ transplantation medicine that remains elusive.

7 Aug 2024

Research finds synaptic strength key to maintaining memory in old age

Over the course of life, memory fades with varying degrees, robbing older people of the ability to recollect personal experiences.

7 Aug 2024

COVID-19 linked to higher diabetes risk, vaccination reduces impact

COVID-19 significantly increases the incidence of type 2 diabetes, particularly in unvaccinated individuals and those hospitalized. Vaccination and regular diabetes screening post-COVID-19 are crucial for managing long-term health impacts.

7 Aug 2024

Study reveals key brain cells help resist food temptations in favor of exercise

Hypocretin/orexin neurons (HONs) are crucial for resisting temptation and choosing exercise over highly palatable foods. This finding highlights potential targets for promoting physical activity and combating obesity.

7 Aug 2024

Novel bandage uses electric field to promote healing in chronic wounds

Researchers have developed an inexpensive bandage that uses an electric field to promote healing in chronic wounds.

7 Aug 2024

Does type 1 diabetes affect taste and flavor recognition?

Type 1 diabetes patients show reduced taste and flavor perception, affecting food preferences and quality of life. This highlights the need for further research into the sensory changes in T1D.

7 Aug 2024

Cordyceps sinensis shows promise in treating sepsis-associated acute kidney injury

Announcing a new publication for Acta Materia Medica journal. Cordyceps sinensis (CS) has been widely used as a dietary supplement or traditional medicine for the prevention, treatment, and prognostication of various diseases, because of its pleiotropic pharmacological properties.

7 Aug 2024