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Acetate and gut bacteria work together to reduce obesity in mice

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered a new way to reduce obesity.

19 May 2025

Study reveals how PAX3 protein drives melanoma growth

PAX3 is a transcription factor (proteins involved in converting DNA into RNA) that drives melanoma progression by promoting cell growth, migration and survival, while inhibiting cellular terminal differentiation, which is the final stage where a cell becomes specialized and cell division ends.

19 May 2025

MPXV virus lingers on hospital surfaces after patient stays

Researchers in the UK found that patients with clade Ib mpox can contaminate their hospital environments with monkeypox virus, including infectious particles. However, the risk of environmental transmission remains unclear and depends on cleaning practices and disease severity.

19 May 2025

Microscopic structural changes in the aging heart may reduce risk of arrhythmias

Virginia Tech researchers at the Fralin Biomedical Research Institute at VTC have discovered that microscopic structural changes in the aging heart may reduce the risk of irregular heartbeats.

19 May 2025

New evidence ties ADHD traits to lower activity and higher smoking rates

Young adults with higher ADHD symptoms are more likely to avoid physical effort, smoke, and lead sedentary lifestyles. The study highlights the complex links between ADHD, motivation, and health-related behaviours.

19 May 2025

Red blood cells drive blood vessel damage in diabetes by exporting toxic vesicles

Red blood cell-derived extracellular vesicles in type 2 diabetes are actively taken up by the endothelium, transferring the enzyme arginase-1 and triggering oxidative stress. This mechanism helps explain vascular complications in diabetes and offers new targets for therapeutic intervention.

19 May 2025

Zebrafish study reveals hidden dangers of environmental toxins from tires

Emerging contaminants from rubber tires N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPDQ)-are raising new red flags for aquatic ecosystems.

19 May 2025

Experimental drug could offer pain relief without the side effects of opioids

An experimental drug developed at Duke University School of Medicine could offer powerful pain relief without the dangerous side effects of opioids.

19 May 2025

New partnership aims to advance treatments for blood disorders and leukemia

A new frontier into advancing treatments for children and adults with bone marrow failure, leukaemia and other blood disorders will be achieved under a new partnership between Murdoch Children's Research Institute (MCRI) and US biotechnology company Retro Biosciences.

19 May 2025

Targeting cGAS shows promise for treating cardiac dysfunction after cardiac arrest

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Cardiac dysfunction is a prevalent and serious complication after cardiac arrest (CA), yet limited therapeutic interventions are available.

19 May 2025

Evolution of malaria protein family offers new drug targets

Researchers from the Francis Crick Institute and the Gulbenkian Institute for Molecular Medicine (GIMM) have shown that the evolution of a family of exported proteins in the malaria-causing parasite Plasmodium falciparum enabled it to infect humans.

19 May 2025

City size reduces obesity and impulsivity through better lifestyle and education

Researchers analyzing data from 915 U.S. cities found that both obesity and impulsivity (measured by ADHD rates) are less common in larger cities, with physical inactivity linking ADHD to obesity. Education and mental healthcare access further influence these patterns, highlighting modifiable factors for urban health.

18 May 2025

Electromagnetic waves disrupt SARS-CoV-2 spike protein and lower infectivity

Researchers demonstrated that specific electromagnetic wave frequencies can disrupt the SARS-CoV-2 Spike protein structure in virus-like particles, leading to reduced infectivity in cell models. This proof-of-concept study suggests new avenues for non-chemical viral inactivation methods.

18 May 2025

Preference for sweetness drives snack choices and diet quality, study reveals

Researchers explore how sweetness preference and eating behaviors interact with diet quality and added sugar intake.

18 May 2025

Single gene found to play a big role in how the liver stores energy

A new study published in Science Advances reveals that a single gene plays a big role in how the liver stores energy, a process that's critical for overall health and for managing diseases like type 2 diabetes.

16 May 2025

Study reveals how acetaminophen may actually relieve pain

A new study from Indiana University scientists may aid the pharmaceutical industry in better understanding a popular over-the-counter pain reliever: Tylenol.

16 May 2025

Cardiac 'digital twins' provide clues to more personalized heart treatments

For the first time, researchers from King's College London, Imperial College London and The Alan Turing Institute, have created over 3,800 anatomically accurate digital hearts to investigate how age, sex and lifestyle factors influence heart disease and electrical function.

16 May 2025

Research identifies seven genes that drive hematopoietic stem cell fate

Stem cells can produce any other cell type, it is just a matter of telling them in the right way. From a biological perspective, this means activating the proper genetic programme by pressing the right keys, this is, the right genes, at the right moment.

16 May 2025

Liquid biopsy advances precision medicine in gynecological cancers

A landmark review, now published in the Journal of Experimental & Clinical Cancer Research, offers a sweeping and authoritative synthesis on the use of liquid biopsy in gynecological oncology placing this emerging tool at the forefront of precision medicine for women.

16 May 2025

Targeting PME-1 may offer new strategies for treating neurological disorders and cancer

PME-1 is a protein that modifies other proteins by removing methyl groups, but high levels of PME-1 are observed in some diseases, including Alzheimer's disease (AD) and cancer.

16 May 2025