Cardiovascular Disease News and Research

Latest Cardiovascular Disease News and Research

$New hypothesis links internal fat biology to heart failure with preserved ejection fraction$

New hypothesis links internal fat biology to heart failure with preserved ejection fraction

Heart failure with preserved ejection fraction (HFpEF) appears to develop as a result of changes in the biology of a person's internal fat tissue, according to the Adipokine Hypothesis, a new way of understanding how fat may impact the heart.

1 Sep 2025

Triglyceride levels substantially reduced with olezarsen compared to placebo

Olezarsen decreased levels of triglycerides compared with placebo in patients with moderate hypertriglyceridemia and elevated cardiovascular risk, according to a late-breaking trial presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

1 Sep 2025

Baxdrostat demonstrates strong blood pressure control with favorable safety profile in phase III trial

Baxdrostat 1 mg or 2 mg once daily led to statistically significant reductions in blood pressure compared with placebo at 12 weeks in patients with uncontrolled or treatment-resistant hypertension, according to a late-breaking trial presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

Phase II trial finds zilebesiran lowers systolic blood pressure in patients with uncontrolled hypertension

Among individuals with cardiovascular disease or high cardiovascular risk and uncontrolled hypertension on multiple anti-hypertensive agents, a single subcutaneous dose of zilebesiran 300 mg led to a 5-mmHg reduction in systolic blood pressure at Month 3 compared with placebo, a difference that did not reach statistical significance.

1 Sep 2025

Extended apixaban therapy lowers recurrent VTE in patients with provoked events and enduring risk factors

Apixaban 2.5 mg twice daily significantly reduced symptomatic venous thromboembolism (VTE) recurrence, with a low risk of major bleeding, in patients with provoked VTE and enduring risk factors, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

1 Sep 2025

Inclisiran helps more high-risk patients reach LDL cholesterol goals compared to standard therapy

More patients with hypercholesterolemia at high/very high risk of cardiovascular (CV) events achieved low-density lipoprotein cholesterol (LDL-C) goals with inclisiran compared with placebo, when given on top of individually optimized lipid-lowering therapy, according to a late-breaking trial presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

Ultra-processed foods affect sperm quality and metabolism even without extra calories

A controlled crossover trial in Cell Metabolism found that ultra-processed foods increase weight, fat mass, LDL:HDL cholesterol, and alter reproductive hormones in men, with some effects independent of calorie load. These diets also showed trends toward reduced sperm motility, shifts in pollutants, and transient inflammatory responses, highlighting risks beyond excess calories.

31 Aug 2025

First ESC statement on mental health and heart disease promotes integrated care

A new ESC Clinical Consensus Statement is calling for greater awareness of the multidirectional relationship between mental health conditions and cardiovascular disease to improve patient health.

30 Aug 2025

ESC releases new guidance on lipid management to reduce cardiovascular risk

New ESC/EAS Focused Update to Guidelines, about how best to manage lipid levels in patients to reduce cardiovascular risk, recommends the use of new cardiovascular risk predication algorithms. The update was published today at ESC Congress 2025.

30 Aug 2025

New ESC guidelines prioritize women's autonomy in high-risk pregnancies

Updated ESC Guidelines, published today at ESC Congress 2025, put a focus on a woman's autonomy in making her own reproductive choices by promoting a transparent dialogue and shared decision-making for pregnancies that are high-risk for an adverse maternal and/or fetal event.

30 Aug 2025

REBOOT trial finds no benefit of beta blockers after uncomplicated heart attacks

Beta blockers-drugs commonly prescribed for a range of cardiac conditions, including heart attacks-provide no clinical benefit for patients who have had an uncomplicated myocardial infarction with preserved heart function.

30 Aug 2025

Daily use of low-dose colchicine may slow growth of blood mutations linked to disease

Taking low-dose colchicine daily may slow the progression of a common acquired gene mutation found in the blood of older adults that can lead to certain blood cancers and increased risk of cardiovascular disease, according to a subanalysis of the LoDoCo2 trial published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at ESC Congress 2025.

29 Aug 2025

Most autistic adults over 40 in the UK remain undiagnosed

89 to 97 per cent of autistic adults aged 40+ years are undiagnosed in the UK, according to the largest review of its kind which was conducted at the Institute of Psychiatry, Psychology & Neuroscience at King's College London.

29 Aug 2025

PREVENT equations provide more accurate risk estimates and support personalized hypertension care

Using the Predicting Risk of cardiovascular disease EVENTs (PREVENT™) equations provides more accurate risk estimates and supports personalized treatment for adults with high blood pressure or hypertension, according to a new scientific statement published today in the American Heart Association's peer-reviewed journals Circulation and Hypertension, and in JACC, the flagship journal of the American College of Cardiology.

28 Aug 2025

Cardiovascular outcomes worsen in patients with mental health conditions

Every 34 seconds, someone in the United States dies from heart disease. As nearly half of the country suffers from some form of cardiovascular disease (CVD), another 1 in 4 adults experience a mental health disorder in their lifetime, signaling an inevitable overlap.

28 Aug 2025

Metabolic health plays larger role than weight gain in pregnancy outcomes

Metabolic health before and during pregnancy may have a bigger influence on risks for mother and baby than simply controlling weight gain.

28 Aug 2025

High protein diet linked to increased risk of cancer-associated venous thromboembolism

Next to cancer recurrence or progression, cardiovascular diseases are the leading causes of death in cancer survivors.

28 Aug 2025

Native Hawaiian and Pacific Islander people face highest stroke rates in the U.S.

A new study found that Native Hawaiian or Pacific Islander people had the highest rate of stroke among people from other race and ethnic groups, with a rate more than three times higher than that of white people.

28 Aug 2025

Healthy diet and physical activity reduce risk of alcohol-related liver-specific mortality

A novel study investigating how physical activity and diet quality interact with different levels and patterns of alcohol consumption shows that healthy eating and increased levels of physical activity significantly lower the risk of alcohol-attributable liver-related mortality.

27 Aug 2025

Eating more animal protein may slightly lower cancer mortality

Investigating protein intake, the study shows no mortality risk from animal or plant sources, with animal protein linked to modest cancer protection.

27 Aug 2025

Cardiovascular Disease News and Research

Latest Cardiovascular Disease News and Research

New hypothesis links internal fat biology to heart failure with preserved ejection fraction

Triglyceride levels substantially reduced with olezarsen compared to placebo

Baxdrostat demonstrates strong blood pressure control with favorable safety profile in phase III trial

Phase II trial finds zilebesiran lowers systolic blood pressure in patients with uncontrolled hypertension

Extended apixaban therapy lowers recurrent VTE in patients with provoked events and enduring risk factors

Inclisiran helps more high-risk patients reach LDL cholesterol goals compared to standard therapy

Ultra-processed foods affect sperm quality and metabolism even without extra calories

First ESC statement on mental health and heart disease promotes integrated care

ESC releases new guidance on lipid management to reduce cardiovascular risk

New ESC guidelines prioritize women's autonomy in high-risk pregnancies

REBOOT trial finds no benefit of beta blockers after uncomplicated heart attacks

Daily use of low-dose colchicine may slow growth of blood mutations linked to disease

Most autistic adults over 40 in the UK remain undiagnosed

PREVENT equations provide more accurate risk estimates and support personalized hypertension care

Cardiovascular outcomes worsen in patients with mental health conditions

Metabolic health plays larger role than weight gain in pregnancy outcomes

High protein diet linked to increased risk of cancer-associated venous thromboembolism

Native Hawaiian and Pacific Islander people face highest stroke rates in the U.S.

Healthy diet and physical activity reduce risk of alcohol-related liver-specific mortality

Eating more animal protein may slightly lower cancer mortality

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Cardiovascular Disease News and Research

Latest Cardiovascular Disease News and Research

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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