Cardiovascular Disease News and Research

Latest Cardiovascular Disease News and Research

Large doses of vitamin C may moderately reduce blood pressure

Taking large doses of vitamin C may moderately reduce blood pressure, according to an analysis of years of research by Johns Hopkins scientists. But the researchers stopped short of suggesting people load up on supplements.

21 Apr 2012

Positive results from Alnylam’s ALN-PCS Phase I trial on severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today positive results from its Phase I clinical trial of ALN-PCS, an RNAi therapeutic targeting PCSK9 for the treatment of severe hypercholesterolemia.

21 Apr 2012

National award celebrates landmark discovery in gut flora and cardiovascular disease

Stanley Hazen, M.D., Ph.D., was recently honored with an inaugural Top 10 Clinical Research Achievement Award from an organization comprised of the nation's most acclaimed academic medical centers and other groups, in recognition of Dr. Hazen's Nature article, "Gut flora dependent metabolism of dietary phosphatidylcholine contributes to cardiovascular disease."

20 Apr 2012

First study to look at link between gender and mother's cardiac disease

Women with heart disease are more likely to give birth to female rather than male babies according to a new study presented today at the World Congress of Cardiology. The study found that three-quarters of the 216 children born to 200 pregnant women with diagnosed heart disease were female.

20 Apr 2012

RHD patients seek treatment in the very late stages of disease

Patients with rheumatic heart disease (RHD) are being admitted to hospital too late to prevent the need for heart surgery, according to a new study carried out by doctors in Yemen and presented today at the World Congress of Cardiology.

20 Apr 2012

Omega-3 fatty acids inhibit detrimental effects of smoking on arterial function

Omega-3 fatty acids may help to reduce the physical harm caused by smoking, according to a new study presented today at the World Congress of Cardiology.

20 Apr 2012

NALFD patients with modest alcohol intake are half as likely to develop NASH

People with nonalcoholic fatty liver disease (NALFD) who consume alcohol in modest amounts - no more than one or two servings per day - are half as likely to develop hepatitis as non-drinkers with the same condition, reports a national team of scientists led by researchers at the University of California, San Diego School of Medicine.

20 Apr 2012

Physical activity reduces CVD mortality risk in patients with hypertension

In the study, all-cause and CVD mortality risks were found to be significantly higher among study participants that didn't exercise compared with active participants at all blood pressure levels. Moreover, the excess mortality risks of physical inactivity, when converted into a "blood pressure equivalence of physical activity" measurement, revealed that physical inactivity was similar to a rise in mortality risk equivalent to an increase in blood pressure of 40-50 mmHg.

20 Apr 2012

Optimism could benefit the heart: A review of studies

A Harvard School of Public Health review of more than 200 studies suggests that optimism is good for the heart. The researchers looked at studies that had recorded psychological well-being and cardiovascular health. This revealed that factors such as optimism, life satisfaction, and happiness appeared to be linked associated with a reduced risk of heart and circulatory diseases, regardless of a person's age, socio-economic status, smoking status or body weight. Disease risk was 50% lower among the most optimistic individuals.

19 Apr 2012

Final data from Santaris’ miravirsen Phase 2a trial on HCV to be presented at ILC 2012

Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies, will present final data from a Phase 2a trial showing that miravirsen given as a four-week monotherapy treatment provided robust dose-dependent anti-viral activity with a mean reduction of 2 to 3 logs from baseline in HCV RNA (log10 IU/mL) that was sustained well beyond the end of therapy.

19 Apr 2012

CRF announces top 10 clinical research achievement awards

Ten outstanding clinical research projects from institutions around the country have been selected to receive the inaugural Clinical Research Forum Top 10 Clinical Research Achievement Awards. The winning projects are compelling examples of the scientific innovation that results from the nation's investment in clinical research that can benefit human health and welfare.

19 Apr 2012

LVHT more common in afro-Caribbean athletes

Left-ventricular hyper-trabeculation (LVHT) - a feature of certain cardiomyopathies (chronic disease of the heart muscle) - has been found to be more common in black, male athletes according to a new study presented today at the World Congress of Cardiology.

19 Apr 2012

Testosterone may help heart failure patients: Study

The researchers used testosterone patches and injections that improved the breathing and exercise abilities of people with heart failure, a chronic inability of the heart to pump enough blood to the rest of the body. Although most of the study participants were men, the researchers said the results would likely apply to women as well, through much smaller doses of testosterone.

18 Apr 2012

Frequent but moderate consumption of alcohol before and after heart attack may improve health outcomes

The Health Professionals Follow-up Study (HPFS) is a prospective cohort study of 51,529 US male health professionals. During the follow up of these men between 1986 to 2006, published in the European Heart Journal, 1,818 men were confirmed with incident non-fatal myocardial infarction (MI) - a non fatal heart attack.

18 Apr 2012

Surgery to remove only the tumor preferable to removing entire kidney

Kidney cancer patients who had only their tumor removed had better survival than patients who had their entire kidney removed, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

18 Apr 2012

Medtronic plans IN.PACT Global drug-eluting balloon SFA clinical study

In conjunction with the Charing Cross International Symposium (CX34), which concludes today in London, Minneapolis-based Medtronic, Inc. announced its plans for the imminent start of the IN.PACT Global SFA clinical study, an international research program to evaluate the treatment of peripheral artery disease using the company's IN.PACT Admiral drug-eluting balloon.

From Medtronic 18 Apr 2012

Hidden sugar in “healthy” fruit drinks often underestimated

The Glasgow University study asked more than 2,000 people in the UK to estimate how much sugar was in a range of drinks. While many overestimated the amount in fizzy beverages, they underestimated levels in ‘smoothies’ and fruit juices. The research also found soft drinks could be accounting for a large chunk of their recommended calorie intake.

17 Apr 2012

Novel system for 3D reconstruction and examination of tissues at microscopic resolution

Researchers have developed a novel, easy-to-use system for three-dimensional (3D) reconstruction and examination of tissues at microscopic resolution, with the potential to significantly enhance the study of normal and disease processes, particularly those involving structural changes. The new approach, using conventional histopathological methods, is described in the May issue of The American Journal of Pathology.

17 Apr 2012

UCSF scientists assemble high-value genetic resource to help researchers

One of the ultimate ways of understanding what impact any particular gene has in human health or disease is to disrupt it-knocking it down or wiping it out in a worm, fly or mouse and gauging what happens next. Now scientists at the University of California, San Francisco (UCSF) Diabetes Center and the Gladstone Institute for Cardiovascular Disease have assembled a large publicly available resource to help researchers determine the importance of genes in mice and better gauge what roles they might play in disease.

17 Apr 2012

High-fibre diet protects women from cardiovascular disease

Foods high in fibre provide good protection against cardiovascular disease, and the effect is particularly marked in women. This is shown in a new study from Lund University in Sweden.

17 Apr 2012