Cardiovascular Disease News and Research

Latest Cardiovascular Disease News and Research

Blocking Hutchinson-Gilford progeria syndrome (HGPS) with anticancer drugs

A class of anticancer drugs currently being evaluated in phase 3 clinical trials may also be an effective treatment for Hutchinson-Gilford progeria syndrome (HGPS), a fatal genetic disorder that causes premature aging.

29 Aug 2005

Drugs known as farnesyltransferase inhibitors (FTIs) may hold promise for premature aging disorder

In a surprising development, a research team led by the National Human Genome Research Institute (NHGRI), has found that a class of experimental anti-cancer drugs also shows promise in laboratory studies for treating a fatal genetic disorder that causes premature aging.

29 Aug 2005

New understanding of role cholesterol plays in causing heart attacks, strokes

Research by a Michigan State University cardiologist published in the September edition of Clinical Cardiology has shed new light on the role that cholesterol plays in causing heart attacks, strokes and other cardiovascular events in humans.

29 Aug 2005

UCI study helps identify one reason why women have lower stroke risk than men

Estrogen's role as an inhibitor of toxic-free radicals in cerebral blood vessels may be a key reason why premenopausal women have a lower stroke risk than men.

26 Aug 2005

Call for closer examination of a metabolic syndrome

Two major health organizations in Europe and the United States are calling for closer examination of a syndrome that has been widely believed to predict the risk of developing heart disease, questioning whether it has been appropriately defined and whether it is in fact a syndrome at all.

25 Aug 2005

Experimental immunusuppressant drug preserves transplanted kidneys

An international team of transplant physicians has shown that the investigational drug belatacept (LEA29Y) preserves transplanted kidney function as effectively as cyclosporine, the drug most commonly used to prevent the immune system from rejecting transplanted organs.

24 Aug 2005

New drug that selectively blocks immune responses protects kidneys after transplant

In an international clinical trial, a new drug that selectively blocks immune responses has proved as effective in preventing acute kidney transplant rejection as cyclosporine, the standard anti-rejection treatment.

24 Aug 2005

Taking aspirin longterm could reduce colorectal cancer risk

According to new report from the Nurses' Health Study (NHS), regular, long-term aspirin use can significantly reduce the risk of colorectal cancer.

24 Aug 2005

No major difference in the incidence of dementia between men and women

A new study on the incidence of dementia in England and Wales, published in the forthcoming issue of the open access journal PLoS Medicine, challenges three commonly held assumptions about dementia.

23 Aug 2005

Aspirin use can significantly reduce the risk of colorectal cancer

A new report from the Nurse's Health Study finds that regular, long-term aspirin use can significantly reduce the risk of colorectal cancer, as suggested by several earlier studies.

23 Aug 2005

MRI helps map smallest deformations inside hearts

Using magnetic resonance imaging technology, or MRI, to tag the work of millions of individual strands of heart muscle fibers, researchers at Johns Hopkins have successfully mapped the smallest deformations inside the beating hearts of 441 middle-aged and elderly men and women who have either silently developed heart disease or remained healthy.

22 Aug 2005

Reasons for complications with kidney failure patients

Mayo Clinic researchers searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their attention on the use of heparin, a drug used to reduce clotting of the blood.

18 Aug 2005

Separate studies produce conflicting results on race and gender disparities in U.S. health system

Two newly released studies in the U.S. have to some extent come to conflicting results. According to one study, by researchers at Emory University, attempts over the last decade to address race and gender disparities in the treatment of U.S. patients hospitalized for heart attacks, still in some respects raise cause for concern.

18 Aug 2005

Little convincing evidence that dietary antioxidant supplements such as vitamin E prevent heart disease

Instead there has been a surprise finding, which relates to a synthetic antioxidant, the drug Probucol, which is no longer prescribed in Australia.

11 Aug 2005

Ground-breaking discoveries that provide hope of an alternative treatment option for haemophilia sufferers

Haemophilia is a hereditary blood disease, primarily affecting males, where the blood fails to clot causing potentially life-threatening 'bleeds'. About one in 6000 Australian males is born with haemophilia in severe, moderate or mild form. People with haemophilia rely on intravenous infusion of recombinant Factor VIII clotting protein.

11 Aug 2005

High insulin levels increase inflammatory markers and beta-amyloids

Moderately elevated levels of insulin increase the levels of inflammatory markers and beta-amyloid in plasma and in cerebrospinal fluid, and these markers may contribute to Alzheimer's disease, according to a new study posted online today from Archives of Neurology, one of the JAMA/Archives journals.

9 Aug 2005

Drinking in moderation boosts brainpower

In news guaranteed to prompt more than a few toasts down the pub, Aussie researchers are saying that among those who enjoy a bevy or two, moderate drinkers are better thinkers than teetotallers or those who overindulge.

4 Aug 2005

Researchers find C-reactive protein differences, a predictor of heart disease among sexes, races

A protein in the blood that is considered to be a key indicator of future heart disease may vary considerably among women and men, as well as blacks and whites, according to new research at UT Southwestern Medical Center.

2 Aug 2005

Masked hypertension poses hidden hazard

Patients with "masked" hypertension that is not detected by routine office blood pressure measurements appear to have stroke and death rates similar to that of patients with sustained high blood pressure; whereas patients with so-called "white coat" hypertension appear to have no greater risk than people with normal blood pressure, according to a new study in the Aug. 2, 2005, issue of the Journal of the American College of Cardiology.

2 Aug 2005

Study finds risk of death increases with peritoneal dialysis over hemodialysis

Researchers at Johns Hopkins have found that in people with end-stage kidney disease (ESRD), choosing peritoneal dialysis over hemodialysis increases their risk of dying by 50 percent.

2 Aug 2005