Chromosome News and Research

Latest Chromosome News and Research

UC researchers sequence individual glioblastoma genomes and track abnormalities through the bloodstream

Medical scientists know this about glioblastoma multiforme: the malignant brain tumor is aggressive, it is elusive, and it appears in different permutations.

5 Apr 2011

Known cancer-linked gene involved in subset of advanced prostate tumors

Researchers at the University of Michigan Comprehensive Cancer Center have identified a genetic anomaly that may drive the aggressive spread of a rare subset of prostate cancers.

5 Apr 2011

Scientists reveal unknown role of cilia protein IFT88 in mitosis

Researchers at the University of Massachusetts Medical School have described a previously unknown role for the cilia protein IFT88 in mitosis, the process by which a dividing cell separates its chromosomes containing the cell's DNA into two identical sets of new daughter cells.

5 Apr 2011

Researchers identify new gene that can influence person's risk of developing epilepsy

Vanderbilt University researchers have identified a new gene that can influence a person's risk for developing epilepsy. The findings, reported in the March 29 Proceedings of the National Academy of Sciences, could improve molecular diagnostic tools and point to novel therapeutic targets for epilepsy.

5 Apr 2011

Study links chronic stress of cancer with telomere length

Results of a study presented at the AACR 102nd Annual Meeting 2011, held here April 2-6, lend credence to the idea that improving quality of life affects stress-related biological markers and possibly the health of people with cancer.

4 Apr 2011

Common genetic variation linked to bladder cancer risk and telomere length

A common genetic variation links to both bladder cancer risk and to the length of protective caps found on the ends of chromosomes, scientists at The University of Texas MD Anderson Cancer Center reported today at the AACR 102nd Annual Meeting.

4 Apr 2011

Transgenomic to present study results of high-sensitivity cancer mutation assays at AACR

Transgenomic, Inc. announced today that its scientists have completed studies employing the company's high-sensitivity cancer mutation assays using two proprietary technologies, Ice COLD-PCR and BLOCker-Sequencing. Results from these studies will be presented at the American Association for Cancer Research meeting in Orlando, Florida, April 2-6, 2011.

2 Apr 2011

DNA damage can lead to regulation of inflammatory responses

Researchers offer the first evidence that DNA damage can lead to the regulation of inflammatory responses, the body's reaction to injury. The proteins involved in the regulation help protect the body from infection.

1 Apr 2011

Glasgow Professor discusses about new approach for CML treatment at UK conference

Speaking at the UK National Stem Cell Network conference in York later today, Professor Tessa Holyoake from the University of Glasgow will discuss a brand new approach to treating chronic myeloid leukaemia in which a small number of cancer cells persist despite effective therapy thus preventing cure.

31 Mar 2011

Study links genes with alcohol consumption among Asians

In a study of 1,721 Korean male drinkers aged 40󈞱 y in an urban population-based cohort, and another sample of 1,113 male drinkers from an independent rural cohort, information on average daily alcohol consumption was collected and DNA samples were collected for genotyping.

31 Mar 2011

Low doses of estrogen, growth hormone can increase height in girls with Turner syndrome

Giving girls with Turner syndrome low doses of estrogen, as well as growth hormone, years before the onset of puberty, increases their height and offers a wealth of other benefits, say a team of researchers led by Thomas Jefferson University.

31 Mar 2011

Transgenomic discovers novel BLOCker-Sequencing technology

Transgenomic, Inc. today announced that it has discovered a novel sequencing technology, which the company has termed BLOCker-Sequencing, which enhances the limit of detection of standard Sanger Sequencing, enriches for direct sequencing of mutated DNA over wild-type and can be run on standard Sanger Sequencing equipment.

30 Mar 2011

Study: Donor's DNA level in heart transplant recipient's blood can reveal organ rejection

Heart transplant recipients and their physicians are likely more concerned with the function of the donated organ than with the donor's DNA sequences that tag along in the new, healthy tissue.

29 Mar 2011

CytRx to present bafetinib preclinical study results at AACR Annual Meeting

CytRx Corporation, a biopharmaceutical company specializing in oncology, today announced that results from a series of preclinical studies demonstrating that its oncology drug candidate bafetinib inhibits bone destruction in model systems is being presented on April 2, 2011 at the American Academy for Cancer Research 102nd Annual Meeting in Orlando, Florida.

29 Mar 2011

Genetic link to attempted suicide discovered - Findings could lead to new avenues of treatment

Johns Hopkins scientists, reporting in the journal Molecular Psychiatry, have identified a small region on chromosome 2 that is associated with increased risk for attempted suicide. This small region contains four genes, including the ACP1 gene, and the researchers found more than normal levels of the ACP1 protein in the brains of people who had committed suicide. This protein is thought to influence the same biological pathway as lithium, a medication known to reduce the rate of suicidal behavior.

28 Mar 2011

Study: Short telomeres may predispose people to age-related diabetes

New evidence has emerged from studies in mice that short telomeres or "caps" at the ends of chromosomes may predispose people to age-related diabetes, according to Johns Hopkins scientists.

25 Mar 2011

DNA "end-caps" length linked to diabetes risk: New role for short telomeres

New evidence has emerged from studies in mice that short telomeres or “caps” at the ends of chromosomes may predispose people to age-related diabetes, according to Johns Hopkins scientists.

24 Mar 2011

Resveratrol can provide resistance before and after hazardous radiation exposure

Clinical studies of Resveratrol--recognized for its proven role in activating the longevity gene to inhibit age-related diseases--have shown that its antioxidant power provides resistance before and after exposure to hazardous radiation.

24 Mar 2011

Zebrafish model of human melanoma reveals new cancer gene

Looking at the dark stripes on the tiny zebrafish you might not expect that they hold a potentially important clue for discovering a treatment for the deadly skin disease melanoma. Yet melanocytes, the same cells that are are responsible for the pigmentation of zebrafish stripes and for human skin color, are also where melanoma originates.

24 Mar 2011

New study to provide better diagnoses for children with developmental disorders

A new UK study will provide better diagnoses for children with developmental disorders caused by changes in their genetic makeup. Scientists and clinicians will build a new national resource of genetic information and symptoms, based on data from 12,000 children who have a serious delay in their physical or mental development or are born with multiple malformations.

23 Mar 2011

Chromosome News and Research

Latest Chromosome News and Research

UC researchers sequence individual glioblastoma genomes and track abnormalities through the bloodstream

Known cancer-linked gene involved in subset of advanced prostate tumors

Scientists reveal unknown role of cilia protein IFT88 in mitosis

Researchers identify new gene that can influence person's risk of developing epilepsy

Study links chronic stress of cancer with telomere length

Common genetic variation linked to bladder cancer risk and telomere length

Transgenomic to present study results of high-sensitivity cancer mutation assays at AACR

DNA damage can lead to regulation of inflammatory responses

Glasgow Professor discusses about new approach for CML treatment at UK conference

Study links genes with alcohol consumption among Asians

Low doses of estrogen, growth hormone can increase height in girls with Turner syndrome

Transgenomic discovers novel BLOCker-Sequencing technology

Study: Donor's DNA level in heart transplant recipient's blood can reveal organ rejection

CytRx to present bafetinib preclinical study results at AACR Annual Meeting

Genetic link to attempted suicide discovered - Findings could lead to new avenues of treatment

Study: Short telomeres may predispose people to age-related diabetes

DNA "end-caps" length linked to diabetes risk: New role for short telomeres

Resveratrol can provide resistance before and after hazardous radiation exposure

Zebrafish model of human melanoma reveals new cancer gene

New study to provide better diagnoses for children with developmental disorders

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Synthetic Psychedelics: A Growing Public Health Concern

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Chromosome News and Research

Latest Chromosome News and Research

Real-time Raman monitoring for pharmaceutical hot melt extrusion

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