Collagen

Collagen is a fibrous protein found in cartilage and other connective tissue.

What is Collagen?

Collagen is a protein made up of amino-acids, which are in turn built of carbon, oxygen and hydrogen. Collagen contains specific amino acids – Glycine, Proline, Hydroxyproline and Arginine.

Collagen Types and Linked Disorders

Collagen Degradation Pathways in Humans

Latest Collagen News and Research

Temple researchers reverse muscle fibrosis associated with overuse injury in animals

Overuse injuries - think muscle strains, tennis elbow, and rotator cuff tears - are a considerable problem in the United States, especially among young athletes.

30 Mar 2020

Why Primary Cells Are Important for In Vitro ADME-Tox Studies

Lonza is a large, multinational corporation serving the entire pharmaceutical product development and manufacturing pipeline, from non-clinical research products to final dosage and delivery solutions.

From Lonza 26 Mar 2020

Lab-on-chip device to monitor how extracellular matrix responds to disease

Similarly to how a picked lock gives away that someone has broken into a building, the stiffening of a structure surrounding cells in the human body can indicate that cancer is invading other tissue.

21 Mar 2020

New two-step technique to repair herniated discs

A new two-step technique to repair herniated discs uses hyaluronic acid gel to re-inflate the disc and collagen gel to seal the hole, essentially repairing ruptured discs like you'd repair a flat tire.

11 Mar 2020

Research shows how physical cues drive cell migration, cancer metastasis, and treatment

Cancer cells are a product of their environment. The surrounding cells, extracellular matrix, and other features influence disease progression and spread of cancer cells to other parts of the body.

28 Feb 2020

Omega-3 fatty acids may help prevent complications in women receiving breast implants

For women receiving breast implants during reconstructive or cosmetic breast surgery, scarring around the implant - called capsular contracture - is a common, costly, and painful complication.

26 Feb 2020

Researchers uncover how cancer cells override environmental cues to consume energy

Using human lung cancer cells, UT Southwestern researchers have uncovered how cells in general modulate their energy consumption based on their surroundings and, furthermore, how cancer cells override those cues to maximize energy use.

24 Feb 2020

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

Pancreatic cancer 'time machine' reveals tumor development and invasion

Pancreatic cancer has one of the worst survival rates among cancers. Patients can expect as low as a 9% chance to live for at least five years after being diagnosed.

18 Feb 2020

New technology enables scientists to analyze behavior of cancer cells in lab-grown tumors

New technology developed at UCL is, for the first time, enabling cancer scientists to analyze the individual behavior of millions of different cells living inside lab-grown tumors - a breakthrough which could lead to new personalised cancer treatments.

17 Feb 2020

Scientists develop new tool using machine learning to diagnose lymphedema

Scientists at the TSU Laboratory for Biophotonics, with specialists from the Tomsk Scientific Research Institute of Microsurgery, have developed a new tool for diagnosing lymphedema, a severe pathology that can develop after radical treatment of several oncological diseases.

17 Feb 2020

Cellular and molecular view of intact transparent human organs

For the first time, researchers managed to make intact human organs transparent. Using microscopic imaging they could revealed underlying complex structures of the see-through organs at the cellular level.

13 Feb 2020

Human textiles to replace damaged blood vessels

What if we could replace a patient's damaged blood vessels with brand new ones produced in a laboratory? This is the challenge set by Inserm researcher Nicolas L'Heureux, who is working on the human extracellular matrix - the structural support of human tissues that is found around practically all of the body's cells.

10 Feb 2020

Study finds link between bladder cancer and collagen receptor

A team of investigators has recently discovered that the collagen receptor DDR1 functionally interacts with the insulin-like growth factor system in regulating bladder cancer.

9 Feb 2020

Targeting a protein could be key to suppressing breast cancer metastasis

A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a protein known as heat shock protein 47 (Hsp47) could be key for suppressing breast cancer metastasis.

5 Feb 2020

Study reveals new strategies to prevent skin scarring

A new study in Burns & Trauma, published by Oxford University Press, reveals promising new strategies to prevent skin scarring after injuries.

4 Feb 2020

Researchers discover new target for repairing heart after heart attack

Billions of cardiac muscle cells are lost during a heart attack. The human heart cannot replenish these lost cells, so the default mechanism of repair is to form a cardiac scar.

30 Jan 2020

Buck study uncovers how astrocyte senescence promotes neurodegeneration

Although a link has been established between chronic inflammation and neurodegenerative diseases, there have been many open questions regarding how cellular senescence, a process whereby cells that stop dividing under stress spew out a mix of inflammatory proteins, affects these pathologies.

29 Jan 2020