Collagen

Collagen is a fibrous protein found in cartilage and other connective tissue.

What is Collagen?

Collagen is a protein made up of amino-acids, which are in turn built of carbon, oxygen and hydrogen. Collagen contains specific amino acids – Glycine, Proline, Hydroxyproline and Arginine.

Collagen Types and Linked Disorders

Collagen Degradation Pathways in Humans

Latest Collagen News and Research

Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model

Researchers from Kumamoto University have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating pathological conditions like reduced kidney function, glomerular damage, inflammation and fibrosis.

15 Apr 2021

Researchers develop innovative tough gel sheathed sutures inspired by human tendons

Sutures are used to close wounds and speed up the natural healing process, but they can also complicate matters by causing damage to soft tissues with their stiff fibers. To remedy the problem, researchers from Montreal have developed innovative tough gel sheathed (TGS) sutures inspired by the human tendon.

8 Apr 2021

New bioprinting process uses ultrashort peptides to print hydrogel scaffolds

A new automated process prints a peptide-based hydrogel scaffold containing uniformly distributed cells. The scaffolds hold their shapes well and successfully facilitate cell growth that lasts for weeks.

5 Apr 2021

Cell Migration and Invasion Assays by Platypus Technologies

Cell Migration and Invasion Assays by Platypus Technologies use exclusion zone technology to ensure consistent cell-free regions for each experiment.

From Platypus Technologies, LLC 5 Apr 2021

The Role Surface Coatings Play in Cell Migration

Experiments show that surface coatings play an important role in cell migration.

From Platypus Technologies, LLC 5 Apr 2021

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Researchers at the University of California, San Francisco, have discovered that aggressive, triple-negative breast cancers (TNBCs) can evade treatment by reorganizing and softening the collagen matrix that surrounds the cancer cells.

3 Apr 2021

Researchers develop a recombinant SARS-CoV-2 receptor-binding domain trimer vaccine candidate

New research deals with the development of RBD trimer as a potent target for SARS-CoV-2 subunit vaccines. This study revealed the development of a trimeric RBD subunit vaccine candidate that could induce strong humoral and cellular immune responses in nonhuman primates (NHPs), namely, rhesus macaques.

1 Apr 2021

Specific gene may play a causal role in heart disease independent of cholesterol levels

High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke.

1 Apr 2021

Study sheds new light on the role of oxygen deprivation in cancer development

A team of University of Colorado School of Medicine researchers recently published a paper offering new insight into the role that oxygen deprivation, or hypoxia, plays in cancer development.

1 Apr 2021

POSTECH researchers produce artificial lung model using 3D printing

The warmer temperature and blooming flowers signal the arrival of spring. However, worries about respiratory diseases are also on the rise due to fine dust and viruses.

26 Mar 2021

New study shows large within- and between-assay variation for ß-CTX measurement

A new study by the IFCC‑IOF Committee for Bone Metabolism shows large within- and between-assay variation for ß-CTX measurement; until harmonization is achieved, proposes measuring ß-CTX by the same assay on EDTA plasma, especially for research.

25 Mar 2021

A modified protein mediates development of lung fibrosis after cadmium/carbon black exposure

The triggers and causes of a severe scarring disease of the lungs -- idiopathic pulmonary fibrosis, or IPF -- remain unclear.

18 Mar 2021

Researchers explore potential role of TARM1 protein in pathogenesis of rheumatoid arthritis

TARM1 is a receptor protein whose role in the functioning of the immune system is unknown. In a new study, scientists from Japan have explored the potential role of TARM1 in the pathogenesis of rheumatoid arthritis by analyzing mouse models.

17 Mar 2021

Propylparaben exposure during pregnancy may lessen protection against breast cancer

Low doses of propylparaben - a chemical preservative found in food, drugs and cosmetics - can alter pregnancy-related changes in the breast in ways that may lessen the protection against breast cancer that pregnancy hormones normally convey, according to University of Massachusetts Amherst research.

16 Mar 2021

Study identifies three novel binding receptors for SARS-CoV-2

A team of scientists from the United Kingdom recently conducted a large-scale screening of several membrane-bound and soluble host cell receptors to identify novel binding partners for SARS-CoV-2. They have identified three novel receptors expressed on the human cell membrane; of which, one binds to SARS-CoV-2 spike with similar affinity as angiotensin-converting enzyme 2 (ACE2).

12 Mar 2021

Researchers discover new molecular target that could treat idiopathic pulmonary fibrosis

Researchers at the University of Alabama at Birmingham have identified a new molecular target that could potentially treat the deadly, aging-related lung disease idiopathic pulmonary fibrosis (IPF).

10 Mar 2021

Study describes the infection of human cells by intestinal pathogen during spaceflight

Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.

9 Mar 2021

Ultrasound elastography do not show the actual status of postoperative liver fibrosis

It is well-known that patients who undergo Fontan surgery slowly develop liver fibrosis for years post-operatively. In the past decade, these incidences have been steadily increasing and this is due partly to the need for an accurate diagnostic method.

8 Mar 2021

Study clarifies the role of collagen during pancreatic cancer development

Contrary to long-held beliefs, Type I collagen produced by cancer-associated fibroblasts may not promote cancer development but instead plays a protective role in controlling pancreatic cancer progression, reports a new study from researchers at The University of Texas MD Anderson Cancer Center.

4 Mar 2021

Comet supercomputer reveals the mechanical process of cancer growth

According to the World Health Organization, one in six worldwide deaths have been attributed to cancer; however, these fatalities were not due to initial malignant tumors-;the deaths were caused by the spread of cancer cells to surrounding tissues and subsequent tumor growth.

3 Mar 2021

Collagen

Overview

Collagen Molecular Structure

Collagen Fibrillar Structure

Collagen Synthesis

Feature Articles

Collagen Medical Uses

Collagen Uses

Collagen Types and Linked Disorders

Collagen Degradation Pathways in Humans

Latest Collagen News and Research

Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model

Researchers develop innovative tough gel sheathed sutures inspired by human tendons

New bioprinting process uses ultrashort peptides to print hydrogel scaffolds

Cell Migration and Invasion Assays by Platypus Technologies

The Role Surface Coatings Play in Cell Migration

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Researchers develop a recombinant SARS-CoV-2 receptor-binding domain trimer vaccine candidate

Specific gene may play a causal role in heart disease independent of cholesterol levels

Study sheds new light on the role of oxygen deprivation in cancer development

POSTECH researchers produce artificial lung model using 3D printing

New study shows large within- and between-assay variation for ß-CTX measurement

A modified protein mediates development of lung fibrosis after cadmium/carbon black exposure

Researchers explore potential role of TARM1 protein in pathogenesis of rheumatoid arthritis

Propylparaben exposure during pregnancy may lessen protection against breast cancer

Study identifies three novel binding receptors for SARS-CoV-2

Researchers discover new molecular target that could treat idiopathic pulmonary fibrosis

Study describes the infection of human cells by intestinal pathogen during spaceflight

Ultrasound elastography do not show the actual status of postoperative liver fibrosis

Study clarifies the role of collagen during pancreatic cancer development

Comet supercomputer reveals the mechanical process of cancer growth

Breath Analysis: How Could it Improve Healthcare and Diagnosis?

Advancing the Diagnosis and Treatment of Ovarian Cancer

World Health Day 2021 – “Building a fairer, healthier world”

Collagen

Overview

Feature Articles

Collagen Medical Uses

Collagen Uses

Collagen Types and Linked Disorders

Collagen Degradation Pathways in Humans

Latest Collagen News and Research

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