Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

ITBCC takes revolutionary step in improving biomarker assessment in colorectal cancer

In colorectal cancer, the presence of invasive tumor cells at the advancing edge of the tumor can provide valuable information on prognosis. Initiated by the Colorectal Cancer Research Group at the Institute of Pathology, University of Bern, a consensus conference was held to determine how this phenomenon should best be put into practice.

31 May 2016

Free screening colonoscopies for uninsured, high-risk CRC patients may help in early detection of cancer

For uninsured patients who are at a high risk for colorectal cancer (CRC), performing free screening colonoscopies can identify cancer at an earlier stage and appears to be cost neutral from a hospital system perspective, according to study results published online in the Journal of the American College of Surgeons ahead of print publication.

27 May 2016

Lancet study links worldwide economic crisis to increased cancer mortality

Unemployment and reduced public-sector health spending following the 2008 global economic crisis were associated with increased cancer mortality, according to a new study published in The Lancet.

27 May 2016

New hydrogel-based biochip may help in early diagnosis of bowel cancer

Researchers from the Moscow Institute of Physics and Technology, the Engelhardt Institute of Molecular Biology, the Institute of Bioorganic Chemistry and a number of other Russian research centers have developed a new method of diagnosing colorectal cancer.

27 May 2016

Study provides better understanding of sequence of genetic events in colorectal cancer premalignancy

Whole-exome sequencing of both colorectal adenomas (precancers often called polyps) and intestinal mucosa at risk for developing into adenomas from patients with familial adenomatous polyposis (FAP) has generated a comprehensive picture of the genomic alterations that characterize the evolution of normal mucosa to precancer.

25 May 2016

Mitoxantrone for MS linked to colorectal cancer risk

Treatment with mitoxantrone for multiple sclerosis carries only a mildly increased risk of malignancy overall, but the risk of colorectal cancer and leukaemia is heightened, researchers have found.

24 May 2016

Study shows endoscopist knowledge of positive Cologuard result may enhance colonoscopy quality

An endoscopist's knowledge of a positive Cologuard test improves colonoscopy performance, according to a poster presentation at last week's Digestive Disease Week conference.

24 May 2016

Researchers identify mutations that may stimulate early cancer growth in precancerous colorectal tissue

Researchers at The University of Texas MD Anderson Cancer Center have discovered mutations that may fuel early cancer growth in precancerous colorectal tissue from high-risk patients.

24 May 2016

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

The investigational anticancer therapeutic abemaciclib, which targets CDK4 and CDK6, showed durable clinical activity when given as continuous single-agent therapy to patients with a variety of cancer types, including breast cancer, non-small cell lung cancer (NSCLC), glioblastoma, and melanoma, according to results from a phase I clinical trial.

23 May 2016

Could a new test improve bowel cancer screening uptake? An interview with Professor Halloran

The most recent complete data for England (2014/15) shows an average uptake of the guaiac Faecal Occult Blood Tests (gFOBT) from those invited by the NHS Bowel Cancer Screening Programme (BCSP) of 58.22%.

23 May 2016

Diet experiments on Lynch syndrome mouse model may help in early detection of colon cancer

Colorectal cancer is the second most common cause of cancer-related deaths in the Western world, mainly because it is usually diagnosed too late. Finding ways to identify those people who are at increased risk of developing colon cancer is therefore crucial, a researcher will tell the annual conference of the European Society of Human Genetics today.

23 May 2016

Targeting ERK and compensatory pathways with drug inhibitors halts colorectal cancer growth

While investigating a potential therapeutic target for the ERK1 and 2 pathway, a widely expressed signaling molecule known to drive cancer growth in one third of patients with colorectal cancer, University of California San Diego School of Medicine researchers found that an alternative pathway immediately emerges when ERK1/2 is halted, thus allowing tumor cell proliferation to continue.

18 May 2016

New research solves mystery of why cetuximab drug proved futile for many colorectal cancer patients

Cancer researchers have identified a marker that shows up in a blood test that determines which patients with colorectal cancer that has spread would benefit from receiving the drug cetuximab.

13 May 2016

Depressed cancer patients less likely to recover well after treatment

People with depression are significantly less likely to recover well after treatment for colorectal cancer compared to those without depression, according to new research by Macmillan Cancer Support and the University of Southampton.

13 May 2016

Mitoxantrone drug users more likely to develop colorectal cancer

The multiple sclerosis (MS) drug mitoxantrone may be associated with an increased risk of colorectal cancer, according to a study published in the May 11, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology. Mitoxantrone suppresses the immune system.

12 May 2016

Medicare policy puts low-income Americans at increased risk for colorectal cancer

Colorectal cancer is the second highest cause of cancer death in the United States, expected to claim the lives of an estimated 49,190 people in 2016. The Affordable Care Act aimed to increase access to CRC screening by not holding patients responsible for all costs of the procedure, yet current Medicare insurance beneficiaries lacking supplemental insurance may not be able to afford colon cancer screening and treatment.

9 May 2016

Oophorectomy could increase colorectal cancer risk in both pre- and postmenopausal women

Colorectal cancer may rise in women who have their ovaries removed, according to new research.

5 May 2016

Bayer-new phase 3 liver cancer data

Bayer has announced that a Phase III trial evaluating its oncology compound Stivarga® (regorafenib) tablets for the treatment of patients with unresectable hepatocellular carcinoma (HCC) has met its primary endpoint of a statistically significant improvement in overall survival. The study, called RESORCE, evaluated the efficacy and safety of regorafenib in patients with HCC whose disease has progressed after treatment with sorafenib. The safety and tolerability were generally consistent with the known profile of regorafenib. Detailed efficacy and safety analyses from this study are expected to be presented at an upcoming scientific congress.

4 May 2016

ATR-FTIR spectroscopy could be effective for detecting ulcerative colitis

A minimally invasive screening for ulcerative colitis, a debilitating gastrointestinal tract disorder, using emerging infrared technology could be a rapid and cost-effective method for detecting disease that eliminates the need for biopsies and intrusive testing of the human body, according to researchers at Georgia State University.

27 Apr 2016

Cholesterol-lowering drugs may not reduce colorectal cancer risk

Long-term use of the cholesterol-lowering drugs known as statins does not appear to decrease a patient's risk of colorectal cancer, suggests a new, large case-control study from Penn Medicine researchers published this week in PLOS Medicine.

27 Apr 2016

Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

ITBCC takes revolutionary step in improving biomarker assessment in colorectal cancer

Free screening colonoscopies for uninsured, high-risk CRC patients may help in early detection of cancer

Lancet study links worldwide economic crisis to increased cancer mortality

New hydrogel-based biochip may help in early diagnosis of bowel cancer

Study provides better understanding of sequence of genetic events in colorectal cancer premalignancy

Mitoxantrone for MS linked to colorectal cancer risk

Study shows endoscopist knowledge of positive Cologuard result may enhance colonoscopy quality

Researchers identify mutations that may stimulate early cancer growth in precancerous colorectal tissue

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

Could a new test improve bowel cancer screening uptake? An interview with Professor Halloran

Diet experiments on Lynch syndrome mouse model may help in early detection of colon cancer

Targeting ERK and compensatory pathways with drug inhibitors halts colorectal cancer growth

New research solves mystery of why cetuximab drug proved futile for many colorectal cancer patients

Depressed cancer patients less likely to recover well after treatment

Mitoxantrone drug users more likely to develop colorectal cancer

Medicare policy puts low-income Americans at increased risk for colorectal cancer

Oophorectomy could increase colorectal cancer risk in both pre- and postmenopausal women

Bayer-new phase 3 liver cancer data

ATR-FTIR spectroscopy could be effective for detecting ulcerative colitis

Cholesterol-lowering drugs may not reduce colorectal cancer risk

Innovation in neuroscience drug discovery - eBook eBook

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Innovation in neuroscience drug discovery - eBook eBook

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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