Cytokines News and Research

Latest Cytokines News and Research

Gut microbiota-derived metabolite directly shapes immune responses in bacterial pneumonia

Sepsis and severe pneumonia are frequently accompanied by disruption of the gut microbiota, leading to immune dysfunction and increased susceptibility to secondary infections.

4 Mar 2026

Inflammatory signals from vesicles increase cancer cell aggressiveness and invasiveness

Pro-inflammatory M1 macrophages involved in immune responses accelerate the progression of melanoma through the extracellular vesicles they secrete, a recent study from the University of Eastern Finland shows. The findings were published in Cell Communication and Signaling.

3 Mar 2026

Study reveals cellular and metabolic landscape of lymph node metastasis in breast cancer

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that drive the spread of breast cancer.

2 Mar 2026

How zinc deficiency could worsen heart inflammation and what that means for patients

This review examines how zinc regulates inflammatory and redox signaling pathways involved in myocarditis and pericarditis, highlighting mechanisms such as NF-κB inhibition and the redox zinc switch. The authors conclude that maintaining optimal zinc status may support cardiovascular resilience, while emphasizing that clinical translation requires further targeted trials.

1 Mar 2026

Study identifies antiviral protein IFN-γ as a potential biomarker for Long COVID fatigue

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression.

23 Feb 2026

Gut microbiome may shape response to GLP-1 drugs, new review suggests

This review examines how GLP-1 receptor agonists and the gut microbiome influence one another through bile acid signaling, short-chain fatty acids, and inflammatory pathways. It explores how microbial composition may shape treatment response and highlights the need for controlled human studies to enable microbiome-informed precision therapy.

19 Feb 2026

IFN-γ identified as a powerful blood biomarker for Alzheimer’s

This study identifies IFN-γ as a crucial blood-based biomarker for Alzheimer's, revealing its role in microglial inflammation and genetic risk interactions.

19 Feb 2026

Study reveals coffee triggers distinct cytokine responses compared with pure caffeine

A randomized crossover pilot study in healthy adults found that coffee and isolated caffeine produce distinct short-term immune responses despite equivalent caffeine doses. The results suggest non-caffeine coffee compounds may influence cytokine activity and caffeine metabolism, although findings remain preliminary due to the small sample size.

19 Feb 2026

Macrophage immune memory depends on lingering interferon gamma

Researchers from the University of California, Los Angeles, have discovered that immune cells known as macrophages remain poised to fight repeat infections due to the persistent presence of signaling molecules left behind during previous infections.

18 Feb 2026

Do cocoa flavanols influence heart and fatty liver risk factors?

A recent Nutrients review examined whether cocoa-rich dark chocolate influences cardiovascular and metabolic dysfunction-associated steatotic liver disease risk factors through antioxidant, anti-inflammatory, and endothelial effects. Evidence suggests modest improvements in biomarkers, but most data come from short-term studies, so definitive clinical benefits remain unproven.

16 Feb 2026

Chronic inflammation shapes cancer progression and immunotherapy response

Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.

16 Feb 2026

Unlocking the potential of phytochemicals in rheumatoid arthritis treatment

Announcing a new article publication for BIO Integration journal. In recent years, phytochemicals and medicinal plants have increasingly been used to treat autoimmune diseases, such as rheumatoid arthritis (RA).

16 Feb 2026

Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation

Intranasal boosting after prior intramuscular COVID vaccination induced strong mucosal IgA responses in a small human cohort. These antibodies showed markedly enhanced neutralising activity against Omicron variants and evidence of immune memory reprogramming toward mucosal protection.

15 Feb 2026

Engineered Listeria boosts innate immunity against cancer

After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent booster of the immune system - and a potential weapon against cancer.

13 Feb 2026

Burn pit particles trigger lung inflammation through immune activation

A new study from National Jewish Health helps explain how exposure to burn pit smoke and desert dust may damage the lungs of military service members deployed to regions such as Afghanistan and Iraq.

7 Feb 2026

Eosinophils suppress tumor growth and recurrence in chordoma

Chordoma is a rare tumor characterized by poor prognosis, limited therapeutic options, and a high rate of recurrence. Despite advances in oncology, effective treatments for chordoma remain limited.

31 Jan 2026

Microneedle patches enhance acne treatment with dual drug delivery

Acne vulgaris affects a large proportion of adolescents and young adults and can lead to long-term scarring and psychological distress.

30 Jan 2026

PFOA exposure disrupts hormone signaling and impairs embryo implantation in mice

A new experimental study has found that perfluorooctanoic acid (PFOA), a widely used industrial chemical, can interfere with key biological processes required for successful embryo implantation, raising concerns about its potential impact on female fertility.

27 Jan 2026

How modern lifestyles reprogram the gut microbiome and shape disease risk

Modern lifestyle factors such as circadian disruption, sleep deprivation, stress, and exercise reshape the gut bacteriome and its metabolic outputs. These microbiome changes are linked to immune, metabolic, and cancer-related pathways, largely through evidence from animal models and observational human studies.

27 Jan 2026

Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease

Micro- and nanoplastics are increasingly detected in human tissues, including the brain, and experimental evidence suggests they can interact with biological pathways central to Parkinson’s disease pathology. This review synthesises mechanistic data indicating that plastic particles may influence protein aggregation, neuroinflammation, mitochondrial dysfunction, and the gut–brain axis, while emphasising the need for prospective human studies.

26 Jan 2026

Cytokines News and Research

Latest Cytokines News and Research

Gut microbiota-derived metabolite directly shapes immune responses in bacterial pneumonia

Inflammatory signals from vesicles increase cancer cell aggressiveness and invasiveness

Study reveals cellular and metabolic landscape of lymph node metastasis in breast cancer

How zinc deficiency could worsen heart inflammation and what that means for patients

Study identifies antiviral protein IFN-γ as a potential biomarker for Long COVID fatigue

Gut microbiome may shape response to GLP-1 drugs, new review suggests

IFN-γ identified as a powerful blood biomarker for Alzheimer’s

Study reveals coffee triggers distinct cytokine responses compared with pure caffeine

Macrophage immune memory depends on lingering interferon gamma

Do cocoa flavanols influence heart and fatty liver risk factors?

Chronic inflammation shapes cancer progression and immunotherapy response

Unlocking the potential of phytochemicals in rheumatoid arthritis treatment

Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation

Engineered Listeria boosts innate immunity against cancer

Burn pit particles trigger lung inflammation through immune activation

Eosinophils suppress tumor growth and recurrence in chordoma

Microneedle patches enhance acne treatment with dual drug delivery

PFOA exposure disrupts hormone signaling and impairs embryo implantation in mice

How modern lifestyles reprogram the gut microbiome and shape disease risk

Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease

Industry Focus eBook - Infectious Diseases (2nd Edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

Cytokines News and Research

Latest Cytokines News and Research

Industry Focus eBook - Infectious Diseases (2nd Edition) eBook

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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