Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Treatment Options for Children with Depression

Can Depression and Anxiety Occur Together?

How Can I Tell if My Child is Depressed?

Treatment of Depression

Prisoner Depression and Low Mood

Intrusive Thoughts and Depression

Antidepressants and Weight Changes

Food Insecurity and Depression

Ghrelin and Depression

How is Depression in Children Diagnosed?

How Does Your Diet Affect Depression?

See more featured articles »

Genes and Depression

Symptoms of Depression

Link Between Chronic Illness and Depression

Supporting Children with Mental Health Disorders

5 Facts You May Not Know About Depression

Causes of Depression

Depression Diagnosis

Contributing Factors to Post-Adoption Depression

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

Situational Depression: Symptoms, Causes, Treatments

Depression and Sleep Length

Depression in children

Latest Depression News and Research

Religious faith linked to lower psychological distress during Covid-19 lockdown

Two Cambridge-led studies suggest that the psychological distress caused by lockdowns (UK) and experience of infection (US) was reduced among those of faith compared to non-religious people.

1 Feb 2026

First-of-its-kind clinical guidance on psychedelic medicine released

Unbound Medicine and Johns Hopkins Medicine today announced a significant expansion of the Johns Hopkins Psychiatry POC-IT Guide, a leading digital resource for clinicians and trainees worldwide.

30 Jan 2026

King’s researchers help transform UK mental health research infrastructure

King’s researchers will help transform mental health data, clinical trials and industry partnerships as part of the UK Government’s Mental Health Goals programme.

30 Jan 2026

Metacognitive therapy speeds return to work and saves costs

Many people with different mental health problems can be absent from work for a long time. But new results give hope that more people can recover and return to work sooner.

30 Jan 2026

WHO launches guide to address mental health and stigma for people living with NTDs

Marking World Neglected Tropical Diseases (NTDs) Day, the World Health Organization (WHO) warns that millions of people living with NTDs continue to face profound and often unseen suffering due to discrimination, social stigma and untreated mental health conditions.

30 Jan 2026

The role of school health services in adolescent wellness

She has written a doctoral thesis on health-related quality of life among children and young people in Agder.

30 Jan 2026

Biomarker discovery may pave the way for early diagnosis of Parkinson's

A team led by researchers at Chalmers University of Technology, Sweden, has succeeded in identifying biomarkers for Parkinson's disease in its earliest stages, before extensive brain damage has occurred.

29 Jan 2026

Research reveals dual impact of brain stimulation on people with depression and anxiety

Research investigating the effects of transcranial direct current stimulation (tDCS) on individuals with depression and comorbid anxiety reveals a dual impact of this noninvasive form of brain stimulation.

29 Jan 2026

Sharing thoughts and feelings may enhance recovery in stroke survivors

Stroke survivors who were uncomfortable sharing their thoughts and feelings about their condition and future had slower physical and cognitive recovery after their stroke, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2026.

29 Jan 2026

New calculator accurately estimates the risk of dementia after a stroke

A new risk calculator accurately estimated the likelihood of adults developing dementia within ten years after a stroke, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2026.

29 Jan 2026

Smartwatch app to track social interactions of stroke survivors may help maximize recovery

A smartwatch app designed to measure social interactions of hospitalized stroke survivors may enable new treatments to preserve or enhance cognition, social engagement and quality of life after a stroke, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2026.

29 Jan 2026

Neighborhood disadvantage accelerates biological aging through emotional distress

While scientists have long known that living in a disadvantaged neighborhood is associated with biological symptoms of accelerated aging, emotional distress accounts for a significant portion of these effects, researchers found in a recent study.

29 Jan 2026

Antidepressant use does not worsen early outcomes after traumatic brain injury

Taking certain antidepressants at the time of a traumatic brain injury (TBI) is not associated with an increased risk of death, brain surgery or longer hospital stays, according to a study published on January 28, 2026, in Neurology, the medical journal of the American Academy of Neurology.

28 Jan 2026

Eating melatonin-rich foods is linked to lower obesity and depression rates

This cross-sectional analysis of 8,320 Brazilian adults quantified melatonin intake from habitual diets and examined associations with multiple chronic health outcomes. Higher dietary melatonin intake was inversely associated with obesity and depression in a non-linear pattern, with no significant associations observed for other conditions.

28 Jan 2026

Transcranial magnetic stimulation can be a cost-effective treatment option for depression

A major new study has found that transcranial magnetic stimulation (TMS), which applies magnetic energy to the brain, can be a cost-effective treatment option for the NHS in treating moderate and severe forms of depression that have not responded to other treatments.

27 Jan 2026

Study isolates mania-specific genetic architecture in bipolar disorder

Researchers at King's College London and the University of Florence have, for the first time, identified the specific genetic blueprint of mania, the defining feature of bipolar disorder.

27 Jan 2026

Depression and anxiety together raise long COVID risk in older women

Older women who have a history of both depression and anxiety had a 78% higher risk of developing long COVID after a SARS-CoV-2 infection, report University of California San Diego researchers in the Jan. 27, 2026 online edition of the journal Menopause.

27 Jan 2026

HHCM awards $566K to advance psychedelic end-of-life care research

Healing Hearts, Changing Minds (HHCM) today announced the seven awardees of Walking Each Other Home: A Fund to Promote Psychedelic Compassion for End-of-Life Care, a $566,260 philanthropic initiative supporting innovation, compassion, and dignity for people at life's end.

27 Jan 2026

Menopause associated with reduced brain volume and increased anxiety symptoms

Menopause is linked to reductions in grey matter volume in key brain regions as well as increased levels of anxiety and depression and difficulties with sleep, according to new research from the University of Cambridge.

27 Jan 2026

Olive oil type matters for cognition and gut health in older adults

Higher intake of virgin and total olive oil was associated with modest but significant improvements in cognitive performance over two years in older adults with metabolic syndrome. These associations were partly linked to gut microbiota composition, with specific taxa such as Adlercreutzia contributing a small mediating effect.

26 Jan 2026