Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Depression and Sleep Length

How Does Your Diet Affect Depression?

Link Between Chronic Illness and Depression

Treatment Options for Children with Depression

5 Facts You May Not Know About Depression

Causes of Depression

Ghrelin and Depression

Symptoms of Depression

Food Insecurity and Depression

How is Depression in Children Diagnosed?

Intrusive Thoughts and Depression

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Genes and Depression

Treatment of Depression

Prisoner Depression and Low Mood

How Can I Tell if My Child is Depressed?

Antidepressants and Weight Changes

Depression in children

Can Depression and Anxiety Occur Together?

Contributing Factors to Post-Adoption Depression

Situational Depression: Symptoms, Causes, Treatments

Depression Diagnosis

Supporting Children with Mental Health Disorders

Latest Depression News and Research

Researchers find no meaningful health impacts from wind energy turbines

A joint research paper involving work from the University of Pittsburgh has found that, despite some public concern, turbines used to produce wind energy are not responsible for any detectable adverse health outcomes.

21 May 2026

Machine learning lifestyle coaching helps reduce major depressive symptoms

More than 21% of U.S. adults experience depression, greatly impacting their quality of life. Many people with mild‑to‑moderate depression can improve their symptoms by adjusting daily habits like sleep, exercise, diet and social interaction, according to Jyoti Mishra, PhD, associate professor of psychiatry at University of California San Diego School of Medicine.

21 May 2026

First-of-its-kind pregnancy hormone test reveals why female IBD patients face severe symptom flares

Inflammatory bowel disease (IBD), which comprises the inflammatory conditions Crohn's disease and ulcerative colitis, affects about 1.6 million Americans, many of whom cannot be effectively treated.

21 May 2026

Key neural circuit helps the brain “change gears”

Most people have experienced the feeling: switching from one task to another, only to find the brain momentarily stuck in the old mode of thinking. Sometimes, even after realizing a strategy no longer works, the mind keeps returning to it anyway.

21 May 2026

Anti-inflammatory drug tocilizumab shows promise for difficult-to-treat depression

Immunotherapy could be a promising new treatment option for patients with difficult-to-treat depression. This is a key finding from a University of Bristol-led pilot randomised controlled clinical trial, published in JAMA Psychiatry today [20 May].

20 May 2026

Plant-based eye drops harness photosynthesis to heal dry eyes

What if your eyes could use light to heal themselves? Drawing inspiration from how plants harness sunlight, researchers at the National University of Singapore (NUS) are pioneering a revolutionary treatment for dry eye disease.

20 May 2026

Aerobic exercise mitigates nanoplastic damage in female zebrafish

Using female zebrafish as a model, researchers have found that aerobic exercise may influence various connections in the body to lessen the damaging health impacts of environmental nanoplastics.

20 May 2026

How food and alcohol cues leave different signatures in the brain

Food and alcohol cues appear to engage partially distinct EEG oscillatory patterns, with food cues linked mainly to increased delta activity and alcohol-related processing showing alpha and delta differences in key contrasts. The effects were strongest in participants with relatively higher AUDIT scores, but neural changes were small and subjective cue responses were more robust.

20 May 2026

Women may face greater cognitive impact from dementia risk factors

Researchers from the University of California San Diego School of Medicine found that women not only experience a higher burden of certain modifiable dementia risk factors, but also appear more vulnerable to their effects on cognitive function.

20 May 2026

Anxiety and depression linked to mirror opposite sides of the brain's emotional center

A longitudinal study tracking children over a period of seven years identified distinct brain-wave patterns emerging from age 9 can forecast a child's vulnerability to anxiety or depression by age 13.

20 May 2026

Massive global analysis examines cognitive development in children of affected parents

A new study led by Murdoch University has found that children of parents with severe mental illness are more likely to experience cognitive difficulties.

19 May 2026

Vitamin D deficiency linked to higher postoperative breast cancer pain

Vitamin D deficiency is associated with more moderate to severe pain following breast cancer surgery and an increased consumption of opioid drugs, finds research published online in the journal Regional Anesthesia & Pain Medicine.

19 May 2026

Experimental smartphone game quickly identifies patients with depression

An experimental diagnostic tool in the form of a computer game was able to quickly identify patients with depression based on anhedonia, a key feature of the disease, a new study shows.

19 May 2026

Psychologist debunks myth that sexual desire disappears with age

Sexuality is an important part of life - even when we grow old. The idea that desire disappears with age is a myth that needs to be debunked, argues a psychologist who has researched older adults' sex lives.

19 May 2026

Nutrition education improves diet quality in university students

Nutrition education at universities shows promise in improving dietary habits and mental well-being, highlighting the importance of healthy eating for students.

19 May 2026

Combination therapy shows promise in maintaining lower suicidal thoughts over time

New research published online today in the American Journal of Psychiatry finds that low-dose buprenorphine, given after a single ketamine infusion, significantly sustained reductions in suicidal ideation in adults with major depressive disorder.

19 May 2026

Mental disorders affect one in three pregnant women, and violence may be a key driver

A systematic review and meta-analysis of 18 studies involving 17,380 pregnant women found that common mental disorders affected about one-third of participants across studies from Africa, Asia, and South America. The analysis found strong regional variation and identified intimate partner violence as the only statistically significant risk factor, with affected women having about 2.6-fold higher odds of CMDs.

18 May 2026

Integrated care needed for lifelong Polyendocrine Ovarian Syndrome management

Polycystic Ovary Syndrome, which has just been renamed Polyendocrine Ovarian Syndrome (PMOS), is the most common hormonal and metabolic disorder affecting women of reproductive age, impacting up to 13% of this population and contributing to nearly 40% of infertility cases worldwide.

18 May 2026

Psilocybin offers fast-acting alternative to traditional antidepressants

A single dose of the psychedelic substance psilocybin can provide rapid relief from depressive symptoms – within just a few days. This is shown by the first randomised, double-blind study in Sweden of psilocybin for depression. The effect persisted for over three months, according to researchers at Karolinska Institutet.

15 May 2026

Addressing depression and anxiety in primary care improves chronic pain management

A study published this month in the American Journal of Managed Care explores how integrating behavioral health care into primary care can improve outcomes and be cost-effective for adults with depression, anxiety and chronic pain who are on long-term opioid therapy.

15 May 2026