Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

5 Facts You May Not Know About Depression

Situational Depression: Symptoms, Causes, Treatments

Treatment Options for Children with Depression

Intrusive Thoughts and Depression

Contributing Factors to Post-Adoption Depression

Supporting Children with Mental Health Disorders

How Can I Tell if My Child is Depressed?

Antidepressants and Weight Changes

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

Causes of Depression

Depression and Sleep Length

See more featured articles »

Treatment of Depression

Symptoms of Depression

Genes and Depression

Link Between Chronic Illness and Depression

Depression in children

How Does Your Diet Affect Depression?

Depression Diagnosis

Food Insecurity and Depression

Can Depression and Anxiety Occur Together?

Ghrelin and Depression

How is Depression in Children Diagnosed?

Prisoner Depression and Low Mood

Latest Depression News and Research

Experimental vaccine protects against fentanyl and related opioids

Fentanyl and related variants of the synthetic opioid kill more Americans each year than car accidents and gun violence combined. In too-high doses, the drugs hijack brain chemistry and shut down the signals that control breathing.

11 Jun 2026

Self-help program improves mental health among displaced refugees

A simple self-help workbook paired with brief phone support can make a measurable difference to the mental health of displaced refugees, a new study has found.

11 Jun 2026

High social media use increases mental health risks for adolescents

Adolescents who spend at least two hours a day on social media are more likely to experience depressive symptoms and poorer wellbeing, with the strongest effects in early adolescence, according to new research.

11 Jun 2026

Chronic pancreatitis care must expand beyond simple pain management

Chronic pancreatitis (CP) diminishes quality-of-life (QoL) across mobility, self-care, daily activities, mental health, and pain-not just abdominal discomfort-according to a new Mayo Clinic study available online on August 27, 2025, and published in Volume 9, Issue 1 of the Journal of Pancreatology on March 30, 2026.

11 Jun 2026

Remote work explains part of the post-pandemic rise in mental distress

Researchers found that workers in remote jobs spent more time alone after the COVID-19 pandemic and experienced greater psychological distress than those in non-remote jobs. The effects were strongest among people living alone, suggesting that reduced everyday social contact may be an important cost of remote work.

10 Jun 2026

Quality of life for working-age Japanese adults declines steadily

The COVID-19 pandemic upended many aspects of everyday life, including socialization, office work, and medical care, but little data was available to quantify how those changes affected quality of life both during the pandemic and over the long term, particularly on a national scale.

10 Jun 2026

Proactive brain training strengthens mental wellness before challenges arise

A new study recently published in the peer-reviewed journal Frontiers in Psychology challenges the traditional, reactive model of mental health care by demonstrating that proactive brain training can strengthen the human mind before mental health challenges take root.

10 Jun 2026

European study connects youth mental health to economic parity

Xabi Martinez-Mendia, a researcher at the EHU-University of the Basque Country, has analysed how adolescent psychotropic drug consumption is linked to gender inequality and economic factors in 32 European countries.

10 Jun 2026

More daily steps translate to improved mental health and better sleep among college students

University students who aren't always enthused about walking across campus for class can take heart in new research that suggests lots of daily steps translates to improved mental health and better sleep.

9 Jun 2026

Large study uncovers brain network differences in bipolar disorder

New research from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has discovered subtle but widespread differences in the brain's communication networks in people with bipolar disorder, offering new insight into how illness severity and treatment may relate to brain wiring.

9 Jun 2026

New study identifies brain circuit behind TMS’s antidepressant effects

A circuit that runs from the prefrontal cortex near the front of the brain to a deeper brain structure called the insular cortex appears to mediate the antidepressant effects of a newer form of transcranial magnetic stimulation (TMS), according to a study led by Weill Cornell Medicine investigators.

9 Jun 2026

Massive genetic study uncovers new insights into anxiety risk

A study led by researchers at King’s College London and QIMR Berghofer medical research institute analysed genetic data on anxiety symptoms in 693,869 people of European ancestry, revealing new insight into the genetic pathways involved in the condition.

9 Jun 2026

Fathers shape childhood obesity risk long before birth

New research highlights fathers' influence on childhood obesity risk through sperm changes, lifestyle, and parenting, urging inclusive prevention strategies.

9 Jun 2026

Antidepressants trigger opposite reactions in different groups of serotonin-producing brain cells

A new study has uncovered how antidepressants affect different groups of serotonin-producing brain cells in opposite ways, offering new insights into why selective serotonin reuptake inhibitors (SSRIs) can cause unpleasant side effects at the start of treatment but lead to symptom relief over time.

8 Jun 2026

Early outdoor play reduces future mental health risks in children

Children who spend more time playing outdoors between the ages of two and four may be less likely to develop emotional and behavioural difficulties later in childhood.

8 Jun 2026

Improved non-invasive brain stimulation targets deep-seated neurological disorders

Brain stimulation techniques can correct abnormal activity in the neural circuits involved in conditions such as Parkinson's disease and depression. However, current transcranial stimulation methods delivered through the scalp reach only the brain's surface, limiting their effectiveness.

8 Jun 2026