Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Treatment of Depression

Causes of Depression

Treatment Options for Children with Depression

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

Food Insecurity and Depression

Symptoms of Depression

5 Facts You May Not Know About Depression

Depression and Sleep Length

Link Between Chronic Illness and Depression

Supporting Children with Mental Health Disorders

Depression in children

See more featured articles »

Prisoner Depression and Low Mood

Can Depression and Anxiety Occur Together?

Ghrelin and Depression

How Can I Tell if My Child is Depressed?

How is Depression in Children Diagnosed?

Contributing Factors to Post-Adoption Depression

Situational Depression: Symptoms, Causes, Treatments

How Does Your Diet Affect Depression?

Intrusive Thoughts and Depression

Genes and Depression

Depression Diagnosis

Antidepressants and Weight Changes

Latest Depression News and Research

Mental health stigma may deter treatment seeking in Japan

A UC Riverside-led study of mental health stigma in Japan has found a striking gap between the need for treatment and people's willingness to seek it, with high levels of social distancing toward people with mental illness serving as a potential barrier.

6 Oct 2026

Nature recognized as key component of lifestyle medicine and health

The American College of Lifestyle Medicine (ACLM) today welcomed a resolution adopted by the Association of Fish and Wildlife Agencies (AFWA) that recognizes nature's role in supporting human health and calls for greater collaboration among the conservation, healthcare and research communities.

5 Oct 2026

Global experts call for coordinated action on digital health risks

The way digital technologies are currently built and governed creates real risks to health worldwide, alongside genuine benefits, according to a new three paper Series authored by 13 global experts, published in The Lancet.

5 Oct 2026

Existing drug could target neuroinflammation in Alzheimer's patients

Inflammatory conditions in the brain, including traumatic brain injury and degenerative diseases like Alzheimer's could be targeted with an existing drug thanks to new research that shows it can work in brain cells.

5 Oct 2026

Study urges parents to take sibling aggression more seriously

Sibling aggression takes many forms, like hitting, shoving, threatening or calling names. Although sibling aggression is widespread and can shape people for years, it hasn't been studied well by psychological researchers.

5 Oct 2026

Patient navigators significantly improve postpartum care for low-income mothers

While the transition to motherhood can be challenging for anyone, barriers such as inadequate health literacy, unreliable transportation, navigating a complex health care system, limited access to childcare or insecure housing can be the tipping point between a new mom accessing needed care or going without it.

5 Oct 2026

Genetic links to ADHD, autism and depression changed with age

The study examines genetic liability for neurodevelopmental disorders, revealing its impact on social functioning and educational attainment across life stages.

5 Oct 2026

Online approach helped patients manage anxiety after chest pain

The PACER study reveals that peer-supported CBT significantly lowers anxiety in low-risk chest pain patients, enhancing mental health in emergency settings.

2 Oct 2026

NIH-funded trials will test pregnenolone for addiction and depression

Center for BrainHealth investigator Francesca Filbey, PhD, and UTSW investigator Sherwood Brown, MD, PhD, have secured two awards from the National Institutes of Health (NIH) to fund two major collaborative studies investigating whether the naturally occurring neurosteroid pregnenolone can help treat substance use disorders and co-occurring depression.

1 Oct 2026

New framework maps depression symptoms to unique brain circuits

A research team from the Sant Pau Research Institute (IR Sant Pau) has published a scientific review proposing a paradigm shift in the way depression is understood and studied.

1 Oct 2026

New trial tests if diet can reduce bipolar depression symptoms

A clinical trial is set to test whether diet could help reduce depressive symptoms in people with bipolar disorder, comparing a high fat, low carbohydrate diet with standard NHS healthy eating advice.

1 Oct 2026

Cognitive tests may not tell the whole story about memory concerns

This study highlights the link between blood biomarkers and dementia risk in subjective cognitive decline, emphasizing prevention and lifestyle changes.

1 Oct 2026

Real-world data reveals higher reported GLP-1 side effects in female patients

The second of a Series of papers presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in The Lancet Obstetrics, Gynaecology & Women's Health discusses the wide-ranging issues relating to use of GLP-1 RA drug use in women.

1 Oct 2026

Study examines the real-world use of GLP-1 RA drugs in children and young people

New research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) has examined the real-world use of GLP-1 receptor agonist (GLP-1 RA) drugs in children and young people in Germany, Austria and Luxembourg.

30 Sep 2026

Study connects food insecurity to mental health in young mothers

A new review of research from across sub-Saharan Africa found that inadequate access to food is linked to depression, suicide attempts, HIV vulnerabilities, and poorer sexual and reproductive health outcomes among adolescent mothers.

30 Sep 2026

Positive parenting, consistent discipline reduce children's behavioral and emotional problems

There's no one right way to raise a child, but different patterns of parenting are associated with how kids behave.

30 Sep 2026

Young adults using AI for health questions may screen positive for anxiety and depression

Young adults who use generative artificial intelligence to ask health-related questions are more likely to screen positive for clinically significant anxiety and depression than those not using the AI tool for health issues, according to a new study led by University of Florida researcher Yusen Zhai.

30 Sep 2026

Owning a smartphone at 12 linked to eating disorder symptoms

Early smartphone use is linked to a rise in eating disorder symptoms among adolescents, indicating potential mental health implications that require attention.

30 Sep 2026

Maternal depression linked to neurodevelopmental disorders in children

Children of mothers with depression had higher rates of certain neurodevelopmental disorders regardless of whether they were exposed to antidepressants in the womb, reports a new study led by Saraid McIlvride of the University of Glasgow, UK, published September 29th in the open access journal PLOS Medicine.

29 Sep 2026

Social connection has a price, and it varies from person to person

Researchers found that people were willing to spend slightly more on social than on non-social experiences, suggesting that companionship has measurable economic value. Greater perceived social support was associated with more social choices and spending, while higher autistic-trait scores and broader social dysfunction were associated with lower valuation of social experiences.

29 Sep 2026