Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Prisoner Depression and Low Mood

Treatment of Depression

Supporting Children with Mental Health Disorders

Depression and Sleep Length

Antidepressants and Weight Changes

Contributing Factors to Post-Adoption Depression

Ghrelin and Depression

Can Depression and Anxiety Occur Together?

Intrusive Thoughts and Depression

Treatment Options for Children with Depression

Situational Depression: Symptoms, Causes, Treatments

See more featured articles »

Genes and Depression

Causes of Depression

Depression in children

How Can I Tell if My Child is Depressed?

Symptoms of Depression

How is Depression in Children Diagnosed?

5 Facts You May Not Know About Depression

Food Insecurity and Depression

How Does Your Diet Affect Depression?

Link Between Chronic Illness and Depression

The Science Behind the Winter Blues: Understanding Seasonal Affective Disorder

Depression Diagnosis

Latest Depression News and Research

Survey highlights widespread emotional impact of cancer on patients and their families

A cancer diagnosis is a life-changing event for patients that can cause short- and long-term mental health concerns as they shift to living within a new timeline driven by weeks or months between medical follow-up appointments.

15 Jul 2025

Person-focused approach explains distinct autism genetic subtypes

Research identifies four autism classes driven by different genes, enhancing understanding of ASD's genetic complexity and improving diagnostic approaches.

15 Jul 2025

Research explores the link between lower micronutrient levels and chronic pain

Lower levels of certain vitamins and minerals were found to be associated with chronic pain in a recently completed study led by researchers at the University of Arizona Health Sciences and published in Pain Practice.

15 Jul 2025

Targeting vasopressin neurons alleviates postpartum depression

Researchers at Nanjing University's School of Life Sciences, in collaboration with colleagues from Nanjing Drum Tower Hospital, the Icahn School of Medicine at Mount Sinai, and the Peng Cheng Laboratory, have identified a specific brain circuit that eases depressive-like behaviors in a mouse model of postpartum depression, providing a promising target for future treatments. This work addresses how sudden drops in estrogen after childbirth can trigger mood disturbances.

15 Jul 2025

Insomnia may be the missing link between ADHD and low life satisfaction

Insomnia could explain why adults with ADHD traits report having a lower quality of life, according to new research led by the University of Southampton and the Netherlands Institute of Neuroscience.

15 Jul 2025

New WHO guidelines recommend injectable lenacapavir for HIV prevention

The World Health Organization (WHO) released today new guidelines recommending the use of injectable lenacapavir (LEN) twice a year as an additional pre-exposure prophylaxis (PrEP) option for HIV prevention, in a landmark policy action that could help reshape the global HIV response.

14 Jul 2025

Ultra-processed foods threaten brain health in kids and teens, review warns

Children, adolescents, and unborn babies exposed to high levels of ultra-processed foods (UPFs) face increased risks of impaired brain development, cognitive deficits, and long-term mental health challenges. The review underscores how UPF-driven changes in reward pathways, nutrient deficits, inflammation, and the gut–brain axis can have lasting impacts across generations.

13 Jul 2025

Improving parent well-being may directly benefit the health of children with chronic conditions

Strong emotional links between children with chronic conditions and their family caregivers suggest that improving parent well-being may directly benefit a child's overall health and coping mechanisms, according to a study being presented Saturday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

12 Jul 2025

Study reveals dopamine sends precise signals rather than broad brainwide messages

A new study from the University of Colorado Anschutz Medical Campus has upended decades of neuroscience dogma, revealing that dopamine, a neurotransmitter critical for movement, motivation, learning and mood, communicates in the brain with extraordinary precision, not broad diffusion as previously believed.

12 Jul 2025

Prefrontal cortex RNA drives female-specific brain resilience to depression

A traditionally overlooked type of RNA plays an important role in promoting resilience to depression-but only in females.

12 Jul 2025

Advancing emotional and navigational interactions through flexible electret tactile feedback actuator

The advancements in tactile perception and feedback technologies have propelled the interaction between humans and the digital realm, spurring innovative applications across various fields, including virtual reality, augmented reality, disability assistance, and communication.

12 Jul 2025

Brain protein associated with aging not linked to youth contact sports

In recent years, some scientists and advocates have warned that playing contact sports like football and hockey may increase the risk of brain diseases like Alzheimer's disease or chronic traumatic encephalopathy (CTE) due to a buildup of a specific protein in the brain.

11 Jul 2025

Maternal depression found to disrupt key parenting behaviors

Mothers experiencing depression have considerable challenges across multiple parenting domains, according to a global systematic review published in the July issue of Harvard Review of Psychiatry, part of the Lippincott portfolio from Wolters Kluwer.

11 Jul 2025

Maltreatment in early childhood tied to lasting behavioral challenges

Childhood maltreatment leaves deep and lasting marks that have far-reaching consequences, extending beyond immediate trauma and affecting survivors in ways that are often invisible and misunderstood.

11 Jul 2025

Premenstrual symptoms linked to higher risk of cardiovascular disease

Women diagnosed with premenstrual symptoms have a slightly increased risk of developing cardiovascular disease later in life.

11 Jul 2025

Researchers create over 400 types of nerve cells from stem cells

Nerve cells are not just nerve cells. Depending on how finely we distinguish, there are several hundred to several thousand different types of nerve cell in the human brain according to the latest calculations.

11 Jul 2025

Breakthrough research uncovers multiple autism subtypes with unique traits

Researchers at Princeton University and the Simons Foundation have identified four clinically and biologically distinct subtypes of autism, marking a transformative step in understanding the condition's genetic underpinnings and potential for personalized care.

10 Jul 2025