Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life.

Clinical Depression: Diagnosis, Causes & Treatment

Depression is a clinical condition that, contrary to popular opinion, cannot simply be overcome with time and it needs to be treated.

Prisoner Depression and Low Mood

Can Depression and Anxiety Occur Together?

Genes and Depression

How Can I Tell if My Child is Depressed?

Supporting Children with Mental Health Disorders

Intrusive Thoughts and Depression

Treatment Options for Children with Depression

Food Insecurity and Depression

Link Between Chronic Illness and Depression

Ghrelin and Depression

Treatment of Depression

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Depression in children

Symptoms of Depression

5 Facts You May Not Know About Depression

Depression Diagnosis

Antidepressants and Weight Changes

Depression and Sleep Length

How is Depression in Children Diagnosed?

Latest Depression News and Research

Childhood unpredictability linked to higher mental health risks

Children who grow up in unpredictable environments may face elevated risks for depression, anxiety, sleep disorders and other mental health challenges, according to a new study by researchers at the University of California, Irvine, Chapman University and Rady Children's Hospital Orange County, formerly called Children's Hospital of Orange County.

21 Jul 2026

Distributed neural networks make decoding cognition vastly harder than movement

Brain-computer interfaces (BCIs) have made remarkable progress restoring movement and speech in people with paralysis.

21 Jul 2026

Researchers uncover brain target to counter fentanyl-induced slow breathing

Fentanyl causes symptoms that can lead to death from overdose. One of these symptoms is slow breathing, which deprives drug users of oxygen.

20 Jul 2026

Hippocampal damage linked to memory loss and apathy

People with autoimmune limbic encephalitis experience memory loss associated with damage to their hippocampus.

20 Jul 2026

Study links severe floods to higher opioid overdose deaths in rural Appalachia

Severe flooding may contribute to higher mortality rates from opioid use in rural Appalachia, according to a study by researchers at Penn State.

20 Jul 2026

Gut microbial metabolites may shape vulnerability to stress-related mental disorders

Gut microbiome-derived metabolites may influence stress-related mental disorders through neural, immune, endocrine, and epigenetic pathways. Evidence is strongest for depression and preclinical models, while larger longitudinal human studies are needed to establish causality and clinical value.

20 Jul 2026

Study reveals how adolescent brain remodeling reshapes memory retrieval

Scientists have long known that the human brain continues developing well beyond the teenage years, with important changes involving decision-making and emotional regulation extending into the mid-to-late 20s.

17 Jul 2026

Training helps pediatricians independently treat child anxiety and depression

Pediatricians who participated in the collaborative mental health program at Ann & Robert H. Lurie Children's Hospital of Chicago were more likely to diagnose and treat anxiety and depression in kids without reliance on additional support from specialists, according to a study published in Academic Pediatrics.

17 Jul 2026

Genetic discovery reveals biological cause of excessive sweating disorder

An international research team led by Prof. Dr Frank Bosmanbs (Vrije Universiteit Brussel) has discovered a major genetic cause of hyperhidrosis (chronic and excessive sweating).

17 Jul 2026

ECT-like brain stimulation triggers unexpected nuclear reprogramming in mature neurons

Nearly 90 years after Ugo Cerletti and Lucio Bini introduced electroconvulsive therapy (ECT), brain stimulation therapies such as ECT and Repetitive Transcranial Magnetic Stimulation (rTMS) are common in psychiatry because they are highly effective for treating depression and schizophrenia, yet their cellular mechanisms remain poorly understood

17 Jul 2026

Scientists discover master regulator gene network behind complex psychiatric disorders

A study by the University of Barcelona has identified nearly 20 genes that could contribute to some people being more susceptible to depression, anxiety and traits such as irritability and neuroticism.

17 Jul 2026

New model improves short- and long-term disease risk prediction

Researchers developed ALADYNOULLI, a Bayesian generative model that combines longitudinal health records, age, and polygenic risk to identify reproducible disease signatures across more than 683,000 participants. In UK Biobank testing, the framework achieved stronger short- and long-term risk discrimination than established clinical scores while revealing disease subgroups and genetic associations.

16 Jul 2026

Online harassment and screen time linked to suicidal thoughts

In the digital age, adolescents and young adults increasingly form social connections through online spaces, including social media, gaming and messaging platforms, which serve as venues for identity exploration, peer connection and emotional validation.

16 Jul 2026

Study highlights communication gaps between cancer survivors and providers on cannabis

For many cancer survivors, cannabis has become part of how they manage symptoms such as pain, nausea and anxiety.

16 Jul 2026

Federal nicotine reduction strategy could boost productivity and save lives

Implementing a federal nicotine reduction strategy may prevent millions of premature deaths, boost productivity, and significantly close smoking disparity gaps for individuals with major depression, according to Rutgers Health researchers.

16 Jul 2026

Endometriosis affects multiple body systems beyond pelvic pain

Migraines, digestive problems, anxiety, and depression can be part of endometriosis, although they are often interpreted as separate conditions.

16 Jul 2026

Sleeping longer may signal early Alzheimer's-related brain changes

Regularly sleeping long hours each night is associated with higher levels of an Alzheimer's-related protein in the blood, even accounting for other health factors, suggests a new study from UT Health San Antonio, the academic health center of The University of Texas at San Antonio.

15 Jul 2026

Experts recommend renaming PCOS to better reflect whole-body impacts

A condition affecting approximately 170 million adolescents and women worldwide has a new name – one that better reflects its complexity and far-reaching health impacts.

15 Jul 2026

GLP-1 receptor activation linked to lower depression and bipolar disorder odds

Genetic analyses linked BMI-related GLP-1 receptor activation to better mental well-being and lower odds of major depressive disorder and bipolar disorder. The findings do not prove that GLP-1 receptor agonist drugs treat psychiatric conditions, and randomized clinical trials are still needed.

15 Jul 2026

Poor sleep alters brain communication networks differently across adult lifespan

Have trouble sleeping? The reason may depend in part on your age. A recent study including psychology researchers from Binghamton University, State University of New York investigates how poor sleep alters brain communication across the adult lifespan, specifically examining how these changes vary by age and biological sex.

14 Jul 2026