Lupus News and Research

Latest Lupus News and Research

Advances in Virus Epigenetics

Growing evidence shows viruses exploit epigenetic processes to control their life cycles but epigentic regulation of viral infections is not fully understood.

From Chromatrap® - Porvair Sciences Ltd 25 Aug 2020

Hydroxychloroquine is not a possible defense against COVID-19, study shows

Researchers at Case Western Reserve University have added to the growing body of understanding about how hydroxychloroquine (HCQ) is not a possible defense against COVID-19.

17 Aug 2020

Mysterious enzyme inhibits inflammation in blood vessels, LJI study shows

Scrape your knee, and you'll see some red puffiness appear around the injury. This is inflammation, and it is driven by the immune system.

23 Jul 2020

Evidence of SARS-CoV-2 placental infection in mild COVID-19

Now, a new study published on the preprint server medRxiv* in July 2020 reveals evidence of placental infection and hypoxia, despite the lack of serious symptoms in the mother.

16 Jul 2020

One in three young adults at a higher risk of severe COVID-19 due to smoking, vaping

Now, a new study shows that about one in three young adults may be at risk of severe COVID-19 due to smoking and vaping habits.

14 Jul 2020

Study shows smoking is associated with a higher likelihood of COVID-19 progression

As the number of young adults infected with the coronavirus surges throughout the nation, a new study by researchers at UCSF Benioff Children's Hospitals indicates that youth may not shield people from serious disease.

13 Jul 2020

New method helps pinpoint new potential therapeutic targets for lupus

A team of researchers from Children's Hospital of Philadelphia (CHOP) used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders.

8 Jul 2020

Research sheds light on mysterious COVID-19 related hyperinflammatory shock in children

The ongoing COVID-19 pandemic has cost hundreds of thousands of human lives, besides more than 11 million cases. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the disease was initially thought to be more severe in the elderly and those with pre-existing medical conditions. However, it started to manifest in children after the peak of the first wave.

7 Jul 2020

ACE inhibition in kidney could influence pathogenesis of SARS-CoV-2

The dynamics of angiotensin-converting enzyme 2 (ACE2) expression in the kidney could have implications for the infectivity and pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), say researchers.

24 Jun 2020

Colombian corona hounds: SAR-CoV-2 detection by dogs

A new Colombian study published on the preprint server bioRxiv in June 2020 describes the use of trained dogs to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected humans by scent alone. This would allow uninfected people to work together safely, rescuing the economy without driving up medical costs.

23 Jun 2020

Researchers find prothrombotic antibodies in patients with COVID-19

Even as the COVID-19 pandemic continues to spread across the world, researchers are still trying to understand the many ways in which it can manifest and its pathogenesis. A new report published on the preprint server medRxiv* in June 2020 shows that one possible mechanism of disease in COVID-19 is the production of antiphospholipid antibodies.

19 Jun 2020

Study initiates hydroxychloroquine clinical trial to prevent COVID-19 in healthy people

Rush University Medical Center has opened enrollment for a new clinical trial investigating whether the drug hydroxychloroquine is better than a placebo in preventing COVID-19 infection in healthy people working in health care settings.

12 Jun 2020

Turning autoimmunity drugs into anti-cancer treatments

Professor Mark Cragg speaks to News-Medical about his research which involves turning autoimmunity drugs into anti-cancer treatments.

11 Jun 2020

Hydroxychloroquine suppresses 'trained immunity'

A new study published on the preprint server medRxiv in June 2020 shows that the drug hydroxychloroquine (HCQ) suppresses a form of immunity called ‘trained immunity,’ with repercussions for its potential use to treat COVID-19.

11 Jun 2020

Immuno-oncology may accelerate the development of treatments for COVID-19

Researchers at Roswell Park Comprehensive Cancer Center have been actively engaged in the effort to develop treatments or other control strategies that can help communities worldwide to address the impacts of the COVID-19 pandemic.

10 Jun 2020

Fecal transplants could be used as treatment for non-alcoholic fatty liver disease

A new study from Lawson Health Research Institute and Western University suggests that fecal transplants could be used as a treatment for non-alcoholic fatty liver disease.

9 Jun 2020

Georgia State researcher receives $1.95 million NIH grant to study cause of autoimmunity

Dr. Leszek Ignatowicz, a professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $1.95 million federal grant to study what causes autoimmunity in the human body.

8 Jun 2020

Health care providers urged to stop hydroxycholoroquine use for COVID-19

The sacred oath taken by physicians during graduation from medical school to "First do no harm," the first words of the Hippocratic Oath, provides a strong impetus for a commentary just published in The American Journal of Medicine.

4 Jun 2020

Lancet issues correction on paper than prompted WHO to suspend Hydroxychloroquine trial

The World Health Organization (WHO) suspended the hydroxychloroquine trial amid the coronavirus pandemic. The decision comes after the study findings published in The Lancet reported issues on the drug's efficacy and safety. Now, the journal has issued a correction on the figures reported in the study.

2 Jun 2020

Researchers develop new method to measure hydroxychloroquine levels in SLE patients

Researchers at Uppsala University and Uppsala University Hospital have developed a new method to measure levels of the medication hydroxychloroquine in patients with rheumatic disease systemic lupus erythematosus (SLE).

1 Jun 2020