Lupus News and Research

Latest Lupus News and Research

The 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease released

The American College of Rheumatology and the European League Against Rheumatism released the 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease. It is the first criteria developed specifically for this recently recognized disease.

4 Dec 2019

Sphingolipids associated with heart disease in African Americans with lupus

When it comes to cholesterol, we've come to accept a simple narrative. Our risk of heart disease is lower when we have more "good cholesterol," or high-density lipoproteins (HDL), and less "bad cholesterol," or low-density lipoproteins (LDL) and triglycerides.

21 Nov 2019

Malaria research advances immunotherapy in lupus, HIV

A new study published on November 19, 2019, in the journal Cell Reports, shows how the body’s immune system responds to malaria, which in turn promises to teach scientists how to design more effective therapies for a range of illnesses that are modulated by the immune response.

19 Nov 2019

Male patients with lupus often have more severe disease, receive little support

A national survey of male patients with lupus finds the illness has a significant impact on their physical and emotional health, yet they often do not receive support that could help them cope.

11 Nov 2019

Acute kidney injury on the rise in hospitalized pregnant women

A study presented at ASN Kidney Week 2019 (November 5 to November 10) shows that the rate of acute kidney injury (AKI) is rising among US women who are hospitalized in pregnancy. The highest risk is in pregnant diabetic women. Women who suffer acute damage to the kidney while pregnant have 260 times the risk of death while in hospital compared to other pregnant women, at 2.6% vs 0.01%. Both mother and baby are at risk of increased illness and death if the woman has kidney injury during pregnancy.

11 Nov 2019

New textbook on mysterious and deadly cytokine storm syndrome

There's no telling where the call will come from, or when. But Randy Cron, M.D., Ph.D., professor of pediatrics and medicine at UAB, knows to expect them.

11 Nov 2019

Lupus flare-ups could be linked to environmental factors

Researchers have found that alteration in the environment and atomospheric factors could be associated with organ specific flare-ups of lupus among patients diagnosed with Systemic Lupus Erethematosus (SLE). The study results were presented at the 2019 ACR/ARP Annual Meeting. The abstract was titled, “Environmental and Atmospheric Factors in Systemic Lupus Erythematosus: A Regression Analysis.”

11 Nov 2019

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, adenosine deaminase 2 (ADA2) in the peripheral blood is a sensitive, specific biomarker for macrophage activation syndrome, a potentially life-threatening complication of systemic juvenile idiopathic arthritis (systemic JIA)

10 Nov 2019

Additional medications needed to control the symptoms of juvenile idiopathic arthritis

According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, there is a profound ongoing need for additional medications to control the signs and symptoms of juvenile idiopathic arthritis, despite the availability of several approved biologic disease-modifying antirheumatic drugs (biologics).

10 Nov 2019

Atmospheric and environmental changes linked to organ-specific lupus flares

New research findings presented at the 2019 ACR/ARP Annual Meeting found a strong association between changes in atmospheric and environmental variables 10 days before a clinic visit and organ-specific lupus flares in patients with systemic lupus erythematosus.

10 Nov 2019

New technique to detect common cause for diseases related to thrombotic microangiopathies

There is a group of diseases whose symptoms have a common origin: a lesion in the endothelial tissue that covers the inside of the blood vessels.

8 Nov 2019

Vitamin D and omega-3 fatty acids are not effective at reducing systemic inflammation

Vitamin D and marine omega-3 fatty acids -- also known as fish oil -- are purported to have many health benefits, including reducing systemic inflammation.

7 Nov 2019

Study finds molecular key to formation of mature and fully functioning T cells

In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.

25 Oct 2019

Scientists pinpoint epigenetic differences in the way lupus affects black women

Scientists at the HudsonAlpha Institute for Biotechnology have pinpointed epigenetic differences in the way lupus affects black women compared to other lupus patients, revealing important mechanics of the puzzling disease.

24 Oct 2019

Study opens up array of options for developing treatments for cancer or autoimmune disorder

Immunologists at St. Jude Children's Research Hospital have discovered key biological switches that control regulatory T cells--specialized white blood cells that keep the immune system in check.

24 Oct 2019

Celiac disease may now be curable with biodegradable nanoparticles

A phase 2 trial just concluded shows that people with celiac disease may now be able to hope for a cure, through a treatment that makes the immune system tolerant towards gluten. This could eventually make it possible for such individuals to eat gluten-containing foods without fear.

22 Oct 2019

Neutrophil extracellular traps could cause organ damage in malaria

Malaria is one of the world's deadliest infectious diseases: a small mosquito bite delivers numerous malaria parasites into the bloodstream. The human body defends itself valiantly against the parasite, which usually results in periodic flu-like symptoms and severe fever. Severe cases of the disease are accompanied by tissue damage and result in potentially fatal organ failure.

21 Oct 2019

Study receives NCI grant to explore better treatment for brain tumors in children

Children with recurrent brain tumors or newly diagnosed, particularly aggressive tumors called diffuse intrinsic pontine gliomas are being enrolled in the first study to examine the efficacy of a drug that inhibits an enzyme these tumors use to protect themselves from the child's natural immune response.

8 Oct 2019

Scientists show how protein Ikaros orchestrates fine balance to control autoimmunity

The immune system relies on B cells and their ability to make antibodies against an extremely broad range of pathogens. This broad responsiveness bears some risk, as B cells can also turn against healthy tissue - a phenomenon called autoimmunity.

8 Oct 2019

Study finds nearly one in three patients with lupus uses prescription opioids for pain

Although there is little evidence that opioids effectively reduce pain from rheumatic diseases, a new study finds nearly one in three patients with lupus uses prescription opioids, often lasting longer than a year.

26 Sep 2019

Lupus News and Research

Latest Lupus News and Research

The 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease released

Sphingolipids associated with heart disease in African Americans with lupus

Malaria research advances immunotherapy in lupus, HIV

Male patients with lupus often have more severe disease, receive little support

Acute kidney injury on the rise in hospitalized pregnant women

New textbook on mysterious and deadly cytokine storm syndrome

Lupus flare-ups could be linked to environmental factors

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

Additional medications needed to control the symptoms of juvenile idiopathic arthritis

Atmospheric and environmental changes linked to organ-specific lupus flares

New technique to detect common cause for diseases related to thrombotic microangiopathies

Vitamin D and omega-3 fatty acids are not effective at reducing systemic inflammation

Study finds molecular key to formation of mature and fully functioning T cells

Scientists pinpoint epigenetic differences in the way lupus affects black women

Study opens up array of options for developing treatments for cancer or autoimmune disorder

Celiac disease may now be curable with biodegradable nanoparticles

Neutrophil extracellular traps could cause organ damage in malaria

Study receives NCI grant to explore better treatment for brain tumors in children

Scientists show how protein Ikaros orchestrates fine balance to control autoimmunity

Study finds nearly one in three patients with lupus uses prescription opioids for pain

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Lupus News and Research

Latest Lupus News and Research

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

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