Metabolism News and Research

Latest Metabolism News and Research

Tirzepatide helps people without diabetes lose 13% body weight in real-world study

A real-world study of over 4,000 US patients without type 2 diabetes found that those who persisted with Tirzepatide for at least six months lost an average of 12.9% of their body weight. The study highlights Tirzepatide’s potential as an effective off-label obesity treatment before its formal FDA approval for weight loss.

11 Mar 2025

Is fluoride safe for your gut? New study investigates

Systematic review finds that while low-dose fluoride has little effect on gut microbiota, high doses disrupt microbial diversity and balance, especially in animal studies. The effects vary by species, fluoride form, and exposure level, raising concerns about high-dose fluoride impacts on gut health.

11 Mar 2025

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a growing global health concern, affecting millions worldwide. This complex liver disorder ranges from simple steatosis to more severe forms, including metabolic dysfunction-associated steatohepatitis (MASH), which may progress to fibrosis, cirrhosis, and even liver cancer.

11 Mar 2025

Decoding programmed cell death in breast cancer

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC remains a significant global health challenge.

11 Mar 2025

Study reveals TCM-Based strategies for ferroptosis modulation

Innovative insights into the role of ferroptosis, a unique form of programmed cell death, are reshaping the landscape of disease treatment. This growing field highlights how Traditional Chinese Medicine (TCM) can effectively modulate ferroptosis, offering novel therapeutic approaches for various conditions, including cancer, cardiovascular diseases, neurodegenerative disorders, and organ injuries.

11 Mar 2025

Platelet-rich plasma may enhance ovarian rejuvenation and improve egg quality in women

A new research paper was published in Aging (Aging-US) on February 18, 2025, Volume 17, Issue 2, titled "Transcriptomic landscape of cumulus cells from patients <38 years old with a history of poor ovarian response (POR) treated with platelet-rich plasma (PRP)."

10 Mar 2025

Cordycepin helps tired mice run longer and think better, study finds

Researchers show that cordycepin, a compound from Cordyceps militaris, can boost endurance and protect brain function in mice exhausted by excessive exercise.

10 Mar 2025

Is red meat good or bad for you? Study explains how amino acids shape the answer

Researchers at Texas Tech University reviewed how red meat proteins and amino acids affect human health, weighing both benefits and risks. Their findings highlight that while red meat provides vital nutrients, overconsumption and poor preparation methods can increase disease risk.

10 Mar 2025

New stem cell-based vascular grafts could revolutionize cardiac surgery

Scientists at the Wisconsin National Primate Research Center (WNPRC) and the Morgridge Institute for Research at the University of Wisconsin–Madison have been at the forefront of stem cell research and regenerative biology since James Thomson isolated the first human embryonic stem cell in 1998.

10 Mar 2025

Walking more steps and exercise linked to lower risk of death in postmenopausal cancer survivors

Among postmenopausal women with a history of cancer, taking more daily steps and engaging in moderate-to-vigorous physical activity were both associated with a significantly reduced risk of death from cardiovascular disease, according to preliminary research presented at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2025.

10 Mar 2025

Restoring gut health in ulcerative colitis through microbiome-based therapy

The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health.

10 Mar 2025

Reprogramming T cells to overcome tumor challenges

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and their collaborators demonstrated a remarkable ability to boost the immune system's fight against cancer, showing promise for improving patient outcomes in difficult-to-treat malignancies.

10 Mar 2025

Why do some people need supplements and others don’t? New review explains

New research in The New England Journal of Medicine reviews current knowledge on micronutrient requirements, deficiencies, and interventions. It highlights the need for targeted supplementation and calls for advanced research to better diagnose and treat hidden deficiencies.

9 Mar 2025

Can microbiome discoveries finally become treatments? Scientists show the way

Researchers propose a novel iterative strategy combining big data and experimental models to move microbiome research from theory to clinical applications. The study highlights the need to bridge the gap between correlation and causation to develop effective microbiome-based therapies.

9 Mar 2025

These simple diet tweaks could slash microplastics in your body

Researchers identify dietary and lifestyle-based strategies that may reduce human exposure to microplastics and nanoplastics.

9 Mar 2025

Research links kidney dysfunction to muscle weakness in myotonic dystrophy type 1

Thurman M. Wheeler, MD, of the Department of Neurology at Massachusetts General Hospital, is the senior author of a paper published in Nature Communications, "Analysis of human urinary extracellular vesicles reveals disordered renal metabolism in myotonic dystrophy type 1."

8 Mar 2025

Evaluating the combined effect of electroacupuncture and Chinese herbal medicine on gut microbiota in ALS patients

Recent studies have highlighted a link between amyotrophic lateral sclerosis (ALS) and gut microbiota. This prospective study aimed to evaluate the effects of electroacupuncture combined with Chinese herbal medicine on gut microbiota and metabolomics in ALS patients.

7 Mar 2025

Study finds link between pregnancy mineral levels and lower blood pressure in midlife

Women with higher levels of essential minerals circulating in their blood during pregnancy, particularly copper and manganese, along with vitamin B12, had a lower risk of developing high blood pressure in middle age, about 20 years later, according to research presented at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2025.

6 Mar 2025

Pacific Islander, Native Hawaiian and Asian American populations show varying heart disease risk factors

Asian American, Native Hawaiian and other Pacific Islander (AANHPI) populations experienced differences in both cardiovascular disease predicted risk and risk factors, according to preliminary research presented at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2025.

6 Mar 2025

Asah1 gene plays key role in preventing progression of nonalcoholic fatty liver disease

Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic fatty liver diseases (NAFLD) into more severe forms of liver disease by regulating hepatic lipid homeostasis and cellular maintenance processes.

6 Mar 2025

Metabolism News and Research

Latest Metabolism News and Research

Tirzepatide helps people without diabetes lose 13% body weight in real-world study

Is fluoride safe for your gut? New study investigates

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Decoding programmed cell death in breast cancer

Study reveals TCM-Based strategies for ferroptosis modulation

Platelet-rich plasma may enhance ovarian rejuvenation and improve egg quality in women

Cordycepin helps tired mice run longer and think better, study finds

Is red meat good or bad for you? Study explains how amino acids shape the answer

New stem cell-based vascular grafts could revolutionize cardiac surgery

Walking more steps and exercise linked to lower risk of death in postmenopausal cancer survivors

Restoring gut health in ulcerative colitis through microbiome-based therapy

Reprogramming T cells to overcome tumor challenges

Why do some people need supplements and others don’t? New review explains

Can microbiome discoveries finally become treatments? Scientists show the way

These simple diet tweaks could slash microplastics in your body

Research links kidney dysfunction to muscle weakness in myotonic dystrophy type 1

Evaluating the combined effect of electroacupuncture and Chinese herbal medicine on gut microbiota in ALS patients

Study finds link between pregnancy mineral levels and lower blood pressure in midlife

Pacific Islander, Native Hawaiian and Asian American populations show varying heart disease risk factors

Asah1 gene plays key role in preventing progression of nonalcoholic fatty liver disease

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows