Metabolism News and Research

Latest Metabolism News and Research

Disruption of circadian clock linked to accelerated colorectal cancer progression

Research from the University of California, Irvine has revealed how disruption of the circadian clock, the body's internal, 24-hour biological pacemaker, may accelerate the progression of colorectal cancer by affecting the gut microbiome and intestinal barrier function.

27 Sep 2024

Novel approach combines glutaminase and HuR blockade to suppress breast cancer growth

A study led by Brazilian researchers and reported in an article published in the journal Nature Communications proposes that simultaneously targeting the enzyme glutaminase and the protein HuR, both of which are essential to tumor progression, may be effective in treating breast cancer.

27 Sep 2024

Why hypoglycemia-induced glucagon secretion becomes impaired in diabetes

Findings indicate that excessive somatostatin inhibits glucagon secretion in type 1 diabetes, offering a novel target for hypoglycemia management strategies.

27 Sep 2024

12-week coffee compound study shows promising results for weight and fat reduction in at-risk individuals

Cafestol may aid in reducing body weight and visceral fat, but its impact on insulin sensitivity and glucose tolerance remains limited, according to the study.

27 Sep 2024

Liver receptor mutations linked to liver dysfunction, cholesterol accumulation, and hepatitis

Damaging LXRα variants are linked to liver cholesterol buildup and hepatitis, emphasizing the receptor's importance in cholesterol sensing and liver function.

27 Sep 2024

New insights into serine hydroxymethyltransferase aid cancer drug design

In just two neutron experiments, scientists discovered remarkable details about the function of an enzyme that can aid drug design for aggressive cancers.

26 Sep 2024

Study reveals positive correlation between type 2 immunity and long-term cancer remission

Results from a preclinical study in mice, led by EPFL, and a collaborative clinical study in patients show that the type 2 immune response – associated with parasitic infection and thought to play a negative role in cancer immunity – is positively correlated with long-term cancer remission.

26 Sep 2024

Purine metabolism disruptions highlighted as crucial in Parkinson’s disease development

Parkinson's disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its progressive nature and debilitating effects on motor function.

26 Sep 2024

Ultra-processed foods are silently altering your metabolism, scientists warn

Researchers from Germany and France uncover how ultra-processed foods impact metabolism in adolescents and young adults by analyzing urine and plasma biomarkers. Their findings suggest potential health risks linked to frequent consumption of processed foods.

26 Sep 2024

Insufficient sleep during pregnancy associated with neurodevelopmental risks in offspring

Pregnant women who do not get enough sleep may be at higher risk of having children with neurodevelopmental delays, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

26 Sep 2024

Maternal obesity doubles the risk of developing autism in children

Researchers investigate the potential relationship between maternal fat mass and long-term mental health issues in children born to these mothers.

26 Sep 2024

Genetic factors that make the bacteria behind cholera so dangerous uncovered

Study reveals key genetic factors in Vibrio cholerae O1 that drive cholera transmission and severity, highlighting targets for novel therapeutic strategies.

26 Sep 2024

Researchers explore new metabolic pathway to fight cancer

When an aggressive cancer launches an invasion on the human body, anything that can be done to slow down or better understand that fast-paced assault is going to be a bonus.

26 Sep 2024

Study: Obstructive sleep apnea may be a risk factor for abdominal aortic aneurysms

Obstructive sleep apnea may be a risk factor for developing abdominal aortic aneurysms, according to researchers from the University of Missouri School of Medicine and NextGen Precision Health.

25 Sep 2024

Researchers identify drug with anti-aging effects

Aging is an inevitable phenomenon and is accompanied by several comorbidities. To this end, research into the effects of aging has become paramount, and scientists are looking for ways to slow down aging and its detrimental impact on the human body.

25 Sep 2024

Researchers gain new understanding of how immune cells respond to heat during fever

The study reveals that moderate fever enhances CD4 T cell activity while reducing regulatory T cell suppression, highlighting temperature's immune effects.

25 Sep 2024

Study links youth prediabetes to increased pregnancy risks later in life

New research conducted at Columbia Mailman School of Public Health and Mount Sinai School of Medicine shows a link between prediabetes among young people and adverse pregnancy outcomes later in life.

24 Sep 2024

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Research connects gut microbiota to lupus and IBD, uncovering microbial markers and pathways that could inform targeted therapies for autoimmune disorders.

24 Sep 2024

A week of intense cycling may burn abdominal fat without major weight loss, study finds

A week of extreme cycling significantly decreased visceral adiposity in middle-aged cyclists, emphasizing the role of exercise in body composition management.

23 Sep 2024

Blood microRNAs can predict conversion from mild cognitive impairment to dementia due to Alzheimer’s disease

This study identifies serum miRNA signatures as promising biomarkers for Alzheimer's, enhancing prediction of MCI conversion to AD with clinical relevance.

23 Sep 2024

Metabolism News and Research

Latest Metabolism News and Research

Disruption of circadian clock linked to accelerated colorectal cancer progression

Novel approach combines glutaminase and HuR blockade to suppress breast cancer growth

Why hypoglycemia-induced glucagon secretion becomes impaired in diabetes

12-week coffee compound study shows promising results for weight and fat reduction in at-risk individuals

Liver receptor mutations linked to liver dysfunction, cholesterol accumulation, and hepatitis

New insights into serine hydroxymethyltransferase aid cancer drug design

Study reveals positive correlation between type 2 immunity and long-term cancer remission

Purine metabolism disruptions highlighted as crucial in Parkinson’s disease development

Ultra-processed foods are silently altering your metabolism, scientists warn

Insufficient sleep during pregnancy associated with neurodevelopmental risks in offspring

Maternal obesity doubles the risk of developing autism in children

Genetic factors that make the bacteria behind cholera so dangerous uncovered

Researchers explore new metabolic pathway to fight cancer

Study: Obstructive sleep apnea may be a risk factor for abdominal aortic aneurysms

Researchers identify drug with anti-aging effects

Researchers gain new understanding of how immune cells respond to heat during fever

Study links youth prediabetes to increased pregnancy risks later in life

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

A week of intense cycling may burn abdominal fat without major weight loss, study finds

Blood microRNAs can predict conversion from mild cognitive impairment to dementia due to Alzheimer’s disease

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