Metabolism News and Research

Latest Metabolism News and Research

Liraglutide activates key brain circuits to trigger weight loss in obesity

Researchers uncover how liraglutide targets specific brain regions to suppress appetite and promote significant weight loss through GLP-1 receptor activation.

23 Sep 2024

Yoyo dieting alters gut health, driving weight regain and inflammation

Researchers from Deakin University reveal how yoyo dieting disrupts gut health, leading to weight regain and obesity-related complications. The study highlights the roles of gut microbiota, hormones, and inflammation in the weight cycling process.

23 Sep 2024

Fever enhances immune cell activity and induces mitochondrial stress

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also - in a particular subset of T cells - cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers have discovered.

20 Sep 2024

Virginia Tech researchers uncover bacterial infection mechanism

Virginia Tech researchers have learned how bacteria manipulate molecules to infect the host organism.

20 Sep 2024

Lipid biomarkers in children with obesity linked to future cardiometabolic risks

Scientists from the University of Copenhagen have detected lipid biomarkers in children and teenagers with obesity that indicate an increased risk of developing type 2 diabetes, liver and heart disease as adults.

20 Sep 2024

How plant-based, Mediterranean, and Western diets affect gut microbiota and disease

Researchers examine how different dietary components affect the gut microbiome and development of non-communicable diseases.

20 Sep 2024

Childhood adversity linked to elevated health risks, differing by sex and stress

Researchers assess the heterogeneous effects of childhood adversity on disease biomarkers and health conditions in adulthood.

20 Sep 2024

New blood test identifies obesity-related health risks in children

A new type of blood test using lipids could make it easier to identify children at risk of complications around obesity including type two diabetes, liver and heart disease, say scientists.

20 Sep 2024

Lipid metabolism plays a critical role in red blood cell recovery from acute anemia

Red blood cells are the most abundant cells in the body. It has long been known that when red blood cells break down or anemia occurs due to bleeding, the hormone erythropoietin (EPO) increases, leading to the proliferation of immature cells (erythroblasts) that eventually become red blood cells, thus restoring the red blood cell count.

20 Sep 2024

New tool spots drug-resistant bacteria before treatment

Penicillin was hailed as "the silver bullet" when it was discovered, as it had the unprecedented quality of being able to kill disease-causing bacteria without harming the human body. Since then, a multitude of other antibiotics have been developed that specifically target a wide range of bacteria; but the more often they are used, the greater the risk that antibiotic-resistant strains will arise.

19 Sep 2024

Researchers identify bacterial strains to combat antibiotic-resistant gut infections

Antibiotic-resistant bacterial infections often occur in patients with chronic inflammatory intestinal conditions, such as inflammatory bowel disease, and in patients who have taken antibiotics for a long time.

19 Sep 2024

Cellular sludge around hunger neurons linked to worsening diabetes and obesity

Investigating ECM changes in the hypothalamus reveals mechanisms behind insulin resistance, offering insights into obesity and metabolic disease treatment.

19 Sep 2024

Study explores microglial response to chronic hyponatremia and rapid sodium correction

Low serum sodium concentrations in blood are called hyponatremia, a prevalent clinical electrolyte disorder.

18 Sep 2024

Impact of oxidative stress, gut, and diet on attention deficit hyperactivity disorder pathophysiology

Oxidative stress and gut microbiome interactions are key in ADHD pathogenesis, with diet playing a crucial role in managing symptoms and improving outcomes.

18 Sep 2024

The importance of mitochondrial function in health and disease

The World Mitochondria Society (WMS) is preparing for its annual Targeting Mitochondria 2024 conference, which will focus on innovative strategies to "charge" cells by supplying them with extra mitochondria to enhance cellular function and combat diseases.

18 Sep 2024

Lipid molecule fuels cancer growth

Cancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags right on their membranes. Once alerted, the body's defenses can swoop in, destroying rogue cells before they can do much damage. Lying at the heart of this early warning system are lipids, fatty compounds previously seen by cancer biologists primarily as a fuel source for burgeoning tumors.

18 Sep 2024

New insights into the mechanisms of efavirenz-induced neurotoxicity

Efavirenz is an important drug for treating HIV infection, but it has negative effects that can significantly impact patients' quality of life over time. It causes neuropsychiatric disorders and neurocognitive impairment in roughly 50 percent of patients. The drug is associated with abnormal lipid levels in blood plasma, but the molecular mechanisms responsible for negative clinical observations are unknown.

18 Sep 2024

Mechanically stimulated 3D multicellular systems

To study biomechanical forces in multicellular systems, effective mechanical stimulation is an essential tool. A 3D microstructure device is developed using Two-Photon Polymerization (2PP)-based 3D printing for mimicking the human multicellular environment.

From Nanoscribe GmbH & Co. KG 18 Sep 2024

UCLA study links childhood trauma to sex-specific health risks later in life

A new study led by UCLA Health found that a person's sex and their unique experiences of childhood trauma can have specific consequences for their biological health and risk of developing 20 major diseases later in life.

17 Sep 2024

Assessing the impact of weight loss and blood sugar control in people with type 2 diabetes

A Cleveland Clinic research team has published the first study assessing the independent real-world impacts of weight loss and blood sugar control on clinical outcomes in people with type 2 diabetes treated with antidiabetic medications, and specifically with GLP-1RAs (the class of drug that includes Ozempic and Wegovy).

17 Sep 2024

Metabolism News and Research

Latest Metabolism News and Research

Liraglutide activates key brain circuits to trigger weight loss in obesity

Yoyo dieting alters gut health, driving weight regain and inflammation

Fever enhances immune cell activity and induces mitochondrial stress

Virginia Tech researchers uncover bacterial infection mechanism

Lipid biomarkers in children with obesity linked to future cardiometabolic risks

How plant-based, Mediterranean, and Western diets affect gut microbiota and disease

Childhood adversity linked to elevated health risks, differing by sex and stress

New blood test identifies obesity-related health risks in children

Lipid metabolism plays a critical role in red blood cell recovery from acute anemia

New tool spots drug-resistant bacteria before treatment

Researchers identify bacterial strains to combat antibiotic-resistant gut infections

Cellular sludge around hunger neurons linked to worsening diabetes and obesity

Study explores microglial response to chronic hyponatremia and rapid sodium correction

Impact of oxidative stress, gut, and diet on attention deficit hyperactivity disorder pathophysiology

The importance of mitochondrial function in health and disease

Lipid molecule fuels cancer growth

New insights into the mechanisms of efavirenz-induced neurotoxicity

Mechanically stimulated 3D multicellular systems

UCLA study links childhood trauma to sex-specific health risks later in life

Assessing the impact of weight loss and blood sugar control in people with type 2 diabetes

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy