Neurology News and Research

Latest Neurology News and Research

Amyloid clue to Parkinson’s dementia

Study findings link amyloid β burden to future cognitive decline in patients with Parkinson’s disease.

22 Jan 2013

STN confirmed as preferred stimulation target in Parkinson’s

Subthalamic nucleus stimulation is at worst equivalent and at best superior to globus pallidus pars interna stimulation in patients with Parkinson’s disease, shows a randomized trial.

22 Jan 2013

Management of hospital-onset seizures lacks standards

Seizures in patients admitted to hospital for nonseizure reasons – hospital-onset seizures – largely affect those without any history of seizures, often recur, and are linked to a high mortality, according to a study in JAMA Neurology.

21 Jan 2013

Low blood flow to the premature brain disrupts cells' ability to fully mature

Physician-scientists at Oregon Health & Science University Doernbecher Children's Hospital are challenging the way pediatric neurologists think about brain injury in the pre-term infant. In a study published online in the Jan. 16 issue of Science Translational Medicine, the OHSU Doernbecher researchers report for the first time that low blood and oxygen flow to the developing brain does not, as previously thought, cause an irreversible loss of brain cells, but rather disrupts the cells' ability to fully mature.

19 Jan 2013

Preterm infants with slower growth have delayed development in the cerebral cortex

Preterm infants who grow more slowly as they approached what would have been their due dates also have slower development in an area of the brain called the cerebral cortex, report Canadian researchers in a new study published today in Science Translational Medicine.

17 Jan 2013

Athletes with concussions in early adulthood may be at increased risk of depression as they age

National Football League (NFL) players may be at increased risk of depression as they age due to brain damage resulting from concussions, according to two studies released today that will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013.

17 Jan 2013

Women who have migraine with aura more likely to develop major cardiovascular events

Women who have migraines with aura, which are often visual disturbances such as flashing lights, may be more likely to have problems with their heart and blood vessels, and those on newer contraceptives may be at higher risk for blood clots, according to two studies released today that will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013.

17 Jan 2013

Boehringer Ingelheim receives FDA Priority Review for afatinib to treat EGFR mutation-positive NSCLC

Boehringer Ingelheim today announced that the New Drug Application (NDA) for its investigational oncology compound afatinib has been accepted for filing and granted Priority Review by the U.S. Food and Drug Administration (FDA).

17 Jan 2013

ARHGEF28 gene mutations present in amyotrophic lateral sclerosis: Research

Researchers at Western University in London, Canada, have identified a new genetic mutation for amyotrophic lateral sclerosis (ALS), opening the door to future targeted therapies. Dr. Michael Strong, a scientist with Western's Robarts Research Institute and Distinguished University Professor in Clinical Neurological Sciences at the Schulich School of Medicine & Dentistry, and colleagues found that mutations within the ARHGEF28 gene are present in ALS.

16 Jan 2013

Researchers identify new group of growth factor receptors that signal to brain tumours

One in 25,000 people worldwide is affected by neurofibromatosis type 2 (NF2), a condition where the loss of a tumour suppressor called Merlin results in multiple tumours in the brain and nervous system.

16 Jan 2013

Stroke survivors with depression more likely to die

People who are depressed after a stroke may have a tripled risk of dying early and four times the risk of death from stroke than people who have not experienced a stroke or depression, according to a study that will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013.

16 Jan 2013

Speech entrainment benefits stroke victims with Broca's aphasia

Stroke victims affected with loss of speech caused by Broca's aphasia have been shown to speak fluidly through the use of a process called "speech entrainment" developed by researchers at the University of South Carolina's Arnold School of Public Health.

16 Jan 2013

Elan, Biogen Idec submit applications to FDA and EMA for updation of TYSABRI labels

Today Biogen Idec and Elan Corporation, plc announced that they have submitted applications to the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA) requesting updates to the TYSABRI (natalizumab) labels.

16 Jan 2013

Jan. issue of Behavioural Neurology features papers on aphasia and hemispatial neglect

Approximately half a million individuals suffer strokes in the US each year, and about one in five develops some form of post-stroke aphasia, the partial or total loss of the ability to communicate. By comparing different types of aphasia, investigators have been able to gain new insights into the normal cognitive processes underlying language, as well as the potential response to interventions.

16 Jan 2013

People with early Parkinson's frequently experience many non-motor symptoms

While movement problems are the main symptom of Parkinson's disease, a new study shows that even early in the course of disease people frequently experience many non-motor symptoms such as drooling, anxiety and constipation.

16 Jan 2013

Study finds primary factors that increase risk of mortality in subarachnoid haemorrhage survivors

"It is particularly important for subarachnoid haemorrhage survivors to refrain from smoking and to take care of their blood pressure and cholesterol levels; apart from age, these are the primary factors behind the increased risk of mortality," explains neurosurgeon Miikka Korja from the HUCH's Neurosurgery Department together with professor Jaakko Kaprio from the University of Helsinki's Hjelt Institute.

16 Jan 2013

Vanderbilt University, AstraZeneca partner to identify candidate drugs for major brain diseases

Today, AstraZeneca and Vanderbilt University announced they have signed a research collaboration agreement to identify candidate drugs aimed at treating psychosis and other neuropsychiatric symptoms associated with major brain diseases such as Alzheimer's disease and schizophrenia.

16 Jan 2013

Children with chronic medical conditions more likely to use alternative medicine

Children who regularly see specialists for chronic medical conditions are also using complementary medicine at a high rate, demonstrates recently published research from the University of Alberta and the University of Ottawa.

15 Jan 2013

Off-label drug ineffective in frontotemporal dementia

A randomized, controlled trial has dashed hopes that memantine therapy could benefit patients with frontotemporal dementia.

14 Jan 2013

Results from Morphotek’s farletuzumab Phase III combination study on ovarian cancer

Morphotek Inc., a wholly-owned subsidiary of Eisai Inc., announced today top-line results from a Phase III study of its investigational agent farletuzumab (MORAb-003) in combination with carboplatin and a taxane in patients with platinum-sensitive epithelial ovarian cancer in first relapse.

11 Jan 2013

Neurology News and Research

Latest Neurology News and Research

Amyloid clue to Parkinson’s dementia

STN confirmed as preferred stimulation target in Parkinson’s

Management of hospital-onset seizures lacks standards

Low blood flow to the premature brain disrupts cells' ability to fully mature

Preterm infants with slower growth have delayed development in the cerebral cortex

Athletes with concussions in early adulthood may be at increased risk of depression as they age

Women who have migraine with aura more likely to develop major cardiovascular events

Boehringer Ingelheim receives FDA Priority Review for afatinib to treat EGFR mutation-positive NSCLC

ARHGEF28 gene mutations present in amyotrophic lateral sclerosis: Research

Researchers identify new group of growth factor receptors that signal to brain tumours

Stroke survivors with depression more likely to die

Speech entrainment benefits stroke victims with Broca's aphasia

Elan, Biogen Idec submit applications to FDA and EMA for updation of TYSABRI labels

Jan. issue of Behavioural Neurology features papers on aphasia and hemispatial neglect

People with early Parkinson's frequently experience many non-motor symptoms

Study finds primary factors that increase risk of mortality in subarachnoid haemorrhage survivors

Vanderbilt University, AstraZeneca partner to identify candidate drugs for major brain diseases

Children with chronic medical conditions more likely to use alternative medicine

Off-label drug ineffective in frontotemporal dementia

Results from Morphotek’s farletuzumab Phase III combination study on ovarian cancer

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

Neurology News and Research

Latest Neurology News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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